Results 1 to 10 of about 892,112 (356)

The Profile of MicroRNA Expression in Bone Marrow in Non-Hodgkin’s Lymphomas

open access: yesDiagnostics, 2022
Non-Hodgkin’s lymphomas (NHLs) are a heterogeneous group of malignant lymphomas that can occur in both lymph nodes and extranodal sites. Bone marrow (BM) is the most common site of extranodal involvement in NHL.
Yuliya A. Veryaskina   +4 more
doaj   +1 more source

Selection of optimal bioinformatic tools and proper reference for reducing the alignment error in targeted sequencing data

open access: yesJournal of Medical Signals and Sensors, 2021
Background: Careful design in the primary steps of a next-generation sequencing study is critical for obtaining successful results in downstream analysis.
Hannane Mohammadi Nodehi   +2 more
doaj   +1 more source

Cytogenetic abnormalities in patients with hematological malignancies in Lahore city, Pakistan

open access: yesBrazilian Journal of Biology, 2021
Hematological and hematopoietic cells malignancies of the genes and hematopoietic cells are associated with the genetic mutation, often at the chromosomal level.
U. A. Awan   +10 more
doaj   +1 more source

The miRNA Profile in Non-Hodgkin’s Lymphoma Patients with Secondary Myelodysplasia

open access: yesCells, 2020
Myelodysplastic syndromes are a group of clonal diseases of hematopoietic stem cells and are characterized by multilineage dysplasia, ineffective hematopoiesis, peripheral blood cytopenias, genetic instability and a risk of transformation to acute ...
Yuliya Andreevna Veryaskina   +4 more
doaj   +1 more source

Adding New Pieces to the Puzzle of Karyotype Evolution in Harttia (Siluriformes, Loricariidae): Investigation of Amazonian Species

open access: yesBiology, 2021
A remarkable morphological diversity and karyotype variability can be observed in the Neotropical armored catfish genus Harttia. These fishes offer a useful model to explore both the evolution of karyotypes and sex chromosomes, since many species possess
Francisco de M. C. Sassi   +10 more
doaj   +1 more source

Prognostic Markers of Myelodysplastic Syndromes

open access: yesMedicina, 2020
Myelodysplastic syndrome (MDS) is a clonal disease characterized by multilineage dysplasia, peripheral blood cytopenias, and a high risk of transformation to acute myeloid leukemia.
Yuliya Andreevna Veryaskina   +4 more
doaj   +1 more source

Down syndrome associated childhood myeloid leukemia with yet unreported acquired chromosomal abnormalities and a new potential adverse marker: dup(1)(q25q44)

open access: yesMolecular Cytogenetics, 2018
Background Children with constitutional trisomy 21, i.e. Down syndrome (DS, OMIM #190685) have a 10 to 20-fold increased risk for a hematopoietic malignancy. They may suffer from acute lymphoblastic leukemia or acute myeloid leukemia (AML).
Faten Moassass   +4 more
doaj   +1 more source

Sorting of chromosomes by magnetic separation [PDF]

open access: yes, 1988
Chromosomes were isolated from Chinese hamster x human hybrid cell lines containing four and nine human chromosomes. Human genomic DNA was biotinylated by nick translation and used to label the human chromosomes by in situ hybridization in suspension ...
A Oberteufer   +30 more
core   +1 more source

HIM-10 is required for kinetochore structure and function on Caenorhabditis elegans holocentric chromosomes. [PDF]

open access: yes, 2001
Macromolecular structures called kinetochores attach and move chromosomes within the spindle during chromosome segregation. Using electron microscopy, we identified a structure on the holocentric mitotic and meiotic chromosomes of Caenorhabditis elegans ...
Albertson   +33 more
core   +2 more sources

The Emerging Role of the Cytoskeleton in Chromosome Dynamics

open access: yesFrontiers in Genetics, 2017
Chromosomes underlie a dynamic organization that fulfills functional roles in processes like transcription, DNA repair, nuclear envelope stability, and cell division.
Maya Spichal, Emmanuelle Fabre
doaj   +1 more source

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