Results 61 to 70 of about 1,530,143 (402)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Combined method for simultaneous morphology, immunophenotype and karyotype (MAC) in leukemias

São Paulo Medical Journal
In the present study, a combined method (CM) for attaining simultaneous identification of leukemic cell morphology, karyotype and immunophenotype has been evaluated in 21 patients with acute leukemia and 1 with CML in blast crisis were studied for ...
Maria de Lourdes Lopes Ferrari Chauffaille, Vicente Coutinho, Mihoko Yamamoto, José Kerbauy   +3 more
doaj   +1 more source

Chromosomics: Bridging the Gap between Genomes and Chromosomes [PDF]

Genes, 2019
The recent advances in DNA sequencing technology are enabling a rapid increase in the number of genomes being sequenced. However, many fundamental questions in genome biology remain unanswered, because sequence data alone is unable to provide insight into how the genome is organised into chromosomes, the position and interaction of those chromosomes in
Ikuo Miura, Lukáš Kratochvíl, Kichi Fukui, Janine E. Deakin, Mark D. B. Eldridge, Tariq Ezaz, Darren K. Griffin, Kornsorn Srikulnath, Marcelo de Bello Cioffi, Michail Rovatsos, Erik Wapstra, Aurora Ruiz-Herrera, Sally Potter, Sally Potter, Frank Grützner, Rachel J. O’Neill, Jennifer A. Marshall Graves, Jennifer A. Marshall Graves   +17 more
openaire   +7 more sources

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

FEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel, A. F. Volker Wagner, R. Gary Sawers   +2 more
wiley   +1 more source

Single strand conformation polymorphism (SSCP) detection in six genes in Portuguese indigenous sheep breed [PDF]

Biotechnologie, Agronomie, Société et Environnement, 2001
Evaluation of the genetic diversity for six genes in forty animals of the Portuguese indigenous sheep breed (Ovis aries) ""Churra da Terra Quente"" was done.
Guedes-Pinto H., Bastos E., Cravador A., Azevedo J.   +3 more
doaj  

Bioengineering and Molecular Biology of Miscanthus

Energies, 2022
Miscanthus is a perennial wild plant that is vital for the production of paper and roofing, as well as horticulture and the development of new high-yielding crops in temperate climates.
Evgeny Chupakhin, Olga Babich, Stanislav Sukhikh, Svetlana Ivanova, Ekaterina Budenkova, Olga Kalashnikova, Alexander Prosekov, Olga Kriger, Vyacheslav Dolganyuk   +8 more
doaj   +1 more source

\u3cem\u3eAnolis\u3c/em\u3e Sex Chromosomes Are Derived from A Single Ancestral Pair [PDF]

, 2014
To explain the frequency and distribution of heteromorphic sex chromosomes in the lizard genus Anolis, we compared the relative roles of sex chromosome conservation versus turnover of sex‐determining mechanisms. We used model‐based comparative methods to
Gamble, Tony, Geneva, Anthony J., Glor, Richard E., Zarkower, David   +3 more
core   +1 more source

High resolution physical mapping of single gene fragments on pachytene chromosome 4 and 7 of Rosa [PDF]

, 2015
Background: Rosaceae is a family containing many economically important fruit and ornamental species. Although fluorescence in situ hybridization (FISH)-based physical mapping of plant genomes is a valuable tool for map-based cloning, comparative ...
Khrustaleva, Ludmila I, Kirov, Ilya V, Van Laere, Katrijn   +2 more
core   +2 more sources

Chromatin and chromosomes

Molecular Biology of the Cell, 2011
Recent advances in our understanding of chromosome behavior have been made possible by the development of cutting-edge cytological and molecular techniques. Presentations in this Minisymposium applied these techniques to a diverse set of topics. Sarah Elgin (Washington University) described her lab’s studies on the 1360 transposable element in ...
Lori L. Wallrath, David M. Gilbert
openaire   +3 more sources

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source