Results 101 to 110 of about 1,037,337 (302)

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

Advanced Science, EarlyView.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang, Yu Geng, Xinyu Guo, Chen Wang, Yongjing Sun, Luqi Liu, Li Liu, QianQian Gao, XinFang Zhu, Hongxiang Cao, Gengshuo Zhang, Yunxia Liu, Guobin Zhang, Baoyin Chen, Jinfei Zhang, Xin Hou, Xiaoming Li, Dajian Zhang   +17 more
wiley   +1 more source

A checkpoint control orchestrates the replication of the two chromosomes of Vibrio cholerae. [PDF]

, 2016
International audienceBacteria with multiple chromosomes represent up to 10% of all bacterial species. Unlike eukaryotes, these bacteria use chromosome-specific initiators for their replication.
Mazel, Didier, Kennedy, Sean P., Possoz, Christophe, Martins, Francisco de Lemos, Marbouty, Martial, de Lemos Martins, Francisco, Koszul, Romain, Val, Marie-Eve, Kemble, Harry, Skovgaard, Ole, Kennedy, Sean P, Bland, Michael J   +11 more
core   +1 more source

An Artificially Selected Cytokinin‐Pathway Transcription Factor Balances Soybean Yield and Pathogen Resistance

Advanced Science, EarlyView.
A cytokinin pathway transcription factor, RR2b, was artificially selected during soybean domestication and improvement based on its differential transcriptional activity, which correlates with ATT repeat polymorphisms in its promoter. RR2b balances yield and defense by fine‐tuning its expression level and offers a promising target for decoupling trade ...
Qun Ma, Yaqing Chen, Yiwen Gao, Xueting Hu, Qun Yang, Yucheng Liu, Peiyong Xin, Jijun Yan, Jinfang Chu, Lei Li, Zhixi Tian, Bo Ren   +11 more
wiley   +1 more source

Genetic and cytological analyses reveal the recombination landscape of a partially differentiated plant sex chromosome in kiwifruit

BMC Plant Biology, 2019
Background Angiosperm sex chromosomes, where present, are generally recently evolved. The key step in initiating the development of sex chromosomes from autosomes is the establishment of a sex-determining locus within a region of non-recombination.
S. M. Pilkington, J. Tahir, E. Hilario, S. E. Gardiner, D. Chagné, A. Catanach, J. McCallum, L. Jesson, L. G. Fraser, M. A. McNeilage, C. Deng, R. N. Crowhurst, P. M. Datson, Q. Zhang   +13 more
doaj   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila

Advanced Science, EarlyView.
While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li, Haimin Chen, Gangqi Fang, Dongxiang Wei, Hongyun Wu, Chen Chen, Song Hong, Chengshu Wang   +7 more
wiley   +1 more source

A conserved mechanism drives partition complex assembly on bacterial chromosomes and plasmids

Molecular Systems Biology, 2018
Chromosome and plasmid segregation in bacteria are mostly driven by ParABS systems. These DNA partitioning machineries rely on large nucleoprotein complexes assembled on centromere sites (parS).
Roxanne E Debaugny, Aurore Sanchez, Jérôme Rech, Delphine Labourdette, Jérôme Dorignac, Frédéric Geniet, John Palmeri, Andrea Parmeggiani, François Boudsocq, Véronique Anton Leberre, Jean‐Charles Walter, Jean‐Yves Bouet   +11 more
doaj   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module

Advanced Science, EarlyView.
Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang, Jiale Qi, Lin Wei, Qin Yu, Zhongyuan Liu, Lianyang Bai, Lang Pan   +6 more
wiley   +1 more source

Optical mapping as a routine tool for bacterial genome sequence finishing [PDF]

, 2007
Background: In sequencing the genomes of two Xenorhabdus species, we encountered a large number of sequence repeats and assembly anomalies that stalled finishing efforts.
Norton, S., Miller, N., Zijin Du, Goldman, Barry S., Latreille Phil, Bode, Helge Björn, Henkhaus John, Forst, Steve, John Henkhaus, Goodrich-Blair, H., Miller, Nancy, Slater Steven, Stacie Norton, Bode, H., Goldman Barry S, Henkhaus, J., Gaudriault, S., Steve Forst, Creg Darby, Gaudriault Sophie, Darby Creg, Goldman, B., Gaudriault, Sophie, Darby, C., Du, Z., Goodner, B., Norton, Stacie, Sophie Gaudriault, Miller Nancy, Goodrich-Blair, Heidi, Henkhaus, John, Heidi Goodrich-Blair, Gaudriault, Sophie, S., Latreille, Phil, Slater, S., Goodrich-Blair Heidi, Goodner, Brad, Goodner Brad, Latreille, P., Bode, Helge B., Nancy Miller, Norton Stacie, Brad Barbazuk, Phil Latreille, Steven Slater, Slater, Steven, Forst Steve, Helge B Bode, Forst, S., Barbazuk, Brad, Barbazuk Brad, Du, Zijin, Bode Helge B, Barry S Goldman, Du Zijin, Brad Goodner, Barbazuk, B., Darby, Creg   +57 more
core   +1 more source