Results 251 to 260 of about 1,205,521 (283)

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Chronic Myeloid Leukemia Harboring a Novel Four-Way Variant Translocation t(7;22;9;15)(p15;q11.2;q34.1;q22) With Cryptic Double Philadelphia Chromosomes. [PDF]

Cureus
Kamigaki S, Ito M, Nakano S, Takagi N.
europepmc   +1 more source

Targeted Extracellular Vesicles Deliver Asiaticoside to Inhibit AURKB/DRP1‐Mediated Mitochondrial Fission and Attenuate Hypertrophic Scar Formation

Advanced Science, EarlyView.
Hypertrophic scar formation is driven by excessive mitochondrial fission in wound macrophages, which we discover is governed by a novel AURKB‐DRP1(Ser616) axis. The study develops a targeted therapy using cRGD‐decorated extracellular vesicles to deliver the natural compound Asiaticoside specifically to macrophages.
Luyu Li, Chenli Si, Xue Wang, Xiaojin Wu, Ying Shang, Shengfang Ge, Yong Wang, Yong Zuo, Zhen Zhang   +8 more
wiley   +1 more source

Clinical validation of artificial intelligence-assisted karyotyping on peripheral blood in a cytogenetic diagnostic laboratory. [PDF]

Hum Genet
Zhu Y, Chau MHK, Wang H, Song N, Wei R, Suen KW, Chan ACS, Hung WC, Cao Y, Dong Z, Leung TY, Cheung SW, Choy KW.   +12 more
europepmc   +1 more source

CENP-E initiates chromosome congression by opposing Aurora kinases to promote end-on attachments. [PDF]

Nat Commun
Vukušić K, Tolić IM.
europepmc   +1 more source

Identification of a complex chromosomal insertion using the chromosome conformation based karyotyping technique for the implementation of PGT-SR. [PDF]

BMC Genomics
Zheng T, Cheng D, Yang Y, Lu S, Li H, Xie L, Li Q, Ye H.   +7 more
europepmc   +1 more source

Adipose-derived mesenchymal stem cells from solid tissue and lipoaspirates: A comparative study of phenotype, growth, and secretome. [PDF]

World J Stem Cells
Dam PTM, Nguyen DD, Ngo ATT, Tran AM, Nguyen TT, Nguyen PV, Nguyen CQ, Nguyen ATT, Pham QT, Than UTT.   +9 more
europepmc   +1 more source

Kinetochore-centrosome feedback linking CENP-E and Aurora kinases controls chromosome congression. [PDF]

Nat Commun
Vukušić K, Tolić IM.
europepmc   +1 more source