Results 1 to 10 of about 1,530,143 (402)

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes

Nature, 2016
Eukaryotic genomes are partitioned into chromosomes that form compact and spatially well-separated mechanical bodies during mitosis. This enables chromosomes to move independently of each other for segregation of precisely one copy of the genome to each ...
Antonio Z Politi, Thomas Müller-reichert, Ina Poser   +2 more
exaly   +2 more sources

How to identify sex chromosomes and their turnover

Molecular Ecology, 2019
Although sex is a fundamental component of eukaryotic reproduction, the genetic systems that control sex determination are highly variable. In many organisms the presence of sex chromosomes is associated with female or male development.
Alison E Wright, Thea F Rogers, Daniela H Palmer   +2 more
exaly   +2 more sources

The miRNA Profile in Non-Hodgkin’s Lymphoma Patients with Secondary Myelodysplasia

Cells, 2020
Myelodysplastic syndromes are a group of clonal diseases of hematopoietic stem cells and are characterized by multilineage dysplasia, ineffective hematopoiesis, peripheral blood cytopenias, genetic instability and a risk of transformation to acute ...
Yuliya Andreevna Veryaskina, Sergei Evgenievich Titov, Igor Borisovich Kovynev, Tatiana Ivanovna Pospelova, Igor Fyodorovich Zhimulev   +4 more
doaj   +1 more source

Prognostic Markers of Myelodysplastic Syndromes

Medicina, 2020
Myelodysplastic syndrome (MDS) is a clonal disease characterized by multilineage dysplasia, peripheral blood cytopenias, and a high risk of transformation to acute myeloid leukemia.
Yuliya Andreevna Veryaskina, Sergei Evgenievich Titov, Igor Borisovich Kovynev, Tatiana Ivanovna Pospelova, Igor Fyodorovich Zhimulev   +4 more
doaj   +1 more source

The "Gene" of success: what national high-growth firms can teach Russian business in modern conditions

π-Economy, 2022
Nowadays, there is an increasing value in analyzing and transferring the successful experience of the work of national companies that succeed and stay successful in the face of external shocks, high uncertainty and the intensification of new challenges ...
Pletnev Dmitri, Kozlova Elena, Naumova Kseniia   +2 more
doaj   +1 more source

Down syndrome associated childhood myeloid leukemia with yet unreported acquired chromosomal abnormalities and a new potential adverse marker: dup(1)(q25q44)

Molecular Cytogenetics, 2018
Background Children with constitutional trisomy 21, i.e. Down syndrome (DS, OMIM #190685) have a 10 to 20-fold increased risk for a hematopoietic malignancy. They may suffer from acute lymphoblastic leukemia or acute myeloid leukemia (AML).
Faten Moassass, Abdulsamad Wafa, Thomas Liehr, Ayman Al-Ablog, Walid AL Achkar   +4 more
doaj   +1 more source

Sorting of chromosomes by magnetic separation [PDF]

, 1988
Chromosomes were isolated from Chinese hamster x human hybrid cell lines containing four and nine human chromosomes. Human genomic DNA was biotinylated by nick translation and used to label the human chromosomes by in situ hybridization in suspension ...
A Oberteufer, B Schw�ger, B Trask, C Cremer, Christoph Cremer, CS Owen, D Durnam, D Peters, D Pinkel, D Pinkel, Eduardo Diaz, Ernst W. Steegmayer, G Dudin, Gertrud Dudin, Haide Schnitzer, JC Fuscoe, JG Collard, K Nustad, Kathryn E. Howell, KE Howell, L Manuelidis, L-C Yu, M Schardin, Peter Vogt, PW Rigby, RS Molday, RV Lebo, T Lea, T Lea, Thomas Cremer, U Blochmann   +30 more
core   +1 more source

No evidence for genetic sex determination in Daphnia magna

Royal Society Open Science, 2021
Mechanisms of sex determination (SD) differ widely across the tree of life. In genotypic sex determination (GSD), genetic elements determine whether individuals are male or female, while in environmental sex determination (ESD), external cues control the
Luca Cornetti, Dieter Ebert
doaj   +1 more source

HIM-10 is required for kinetochore structure and function on Caenorhabditis elegans holocentric chromosomes. [PDF]

, 2001
Macromolecular structures called kinetochores attach and move chromosomes within the spindle during chromosome segregation. Using electron microscopy, we identified a structure on the holocentric mitotic and meiotic chromosomes of Caenorhabditis elegans ...
Albertson, Albertson, Albertson, Amon, Buchwitz, Dernburg, Fire, Gonczy, Harlow, Heald, Hedgecock, Hodgkin, Howman, Kainta, Kimble, Lombillo, Maney, McDonald, McEwen, Mello, Moore, Nabetani, Newman, Nicklas, O'Connell, Rappleye, Roos, Savoian, Shah, Sharp, Sharp, Wigge, Yanagida, Yao   +33 more
core   +2 more sources

The Emerging Role of the Cytoskeleton in Chromosome Dynamics

Frontiers in Genetics, 2017
Chromosomes underlie a dynamic organization that fulfills functional roles in processes like transcription, DNA repair, nuclear envelope stability, and cell division.
Maya Spichal, Emmanuelle Fabre
doaj   +1 more source