Results 251 to 260 of about 9,449,306 (346)

Combined SNP parental haplotyping and intensity analysis identifies meiotic and mitotic aneuploidies and frequent segmental aneuploidies in preimplantation human embryos. [PDF]

Sci Rep
Handyside AH, Newnham L, Newnham M, Henning D, Velebny J, Pozdena J, Krmelova J, Horak J.   +7 more
europepmc   +1 more source

An evolutionarily conserved early replicatig segment on the sex chromosomes of man and great apes [PDF]

, 1986
Schempp, Werner, Weber, Bernhard, Wiesner, Henning   +2 more
core  

Reference‐Guided Chromosome‐by‐Chromosome de novo Assembly at Scale Using Low‐Coverage High‐Fidelity Long‐Reads with HiFiCCL

Advanced Science, EarlyView.
HiFiCCL, as the first assembly framework specifically designed for low‐coverage high‐fidelity reads, improves the assembly quality of existing assemblers and also enhances downstream applications such as large structural variant (SV) detection (>10 000 bp), synteny analysis, pangenome graph construction, and graph‐based individual‐specific germline SVs
Zhongjun Jiang, Weihua Pan, Runtian Gao, Heng Hu, Wentao Gao, Murong Zhou, Yu‐Hang Yin, Zhipeng Qian, Shuilin Jin, Guohua Wang   +9 more
wiley   +1 more source

KIF18A promotes chromosome congression in cooperation with CENP-E downstream of CENP-C. [PDF]

Cell Rep
Miao J, Hara M, Su KC, Keys HR, Kong W, Takenoshita Y, Cheeseman IM, Fukagawa T.   +7 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Insights on genomic profiles of drug resistance and virulence in a cohort of Leishmania infantum isolates from the Mediterranean area. [PDF]

Parasit Vectors
Carrasco-Martin M, Martí-Carreras J, Gómez-Ponce M, Alcover MM, Roura X, Ferrer L, Baneth G, Bruno F, Chicharro C, Cordeiro-da-Silva A, Cristovão J, Di Muccio T, Maia C, Moreno J, Priego A, Roca-Geronès X, Santarem N, Soriano AV, Vitale F, Yasur-Landau D, Francino O.   +20 more
europepmc   +1 more source

Mapping the Non‐Canonical Splicing Variants: Decrypting the Hidden Genetic Architecture of Idiopathic Male Infertility

Advanced Science, EarlyView.
This study highlights the significance of non‐canonical splicing variants in male infertility, a factor often overlooked during the analysis of high‐throughput sequencing data. Incorporating the non‐canonical splicing variants prioritization in the genetic analysis pipeline will increase the genetic diagnosis of patients with male infertility ...
Kuokuo Li, Yuge Chen, Dongdong Tang, Yuying Sheng, Xu Han, Hao Geng, Na Zhang, Zongliu Duan, Guanxiong Wang, Yang Gao, Rui Guo, Rong Hua, Zhiming Ding, Chuan Xu, Qunshan Shen, Zhen Yu, Bing Song, Mingrong Lv, Yuping Xu, Huan Wu, Ji Wu, Yunxia Cao, Xiaojin He   +22 more
wiley   +1 more source

Crossover interference mediates multiscale patterning along meiotic chromosomes. [PDF]

Nat Commun
White MA, Weiner B, Chu L, Lim G, Prentiss M, Kleckner N.   +5 more
europepmc   +1 more source

EGR Proteins Mediate Interferon‐Independent Anti‐HSV‐1 Responses Through Viral and Host Targets

Advanced Science, EarlyView.
Early antiviral responses are typically mediated by interferons. However, during HSV‐1 infection, host early growth response (Egr) genes, which are not interferon‐stimulated genes, are quickly induced by viral protein ICP0. EGR proteins, in turn, suppress viral lytic infection by activating viral latency‐associated (LAT) and host immune regulatory ...
Shuaishuai Wang, Fujun Hou, Xunuo Jin, Yuhang Xiang, Dongli Pan   +4 more
wiley   +1 more source

CENP-E initiates chromosome congression by opposing Aurora kinases to promote end-on attachments. [PDF]

Nat Commun
Vukušić K, Tolić IM.
europepmc   +1 more source