Results 261 to 270 of about 840,795 (338)

Microdissection and Reverse Painting. Reevaluation of Three Cases with Structural Abnormalities in Chromosome 13 [PDF]

, 2002
Ursula Friedrich
openalex   +1 more source

Chromosome Painting

, 2018
A. Lambert, V. M. Pina, E. Schertzer
semanticscholar   +1 more source

Model‐Guided Rational Construction of Escherichia coli Synthetic Consortia for Enhanced 2‐Methylbutyric Acid Production

Advanced Science, EarlyView.
We developed a citramalate‐derived pathway for 2‐methylbutyric acid production in E. coli mono‐culture and consortia. The optimized consortium, using 2‐keto‐3‐methylvalerate as a node, achieved 1817.03 ± 103.73 mg L−1 2‐methylbutyric acid, a 28‐fold increase from the initial strain, with a yield of 0.091 g/g glucose.
Yu Liu, Boyuan Xue, Shaojie Wang, Haijia Su   +3 more
wiley   +1 more source

Reciprocal chromosome painting among human, aardvark, and elephant (superorder Afrotheria) reveals the likely eutherian ancestral karyotype [PDF]

, 2003
Fengtang Yang, Elena Alkalaeva, Polina L. Perelman, Amanda T. Pardini, Wilbur R. Harrison, Patrícia C. M. O’Brien, Beiyuan Fu, Alexander S. Graphodatsky, M.A. Ferguson‐Smith, Terence J. Robinson   +9 more
openalex   +1 more source

Identification and Biological Evaluation of a Novel CLK4 Inhibitor Targeting Alternative Splicing in Pancreatic Cancer Using Structure‐Based Virtual Screening

Advanced Science, EarlyView.
Pancreatic cancer is a highly aggressive malignancy with limited treatment options. CLK4 regulates alternative splicing, contributing to cancer progression. This study establishes a computational model to identify CLK4 inhibitors, leading to compound 150441 (IC50: 21.4 nm).
Chun‐Lin Yang, Yi‐Wen Wu, Huang‐Ju Tu, Yun‐Hsuan Yeh, Tony Eight Lin, Tzu‐Ying Sung, Mu‐Chun Li, Shih‐Chung Yen, Jui‐Hua Hsieh, Ming‐Chin Yu, Sen‐Yung Hsieh, Hsing‐Pang Hsieh, Shiow‐Lin Pan, Kai‐Cheng Hsu   +13 more
wiley   +1 more source

Wnt Inhibition Safeguards Porcine Embryonic Stem Cells From the Acquisition of Extraembryonic Endoderm Cell Fates

Advanced Science, Volume 12, Issue 17, May 8, 2025.
The study reports that Wnt inhibitors safeguard porcine embryonic stem cells (ESCs) from acquiring the extraembryonic endoderm (XEN) lineage, and further develop an efficient strategy to derive XEN cells from ESCs. The XEN cells from ESCs exhibit similar transcriptome and chromatin accessibility features to XEN cells from embryos and contribute to ...
Hanning Wang, Liang Zhong, Zhuangfei Wang, Jinzhu Xiang, Duanqing Pei   +4 more
wiley   +1 more source

Whole‐chromosome oligo‐painting in licorice unveils interspecific chromosomal evolutionary relationships and possible origin of triploid genome species [PDF]

Zhuang Meng, Qian Zheng, Shandang Shi, Wei Wang, Fei Wang, Quanliang Xie, Xifeng Chen, Haitao Shen, Guanghui Xiao, Hongbin Li   +9 more
openalex   +1 more source

Sequential multiple probe fluorescence in-situ hybridization analysis of human oocytes and polar bodies by combining centromeric labelling and whole chromosome painting [PDF]

, 2003
T. Anahory
openalex   +1 more source

Manipulation of Oxygen Tension in Damaged Regions via Hypoxia‐Induced IPN Hydrogel Microspheres for Intervertebral Disc Regeneration

Advanced Science, EarlyView.
A novel interpenetrating network hydrogel microsphere (NSC‐Exos@HIMS) is developed to manipulate oxygen tension in damaged regions and recruit endogenous stem cells. In vitro and in vivo results show that NSC‐Exos@HIMS maintains the hypoxia microenvironment for up to 5 days, which triggers nucleus pulposus cell‐like differentiation and enhanced ECM ...
Xingdie Zhou, Zhendong Lv, Zehao Chen, Yiming Xu, Chao Lin, Li Liu, Hao Chen, Bing Niu, Wenguo Cui, Yuhui Zhang   +9 more
wiley   +1 more source

OligoY pipeline for full Y chromosome painting [PDF]

Isabela Almeida, Henry Bonilla, Mara Pinheiro, Antonio Bernardo Carvalho, Maria D. Vibranovski   +4 more
openalex   +1 more source