Results 241 to 250 of about 840,795 (338)

Longitudinal MRI‐Driven Multi‐Modality Approach for Predicting Pathological Complete Response and B Cell Infiltration in Breast Cancer

Advanced Science, Volume 12, Issue 12, March 27, 2025.
This study develops a multi‐modality model integrating longitudinal magnetic resonance imaging, transcriptomic, and scRNA‐seq data to predict pathological complete response (pCR) in breast cancer. It outperforms traditional radiomics models, offering non‐invasive pCR prediction and help guide treatment decisions.
Yu‐Hong Huang, Zhen‐Yi Shi, Teng Zhu, Tian‐Han Zhou, Yi Li, Wei Li, Han Qiu, Si‐Qi Wang, Li‐Fang He, Zhi‐Yong Wu, Ying Lin, Qian Wang, Wen‐Chao Gu, Chang‐Cong Gu, Xin‐Yang Song, Yang Zhou, Dao‐Gang Guan, Kun Wang   +17 more
wiley   +1 more source

Revealing the Transcriptional and Metabolic Characteristics of Sebocytes Based on the Donkey Cell Transcriptome Atlas

Advanced Science, Volume 12, Issue 16, April 24, 2025.
In this study, a comprehensive single‐cell transcriptome atlas of the Dezhou donkey, encompassing 20 tissues and 275 050 cells, is constructed. Through cross‐species and cross‐tissue analyses, distinct transcriptional patterns in donkey sebocytes are identified.
Yu Tian, Shuqin Liu, Hongtao Shi, Jianjun Li, Xinglong Wan, Yujiang Sun, Huayun Li, Ning Cao, Zhixi Feng, Teng Zhang, Junjie Wang, Wei Shen   +11 more
wiley   +1 more source

Pseudodicentric chromosome 18 diagnosed by chromosome painting and primed in situ labelling (PRINS). [PDF]

, 1994
C A Brandt, Birgitte Wilton Djernes, Helle Strømkjær, Michael B. Petersen, S. Pedersen, Johnny Hindkjær, J Brinch-Iversen, G. Bruun‐Petersen   +7 more
openalex   +1 more source

Origin of B chromosomes in the genus Astyanax (Characiformes, Characidae) and the limits of chromosome painting

Zeitschrift für Induktive Abstammungs- und Vererbungslehre, 2016
Duílio M. Z. A. Silva, S. N. Daniel, J. Camacho, R. Utsunomia, Francisco J. Ruiz-Ruano, Manolo Penitente, J. C. Pansonato-Alves, D. Hashimoto, C. Oliveira, F. Porto‐Foresti, F. Foresti   +10 more
semanticscholar   +1 more source

KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β‐Catenin Signaling Pathway

Advanced Science, EarlyView.
In KLF1‐on (neonatal and Klf1 overexpression hearts) models, KLF1 regulates Wnt/β‐catenin signaling pathway and the expression of cell proliferation‐related genes via transcriptional and epigenetic mechanisms, which induces cardiomyocyte proliferation and cardiac regeneration in mice after myocardial infarction.
Yanglin Hao, Xi Zhang, Shuan Ran, Yuan Li, Weicong Ye, Song Wang, Xiaohan Li, Zilong Luo, Jiulu Zhao, Junjie Zong, Kexiao Zheng, Ran Li, Han Zhang, Longyong Lai, Pinyan Huang, Zifeng Zou, Wang Zhan, Zhang Yue, Jie Wu, Jiahong Xia   +19 more
wiley   +1 more source

Painting of Human Chromosome 8 in Fifteen Minutes [PDF]

, 1996
Markus Durm, Michael Hausmann, Klaus Aldinger, H. Ludwig, Christoph Cremer   +4 more
openalex   +1 more source

Direct Quantification of Protein–Protein Interactions in Living Bacterial Cells

Advanced Science, EarlyView.
Quantitative measurement of protein–protein interactions in living cells is vital for biotechnology applications. Fluorescence resonance energy transfer (FRET) signals in bacterial cells are often weak, leading to false‐positive. Quantitative FRET measurements are implemented to overcome the weak FRET signal.
Soojung Yi, Eunji Kim, Sora Yang, Gyeongmin Kim, Da‐Woon Bae, Se‐Young Son, Bo‐Gyeong Jeong, Jeong Seok Ji, Hyung Ho Lee, Ji‐Sook Hahn, Sun‐Shin Cha, Yeo Joon Yoon, Nam Ki Lee   +12 more
wiley   +1 more source

Behavioral Abnormalities, Cognitive Impairments, Synaptic Deficits, and Gene Replacement Therapy in a CRISPR Engineered Rat Model of 5p15.2 Deletion Associated With Cri du Chat Syndrome

Advanced Science, Volume 12, Issue 14, April 10, 2025.
A new CdCS rat model is developed using CRISPR‐Cas9 technology. It shows impairments in cognitive and social behaviors, neuronal dendrite abnormalities in the hippocampus and mPFC, and inflammatory and immune processes in mPFC brain cells. Early AAV‐Ctnnd2 gene therapy enhances cognitive function in CdCS rats.
Jingjing Shen, Yan Wang, Yang Liu, Junying Lan, Shuang Long, Yingbo Li, Di Chen, Peng Yu, Jing Zhao, Yongjun Wang, Shali Wang, Feng Yang   +11 more
wiley   +1 more source

Spontaneous and X-ray-induced chromosomal aberrations in Werner syndrome cells detected by FISH using chromosome-specific painting probes [PDF]

, 2000
M. Grigorova
openalex   +1 more source

A Novel tRF, HCETSR, Derived From tRNA‐Glu/TTC, Inhibits HCC Malignancy by Regulating the SPBTN1‐catenin Complex Axis

Advanced Science, Volume 12, Issue 13, April 3, 2025.
HCETSR, derived from tRNA‐Glu/TTC, binds to SPTBN1, promoting the dissociation of SPTBN1 from the catenin complex and facilitating the translocation of the catenin complex from the cell membrane to the nucleus. Meanwhile, HCETSR reduces proteasomal degradation of β‐catenin and synthesis of nascent β‐catenin.
Tao Rui, Kangbei Zhu, Zonglei Mao, Jiaping Wu, Yi Pan, Qianwei Ye, Cong Chen, Aizhai Xiang, Jufeng Guo, Ning Tang, Jing Zhang, Shusen Zheng, Jian Liu, Xiao Xu   +13 more
wiley   +1 more source