Results 181 to 190 of about 71,445,035 (215)

LAWS-HiC: A Locally Adaptive Weighting and Screening (LAWS) Approach to Improve Detection of Long-Range Chromatin Interactions from Hi-C Data. [PDF]

Methods Protoc
Zhou L, Chen C, Zhao JZ, Hu M, Li Y.
europepmc   +1 more source

Metastasis Pattern‐Specific Biomarkers and Therapeutic Targets in Gastric Cancer: From Surgical Specimens to Clinical Translation

Annals of Gastroenterological Surgery, EarlyView.
Gastric cancer metastasis should be considered according to its anatomical route, because lymphatic, peritoneal, and hematogenous dissemination involve partly distinct molecular mechanisms. This review summarizes metastasis pattern‐associated and pattern‐specific molecules identified using surgical specimens, evaluates their evidence and translational ...
Mitsuro Kanda
wiley   +1 more source

Polar chromosomes are rescued from missegregation by spindle elongation-driven microtubule pivoting. [PDF]

Nat Commun
Koprivec I, Štimac V, Đura M, Vukušić K, Mikec P, Tolić IM.   +5 more
europepmc   +1 more source

Distinct Consequences of BCOR and BCORL1 Mutations in Myeloid Neoplasms and Bone Marrow Failure

American Journal of Hematology, EarlyView.
ABSTRACT BCOR and BCORL1 (BCOR/L1) mutations are observed in both myeloid neoplasms (MN) and bone marrow failure syndromes (BMF), but their clinical significance may differ. We analyzed 11 340 patients and identified 418 BCOR/L1‐mutated patients, focusing on differences between MN and BMF. Compared with MN, BMF was associated with younger age, a higher
Atsushi Marumo, Arda Durmaz, Christopher Haddad, Aashray Mandala, Felipe de Almeida Sartori, Akram Abushamma, Serhan Unlu, Xiaorong Gu, Zachary Brady, Matteo D'Addona, Kartik Lakhotiya, Luca Guarnera, Masanori Yoshida, Monika M. Toma, Mark D. Orland, Carlos Bravo‐Perez, Carmelo Gurnari, Koichi Takahashi, Tomasz Skorski, Stephan Hutter, Torsten Haferlach, Marcin Wlodarski, Valeria Visconte, Jaroslaw P. Maciejewski   +23 more
wiley   +1 more source

Gene density homogeneity is disrupted by repetitive DNA Expansion. [PDF]

PLoS One
Hu Z, Chien S, Laird K, Blackmon H.
europepmc   +1 more source

L‐Cysteine and N‐Acetylcysteine Supplementation Improves Clinical Outcome in a Patient With COXPD10

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT MTO1 is a nuclear gene that encodes a mitochondrial protein essential for modifying mitochondrial transfer RNAs (tRNAs) and stabilizing codon‐anticodon interactions to ensure accurate and efficient mitochondrial protein synthesis and oxidative phosphorylation.
Nishitha R. Pillai, Sara A. Elsbecker, Grace Bronken McCarthy, Kaitlin Weisshappel, Peter Karachunski, Fernando Scaglia   +5 more
wiley   +1 more source

Cohesin release-factor Wapl modulates axis and chromatin structure to promote conjunction and separation of meiotic chromosomes.

Cell Rep
Zickler D, Rodrigues Neves AR, Kleckner N.   +2 more
europepmc   +1 more source

Mobile genetic elements-driven partitions of mega-plasmids resistome in <i>Salmonella</i> Infantis. [PDF]

Microbiol Spectr
Zhang Y, Chu M, Liao Y-T, Wu VCH.
europepmc   +1 more source

Agro-Morphological and Cytogenetic Characterization of <i>Hibiscus</i> Genetic Resources: Implications for Germplasm Conservation and Interspecific Breeding. [PDF]

Plants (Basel)
Sultan Y, Deepo DM, Lim KB, Norkevičienė E.   +3 more
europepmc   +1 more source