Results 251 to 260 of about 840,795 (338)

The anatomy of a nucleus: As revealed by chromosome painting

PLOS Genetics, 2018
R. Scott Hawley, R. Scott Hawley, Brian D. Slaughter   +2 more
openaire   +4 more sources

Detection of genetic imbalances in tumor genomes by fluorescence in situ hybridization with tumor genomic DNA and subregional DNA probes [PDF]

, 1993
Cremer, Thomas, Jauch, Anna, Joos, Stefan, Lengauer, Christoph, Lichter, Peter, Manoir, Stanislas du, Natarajan, Adayapalam T., Obe, Günter, Popp, Susanne, Ried, Thomas, Scherthan, Harry, Schröck, Evelin, Speicher, Michael R.   +12 more
core   +1 more source

MeCP2 Lactylation Protects against Ischemic Brain Injury by Transcriptionally Regulating Neuronal Apoptosis

Advanced Science, EarlyView.
MeCP2 lactylation protects against ischemic stroke by reducing brain infarct volume and improving neurological outcomes. Lactylation at K210/K249 exerts neuroprotective effects by repressing the transcription of apoptosis‐associated genes, including Pdcd4 and Pla2g6. HDAC3 and p300 serve as key regulatory enzymes for MeCP2 lactylation following stroke.
Min Sun, Yuxin Zhang, Rui Mao, Yan Chen, Pinyi Liu, Lei Ye, Siyi Xu, Junqiu Jia, Shu Shu, Huiya Li, Yanping Yin, Shengnan Xia, Yanting Chen, Yun Xu   +13 more
wiley   +1 more source

Enhancer Extrachromosomal Circular DNA ANKRD28 Elicits Drug Resistance via POU2F2‐Mediated Transcriptional Network in Multiple Myeloma

Advanced Science, EarlyView.
Enhancer eccANKRD28‐manipulated MM cells have been demonstrated to facilitate drug resistance and promote MM progression by activating the key transcription factor, POU2F2. POU2F2 interacts with sequence‐specific eccANKRD28 as well as RUNX1 and RUNX2 motifs to form the protein complex, which activates the promoter of oncogenes (IRF4, JUNB, IKZF3, et al.
Binzhen Chen, Jia Liu, Yaoxin Zhang, Changming Shi, Di Zhu, Guoqiang Zhang, Fei Xiao, Lu Zhong, Minyue Zhang, Lai Guan Ng, Honghui Huang, Tingting Lu, Jian Hou   +12 more
wiley   +1 more source

Single‐Cell Analysis Clarifies Pathological Heterogeneity in Tenosynovial Giant Cell Tumor and Identifies Biomarkers for Predicting Disease Recurrence

Advanced Science, EarlyView.
MP3 tumor cells, a specific subpopulation of tumor cells in D‐TGCT, regulated the differentiation of CD34+ Fbs into MMP3+ Fbs and APOE+ Fbs through COL6A3 − (ITGAV + ITGB8) interaction. APOE+ Fbs activated IL‐1B+CCL20+ Mφs through the CXCL12/CXCR4 axis. IL‐1B+CCL20+ Mφs and MMP3+ Fbs participated in the local invasion of D‐TGCT.
Yubin Xie, Chen Chen, Fei Wu, Yiman Peng, Jing Su, Yang Zhao, Hongjie Huang, Zhong Alan Li, Yin Pei, Wencui Li, Yi He, Tianchen Xue, Chenxi Cao, Sui Peng, Xin Zhang, Weidong Song   +15 more
wiley   +1 more source

The analysis of chromosomal instability in 18 tumor patients with strong acute and/or late side effects by G2-aberration assay and/or whole chromosome painting [PDF]

, 2001
U. Oppitz, Marianne Volleth, Jörn Wulf, G. Bollmann, Thomas Liehr, M. Flentje, Markus Stümm   +6 more
openalex   +1 more source

The Hypoxia‐Associated High‐Risk Cell Subpopulation Distinctly Enhances the Progression of Glioma

Advanced Science, Volume 12, Issue 17, May 8, 2025.
This study suggests the potential roles of a novel hypoxia‐associated CDC20+KIF20A+PTTG1+ cell subpopulation in glioma progression. This high‐risk glioma cell subpopulation is therapeutically vulnerable to glioma progression and may play important roles in glioma standard‐of‐care therapeutic resistance.
Quan Wan, Xuechao Wu, Jinxu Zhou, Weiqi Wu, Yuanliang Cao, Cuiping Sun, Zheng Li, Zhicheng Gong, Hong Tang, Qilin Li, Junsheng Chu, Qing Wang, Kaisa Cui, Xiaojie Lu   +13 more
wiley   +1 more source

Male Mouse Recombination Maps for Each Autosome Identified by Chromosome Painting [PDF]

, 2002
Lutz Froenicke, Lorinda K. Anderson, Johannes Wienberg, Terry Ashley   +3 more
openalex   +1 more source

Global Protein Interactome Mapping in Rice Using Barcode‐Indexed PCR Coupled with HiFi Long‐Read Sequencing

Advanced Science, Volume 12, Issue 11, March 20, 2025.
BIP‐seq is developed, a cost‐effective pipeline for high‐throughput protein–protein interaction (PPI) identification using yeast two‐hybrid system. BIP‐seq successfully map over 15 000 high‐confidence rice PPIs (≈62.5% could be verified by BiFC) within 2 months.
Xixi Liu, Dandan Xia, Jinjin Luo, Mengyuan Li, Lijuan Chen, Yiting Chen, Jie Huang, Yanan Li, Huayu Xu, Yang Yuan, Yu Cheng, Zhiyong Li, Guanghao Li, Shiyi Wang, Xinyong Liu, Wanning Liu, Fengyong Zhang, Zhichao Liu, Xiaohong Tong, Yuxuan Hou, Yifeng Wang, Jiezheng Ying, Abdullaev Mirtemir Baxodir ugli, Mukhammadjon Arabboevich Ergashev, Sanqiang Zhang, Wenya Yuan, Dawei Xue, Jianwei Zhang, Jian Zhang   +28 more
wiley   +1 more source

Analysis of chromosomes in molecular tumor and radiation cytogenetics: Approaches, apllications, perspectives [PDF]

, 1992
Cremer, Christoph, Cremer, Thomas
core