Rapid assembly of functional modules for generating human artificial chromosome constructs compatible with epigenetic centromere seeding. [PDF]
Birchak GJ +5 more
europepmc +1 more source
Hox Gene Variation Drives Morphological Specialization of Humpback Grouper Cromileptes altivelis
Cromileptes altivelis exhibits a distinctive “sunken head and humpback” morphology, formed through cranial remodeling. Genetic analyses identified unique amino acid variants in Hoxa7a and Hoxa10b, with functional tests confirming their role in enhancing osteoblast activity and driving cranial remodeling.
Xiaoying Cao +4 more
wiley +1 more source
Exploiting fuzzy weights in CNN model-based taxonomic classification of 500-bp sequence bacterial dataset. [PDF]
Algarni AD +6 more
europepmc +1 more source
Exposures in Indoor Air Affecting Health
ABSTRACT Indoor air quality (IAQ) is influenced by a wide range of chemical, biological and physical agents that can negatively impact physical, immunological and mental health. Adverse health effects depend on the type and concentration of pollutants, duration of exposure, and individual susceptibility.
Maria Hartiala +38 more
wiley +1 more source
Pioneer of bacterial genetics: the legacy of Esther Miriam Lederberg. [PDF]
Wendling CC, Bailey ZM.
europepmc +1 more source
Luteinizing hormone receptor knockout mouse: What has it taught us?
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley +1 more source
Chromosome architecture affects virulence and competitiveness in <i>Agrobacterium tumefaciens</i> C58. [PDF]
Aliu E +8 more
europepmc +1 more source
In this study of 1 126 059 pregnancies, we find evidence of comparable predictive ability for adverse perinatal outcomes across four fetal growth references, but with notable differences in sensitivity and false positive rate (FPR). The WHO reference demonstrated balanced performance in detecting at‐risk fetuses, suggesting its suitability for clinical
Linda Lindström +6 more
wiley +1 more source
Genome-Wide Association Analysis and Breeding-Oriented SNP Marker Development for Bacterial Wilt Resistance in Tomato (<i>Solanum lycopersicum</i> L.). [PDF]
Bhunchoth A +14 more
europepmc +1 more source
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry +27 more
wiley +1 more source

