Results 1 to 10 of about 1,199,530 (311)
Ki-67 acts as a biological surfactant to disperse mitotic chromosomes
Nature, 2016 Eukaryotic genomes are partitioned into chromosomes that form compact and spatially well-separated mechanical bodies during mitosis. This enables chromosomes to move independently of each other for segregation of precisely one copy of the genome to each ...
Antonio Z Politi +2 more
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Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators
Nature, 2014 The human X and Y chromosomes evolved from an ordinary pair of autosomes, but millions of years ago genetic decay ravaged the Y chromosome, and only three per cent of its ancestral genes survived. We reconstructed the evolution of the Y chromosome across
Daniel W Bellott +2 more
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DNA methylation profiling of human chromosomes 6, 20 and 22
Nature Genetics, 2006 DNA methylation is the most stable type of epigenetic modification modulating the transcriptional plasticity of mammalian genomes. Using bisulfite DNA sequencing, we report high-resolution methylation profiles of human chromosomes 6, 20 and 22, providing
Rene Cortese, Kevin L Howe, Stephan Beck
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Telomeres: protecting chromosomes against genome instability
Nature Reviews Molecular Cell Biology, 2010 Jan Karlseder
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NOMENCLATURE FOR CENTROMERIC POSITION ON CHROMOSOMES
, 2009 N the inorphologic identification of chromosomes, the location of the I centromere is the most useful landmark, and one which is characterized by great constancy. It would seem that not much could be added to the definitions by E. B. WILSON (1928) of the
A. Levan, K. Fredga, A. Sandberg
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DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae
Nature, 2000 Here we determine the complete genomic sequence of the Gram negative, γ-Proteobacterium Vibrio cholerae El Tor N16961 to be 4,033,460 base pairs (bp). The genome consists of two circular chromosomes of 2,961,146 bp and 1,072,314 bp that together encode 3,
J. Heidelberg +31 more
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How to identify sex chromosomes and their turnover
Molecular Ecology, 2019 Although sex is a fundamental component of eukaryotic reproduction, the genetic systems that control sex determination are highly variable. In many organisms the presence of sex chromosomes is associated with female or male development.
Daniela H. Palmer +3 more
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Genetic Diversity on the Sex Chromosomes
Genome Biology and Evolution, 2018 Levels and patterns of genetic diversity can provide insights into a population’s history. In species with sex chromosomes, differences between genomic regions with unique inheritance patterns can be used to distinguish between different sets of possible
Melissa A. Wilson Sayres
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Molecular Systems Biology, 2015 Mammalian chromosomes fold into arrays of megabase‐sized topologically associating domains (TADs), which are arranged into compartments spanning multiple megabases of genomic DNA.
J. Fraser +21 more
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Numerous Transitions of Sex Chromosomes in Diptera
PLoS Biology, 2015 Many species groups, including mammals and many insects, determine sex using heteromorphic sex chromosomes. Diptera flies, which include the model Drosophila melanogaster, generally have XY sex chromosomes and a conserved karyotype consisting of six ...
Beatriz Viçoso, D. Bachtrog
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