Results 41 to 50 of about 7,790,467 (300)

Non-random distribution of high density chromatin detected at opposite ends of T-banded human metaphase chromosomes

Genetics and Molecular Biology, 2007
Previous research using microdensitometric scanning and computer graphic image analysis showed that T-banded segments of human metaphase chromosomes usually exhibit an asymmetrical distribution of high density (HD) chromatin between sister chromatids ...
Federico F. Santiñaque, Máximo E. Drets   +1 more
doaj   +1 more source

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo, Melissa Gerstle, Leah Cheng, Richard Cooper, Katherine Coyne, Claire Dusa, Naomi E. Joffe, Diana Schwarz, Sarah Steltz, Akiko Shimamura, Kasiani C. Myers, Thea Quinton   +11 more
wiley   +1 more source

Rapid metaphase and interphase detection of radiation-induced chromosome aberrations in human lymphocytes by chromosomal suppression in situ hybridization [PDF]

, 1990
Chromosomal in situ suppression (CISS)-hybridization of biotinylated phage DNA-library inserts from sorted human chromosomes was used to decorate chromosomes 1 and 7 specifically from pter to qter and to detect structural aberrations of these chromosomes
Cremer, Thomas, Emmerich, Patricia, Cremer, Christoph, Lichter, Peter, Popp, Susanne, P. Lichter, T. Cremer, C. Cremer, S. Popp, P. Emmerich   +9 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Application of the FISH Technique to Visualize Sex Chromosomes in Domestic Cat Spermatozoa

Animals, 2021
Fluorescence in situ hybridization is a molecular cytogenetics technique that enables the visualization of chromosomes in cells via fluorescently labeled molecular probes specific to selected chromosomes.
Barbara Kij-Mitka, Halina Cernohorska, Svatava Kubickova, Sylwia Prochowska, Wojciech Niżański, Joanna Kochan, Monika Bugno-Poniewierska   +6 more
doaj   +1 more source

Non-random chromosome positioning in mammalian sperm nuclei, with migration of the sex chromosomes during late spermatogenesis. [PDF]

, 2005
Chromosomes are highly organized and compartmentalized in cell nuclei. The analysis of their position is a powerful way to monitor genome organization in different cell types and states.
Foster, H, Bridger, JM, Foster, Helen A., Abeydeera, Lalantha R., Bridger, Joanna M., Griffin, DK, Abeydeera, L, Griffin, Darren K.   +7 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Small supernumerary marker chromosomes (sSMC) in humans; are there B chromosomes hidden among them

Molecular Cytogenetics, 2008
Background Small supernumerary marker chromosomes (sSMC) and B-chromosomes represent a heterogeneous collection of chromosomes added to the typical karyotype, and which are both small in size.
Ogilvie Caroline, Kosyakova Nadezda, Mrasek Kristin, Liehr Thomas, Vermeesch Joris, Trifonov Vladimir, Rubtsov Nikolai   +6 more
doaj   +1 more source

Embryonic loss of human females with partial trisomy 19 identifies region critical for the single active X. [PDF]

PLoS ONE, 2017
To compensate for the sex difference in the number of X chromosomes, human females, like human males have only one active X. The other X chromosomes in cells of both sexes are silenced in utero by XIST, the Inactive X Specific Transcript gene, that is ...
Barbara R Migeon, Michael A Beer, Hans T Bjornsson   +2 more
doaj   +1 more source

Stretching the Rules: Monocentric Chromosomes with Multiple Centromere Domains [PDF]

, 2012
The centromere is a functional chromosome domain that is essential for faithful chromosome segregation during cell division and that can be reliably identified by the presence of the centromere-specific histone H3 variant CenH3.
Elizabeth Schroeder-Reiter, Schroeder-Reiter, Elizabeth, Chocholova, Eva, Neumann Pavel, Novák Petr, Petr Novák (2448673), Navrátilová Alice, Wanner, Gerhard, Macas Jiří, Gerhard Wanner (40161), Petr Novák, Koblížková Andrea, Jiří Macas (84231), Pavel Neumann, Steinbauerova, Veronika, Navratilova, Alice, Elizabeth Schroeder-Reiter (156901), Andrea Koblížková, Eva Chocholová (156910), Veronika Steinbauerová, Alice Navrátilová (84233), Macas, Jiri, Pavel Neumann (84232), Andrea Koblížková (156904), Neumann, Pavel, Koblizkova, Andrea, Eva Chocholová, Schroeder-Reiter Elizabeth, Wanner Gerhard, Jiří Macas, Veronika Steinbauerová (156907), Novak, Petr, Alice Navrátilová, Gerhard Wanner, Steinbauerová Veronika, Chocholová Eva   +35 more
core   +2 more sources