Results 331 to 340 of about 1,562,582 (397)

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes

Nature, 2016
Eukaryotic genomes are partitioned into chromosomes that form compact and spatially well-separated mechanical bodies during mitosis. This enables chromosomes to move independently of each other for segregation of precisely one copy of the genome to each ...
Antonio Z Politi, Thomas Müller-Reichert, Ina Poser   +2 more
exaly   +2 more sources

Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium

Nature, 2010
Fusarium species are among the most important phytopathogenic and toxigenic fungi. To understand the molecular underpinnings of pathogenicity in the genus Fusarium, we compared the genomes of three phenotypically diverse species: Fusarium graminearum ...
Jeffrey J Coleman, Antonio Di Pietro, Michael Freitag   +2 more
exaly   +2 more sources

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SMC complexes: from DNA to chromosomes

Nature Reviews Molecular Cell Biology, 2016
Frank Uhlmann
exaly   +2 more sources

Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators

Nature, 2014
The human X and Y chromosomes evolved from an ordinary pair of autosomes, but millions of years ago genetic decay ravaged the Y chromosome, and only three per cent of its ancestral genes survived. We reconstructed the evolution of the Y chromosome across
Daniel W Bellott, Jennifer F Hughes, Helen Skaletsky   +2 more
exaly   +2 more sources

DNA methylation profiling of human chromosomes 6, 20 and 22

Nature Genetics, 2006
DNA methylation is the most stable type of epigenetic modification modulating the transcriptional plasticity of mammalian genomes. Using bisulfite DNA sequencing, we report high-resolution methylation profiles of human chromosomes 6, 20 and 22, providing
Rene Cortese, Kevin L Howe, Stephan Beck
exaly   +2 more sources

Origins and functional evolution of Y chromosomes across mammals

Nature, 2014
Diego Cortez, Ray M Marin, Paul D Waters
exaly   +2 more sources

Telomeres: protecting chromosomes against genome instability

Nature Reviews Molecular Cell Biology, 2010
Jan Karlseder
exaly   +2 more sources

Chromosomics

Cytogenetic and Genome Research, 2005
The term “chromosomics” is introduced to draw attention to the three-dimensional morphological changes in chromosomes that are essential elements in gene regulation. Chromosomics deals with the plasticity of chromosomes in relation to the three-dimensional positions of genes, which affect cell function in a developmental and tissue-specific manner ...
openaire   +2 more sources

Lampbrush chromosomes

Journal of Cell Science, 1977
ABSTRACT 1986 was a celebration year for lampbrush chromosomes (LBCs), marked by the publication of Callan’s comprehensive and authoritative book on these structures. My commentary begins where Callan’s book ends, standing on tiptoe beside a large and rather neat assembly of well-established facts, principles and hypotheses, and trying ...
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Chromosome imprinting and the mammalian X chromosome

Nature, 1975
Chromosome imprinting is the process by which one of two genetically homologous chromosomes is predetermined to function differently from the other at a subsequent stage in development. In the coccid insects, imprinting occurs in the egg, at the time of fertilisation; it probably occurs at the same time and site in mammals, and possibly also in Sciara.
H S, Chandra, S W, Brown
openaire   +2 more sources