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Ki-67 acts as a biological surfactant to disperse mitotic chromosomes
Eukaryotic genomes are partitioned into chromosomes that form compact and spatially well-separated mechanical bodies during mitosis. This enables chromosomes to move independently of each other for segregation of precisely one copy of the genome to each ...
Antonio Z Politi+2 more
exaly +2 more sources
Numerous Transitions of Sex Chromosomes in Diptera
Many species groups, including mammals and many insects, determine sex using heteromorphic sex chromosomes. Diptera flies, which include the model Drosophila melanogaster, generally have XY sex chromosomes and a conserved karyotype consisting of six ...
Beatriz Vicoso, Doris Bachtrog
exaly +2 more sources
Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators
The human X and Y chromosomes evolved from an ordinary pair of autosomes, but millions of years ago genetic decay ravaged the Y chromosome, and only three per cent of its ancestral genes survived. We reconstructed the evolution of the Y chromosome across
Daniel W Bellott+2 more
exaly +2 more sources
The Number of X Chromosomes Causes Sex Differences in Adiposity in Mice
Sexual dimorphism in body weight, fat distribution, and metabolic disease has been attributed largely to differential effects of male and female gonadal hormones. Here, we report that the number of X chromosomes within cells also contributes to these sex
Arthur P Arnold, Karen Reue
exaly +2 more sources
Telomeres: protecting chromosomes against genome instability
Jan Karlseder
exaly +2 more sources
The Profile of MicroRNA Expression in Bone Marrow in Non-Hodgkin’s Lymphomas
Non-Hodgkin’s lymphomas (NHLs) are a heterogeneous group of malignant lymphomas that can occur in both lymph nodes and extranodal sites. Bone marrow (BM) is the most common site of extranodal involvement in NHL.
Yuliya A. Veryaskina+4 more
doaj +1 more source
Variability of chromosome number and morphology and gymnosperm improvement [PDF]
The causes of monotypic and polytypic variability of the gymnosperm chromosome complex were studied. The development of karyogram and idiograms of the species should be applied in the aim of upgrading the breeding method and technique.
Tucović Aleksandar+2 more
doaj +1 more source
The miRNA Profile in Non-Hodgkin’s Lymphoma Patients with Secondary Myelodysplasia
Myelodysplastic syndromes are a group of clonal diseases of hematopoietic stem cells and are characterized by multilineage dysplasia, ineffective hematopoiesis, peripheral blood cytopenias, genetic instability and a risk of transformation to acute ...
Yuliya Andreevna Veryaskina+4 more
doaj +1 more source
Evaluation of Genotoxic and Cytotoxic Effects of Gluten in Male Albino Mice
Gluten is a protein commonly found in daily diets in the form of wheat, barley, rye, and other grains. It serves as the structural component in flour, providing the binding qualities that maintain the shape and texture of food items.
Nagla Z. El-Alfy+3 more
doaj +1 more source
Prognostic Markers of Myelodysplastic Syndromes
Myelodysplastic syndrome (MDS) is a clonal disease characterized by multilineage dysplasia, peripheral blood cytopenias, and a high risk of transformation to acute myeloid leukemia.
Yuliya Andreevna Veryaskina+4 more
doaj +1 more source