Results 111 to 120 of about 1,536,776 (399)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Análise do cariótipo de Apuleia leiocarpa (Vog.) Macbr. Analysis of Apuleia leiocarpa (Vog.) Macbr. karyotype

Ciência Rural, 1999
Estudos citogenéticos da Apuleia leiocarpa foram realizados com o objetivo de determinar e montar o cariótipo da espécie. As sementes utilizadas foram coletadas na localidade de Cerrito, município de Santa Maria - RS.
Neiva Maria Frizon Auler, Alice Battistin   +1 more
doaj   +1 more source

Comparative chromosome band mapping in primates byin situ suppression hybridization of band specific DNA microlibraries [PDF]

, 1991
A DNA-library established from microdissected bands 8q23 to 8q24.1 of normal human chromosomes 8 (Lüdecke et al., 1989) was used as a probe for chromosomal in situ suppression (CISS-) hybridization to metaphase chromosomes of man and primates including ...
A. Jauch, B. Dutrillaux, B. Horsthemke, C. Lengauer, C. Lengauer, D. Pinkel, D. Pinkel, H. J. Lüdecke, H.J. Lüdecke, J. Wienberg, J. Wienberg, J.J. Yunis, M. Klever, M. Small, P. Lichter, P.A. Lalley, R. Stanyon, R. Stanyon, R. Stanyon, S.J. O'Brien, T. Cremer   +20 more
core   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source

The role of EGFR double minutes in modulating the response of malignant gliomas to radiotherapy. [PDF]

, 2017
EGFR amplification in cells having double minute chromosomes (DM) is commonly found in glioblastoma multiforme (GBM); however, how much it contributes to the current failure to treat GBM successfully is unknown.
Atkin, Naomi, Chen, Yumay, Gau, Alex, Giedzinski, Erich, Hu, Yuanjie, Lee, Nathan, Limoli, Charles, Linskey, Mark E, Ly, Khang Chi, Pan, Francine, Qiao, Jiao, Ru, Ning, Siegel, Eric R, Tran, Katherine, Wang, Ping, Yu, Liping, Zhou, Yi-Hong   +16 more
core   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

(Ovo-)viviparity in the darkling beetle, Alegoria castelnaui (Tenebrioninae: Ulomini), from Guadeloupe

European Journal of Entomology, 2010
In the course of cytogenetic studies on Alegoria castelnaui Fleutiaux & Sallé 1889 (Coleoptera: Tenebrionidae: Tenebrioninae: Ulomini) from Guadeloupe, a number of adult specimens were dissected.
Anne Marie DUTRILLAUX, Dominique PLUOT-SIGWALT, Bernard DUTRILLAUX   +2 more
doaj   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Chromosome Level Genome Assembly and Comparative Genomics between Three Falcon Species Reveals an Unusual Pattern of Genome Organisation

Diversity, 2018
Whole genome assemblies are crucial for understanding a wide range of aspects of falcon biology, including morphology, ecology, and physiology, and are thus essential for their care and conservation.
Sunitha Joseph, Rebecca E. O’Connor, Abdullah F. Al Mutery, Mick Watson, Denis M. Larkin, Darren K. Griffin   +5 more
doaj   +1 more source

Condensins: universal organizers of chromosomes with diverse functions.

Genes & Development, 2012
Condensins are multisubunit protein complexes that play a fundamental role in the structural and functional organization of chromosomes in the three domains of life.
T. Hirano
semanticscholar   +1 more source