Results 21 to 30 of about 7,790,467 (300)

Natural selection reduced diversity on human y chromosomes. [PDF]

PLoS Genetics, 2014
The human Y chromosome exhibits surprisingly low levels of genetic diversity. This could result from neutral processes if the effective population size of males is reduced relative to females due to a higher variance in the number of offspring from males
Melissa A Wilson Sayres, Kirk E Lohmueller, Rasmus Nielsen   +2 more
doaj   +1 more source

Chromosomes distribute randomly to, but not within, human neutrophil nuclear lobes

iScience, 2021
Summary: The proximity pattern and radial distribution of chromosome territories within spherical nuclei are random and non-random, respectively. Whether this distribution pattern is conserved in the partitioned or lobed nuclei of polymorphonuclear cells
Christine R. Keenan, Michael J. Mlodzianoski, Hannah D. Coughlan, Naiara G. Bediaga, Gaetano Naselli, Erin C. Lucas, Qike Wang, Carolyn A. de Graaf, Douglas J. Hilton, Leonard C. Harrison, Gordon K. Smyth, Kelly L. Rogers, Thomas Boudier, Rhys S. Allan, Timothy M. Johanson   +14 more
doaj   +1 more source

Scanning conductance microscopy investigations on fixed human chromosomes

BioTechniques, 2008
Scanning conductance microscopy investigations were carried out in air on human chromosomes fixed on pre-fabricated SiO2 surfaces with a backgate. The point of the investigation was to estimate the dielectric constant of fixed human chromosomes in order ...
Casper Hyttel Clausen, Jacob Moresco Lange, Linda Boye Jensen, Pranjul Jaykumar Shah, Maria Ioannou Dimaki, Winnie Edith Svendsen   +5 more
doaj   +1 more source

Small supernumerary marker chromosomes derived from human chromosome 11

Frontiers in Genetics, 2023
Introduction: With only 39 reported cases in the literature, carriers of a small supernumerary marker chromosome (sSMC) derived from chromosome 11 represent an extremely rare cytogenomic condition.Methods: Herein, we present a review of reported sSMC(11),
Thomas Liehr, Monika Ziegler, Luisa Person, Stefanie Kankel, Niklas Padutsch, Anja Weise, Jörg Paul Weimer, Heather Williams, Susana Ferreira, Joana B. Melo, Isabel M. Carreira   +10 more
doaj   +1 more source

Staining and Embedding of Human Chromosomes for 3-D Serial Block-Face Scanning Electron Microscopy

BioTechniques, 2014
The high-order structure of human chromosomes is an important biological question that is still under investigation. Studies have been done on imaging human mitotic chromosomes using mostly 2-D microscopy methods.
Mohammed Yusuf, Bo Chen, Teruo Hashimoto, Ana Katrina Estandarte, George Thompson, Ian Robinson   +5 more
doaj   +1 more source

Viruses and their effect on human chromosomes

The Turkish Journal of Pediatrics, 1968
This investigation was performed in order to study the effect of nononcogenic viruses on human chromosomes. Measles, chickenpox and mumps cases were selected and peripheral leukocyte cultures were obtained for chromosomal analyses.
Yavuz Renda
doaj   +1 more source

Karyotyping human chromosomes by optical and X-ray ptychography methods [PDF]

, 2014
Sorting and identifying chromosomes, a process known as karyotyping, is widely used to detect changes in chromosome shapes and gene positions. In a karyotype the chromosomes are identified by their size and therefore this process can be performed by ...
Xiong, G, Harder, Ross, Robinson, Ian K., Robinson, IK, Shemilt, Laura, Yusuf, M, Shemilt, LA, Verbanis, E, Estandarte, AK, Zhang, F, Zhang, Fucai, Schwenke, J, Xiong, Gang, Yusuf, Mohammed, Parmar, Neha, Schwenke, Joerg, Parmar, N, Verbanis, Ephanielle, Estandarte, Ana K.   +18 more
core   +1 more source

Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes [PDF]

, 2005
Studies of higher-order chromatin arrangements are an essential part of ongoing attempts to explore changes in epigenome structure and their functional implications during development and cell differentiation.
Kreth Gregor, Michael R Speicher, Bolzer Andreas, Cremer Christoph, Kreth, G., Andreas Bolzer (83), Cremer, Christoph, Eils, R., Christoph Cremer, Christoph Cremer (91), Fauth Christine, Irina Solovei, Solovei, Irina, Daniela Koehler, Gregor Kreth (84), Eils, Roland, Gregor Kreth, Kaan Saracoglu, Bolzer, Andreas, Koehler Daniela, Irina Solovei (85), Fauth, C., Thomas Cremer (93), Bolzer, A., Speicher, Michael R., Müller Stefan, Solovei Irina, Müller, Stefan, Saracoglu, Kaan, Stefan Müller, Fauth, Christine, Roland Eils (90), Kreth, Gregor, Cremer Thomas, Koehler, D., Stefan Müller (89), Michael R Speicher (27551), Thomas Cremer, Solovei, I., Roland Eils, Müller, S., Cremer, C., Koehler, Daniela, Speicher, M.R., Eils Roland, Speicher Michael R, Cremer, Thomas, Andreas Bolzer, Daniela Koehler (86), Christine Fauth (88), Cremer, T., Saracoglu Kaan, Christine Fauth, Kaan Saracoglu (87), Saracoglu, K.   +54 more
core   +1 more source

Sorting of chromosomes by magnetic separation [PDF]

, 1988
Chromosomes were isolated from Chinese hamster x human hybrid cell lines containing four and nine human chromosomes. Human genomic DNA was biotinylated by nick translation and used to label the human chromosomes by in situ hybridization in suspension ...
Dudin, Gertrud, Steegmayer, Ernst W., Cremer, Thomas, E. Howell, Kathryn, Vogt, Peter, Schnitzer, Haide, Cremer, Christoph, Diaz, Eduardo   +7 more
core   +1 more source

Painting of human chromosomes with probes generated from hybrid cell lines by PCR with Alu and L1 primers [PDF]

, 1990
Specific amplification of human sequences of up to several kb length has recently been accomplished in man-hamster and man-mouse somatic hybrid cell DNA by IRS-PCR (interspersed repetitive sequence — polymerase chain reaction).
Riethman, Harold C., Cremer, Thomas, Lengauer, Christoph   +2 more
core   +1 more source