Results 231 to 240 of about 7,658,149 (357)

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

FEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li, XianShuai Xu, GuangZheng Liu, XiaoQian Lv, JiuZhou Song, HongYan Sun, YingJie Niu, QiSheng Zuo, Wei Han, BiChun Li, Kai Jin   +10 more
wiley   +1 more source

Prevalence and patterns of multimorbidity among adults in rural Shanxi Province, China: A post-hoc exploratory subgroup analysis of a cross-sectional study. [PDF]

PLoS One
Tang S, Li Y, Li R, Yang H, Hao T, Tian M, Zhang X, Feng X, Li Z.   +8 more
europepmc   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

The current situation and factors influencing the use of traditional Chinese medicine therapies among patients with chronic disease in china: a cross-sectional study. [PDF]

Sci Rep
Cao Y, Huang T, Deng H, Zhang J, Guo F, Yin W, Hu J, Chen Z, Guo H.   +8 more
europepmc   +1 more source

Structural and functional analysis of Bacillus sarcosine oxidase and its activity toward cyclic imino acids

FEBS Open Bio, EarlyView.
Sarcosine oxidase from Bacillus sp. (SoxB) recognizes l‐proline (l‐Pro), d‐proline (d‐Pro), and l‐thioproline (l‐Tpr) as minor substrates. In this study, we measured their absorption spectra, determined the crystal structures of their enzyme complexes, and performed site‐directed mutagenesis of key residues.
Yuqi Zhang, Yoshitaka Nakajima, Masae Kurobe, Tsutomu Nakamura, Tomoki Himiyama, Yoshiaki Nishiya   +5 more
wiley   +1 more source

Understanding economic disparities in elderly health outcomes: a decomposition analysis in Bankura district. [PDF]

BMC Public Health
Das U, Kar N.
europepmc   +1 more source

THE EFFECT OF ORGANIC DIETARY CONSTITUENTS UPON CHRONIC FLUORINE TOXICOSIS IN THE RAT

, 1935
Paul H. Phillips, E.B. Hart
openalex   +1 more source

Designing and Delivering Effective Faculty Development With the Adult Learner in Mind

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT University faculty are busy professionals tasked with many different responsibilities. While they certainly care about student success, their expertise is generally discipline‐specific and strategies for effective and engaging teaching are developed in the classroom along the way.
Nancy V. Winfrey
wiley   +1 more source

Social Connection and Chronic Pain: A Cohort Study to Explore the Association of Social Isolation and Loneliness with Chronic Pain Among Older Adults in China. [PDF]

J Pain Res
Han X, Qiao Y, Tan J, Luo Z, Nicholas S, Maitland E, Han L, Xu Z, Wang J.   +8 more
europepmc   +1 more source

Instructional Design and Facilitation for Multigenerational Online Learning in Higher Education—Baby Boomers, Generation X, Millennials, and Generation Z

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Nontraditional students represent a substantial number and significant percentage of students in higher education. While these adult learners have similarities, they also span 50+ years with generational differences. At the same time, online learning is on the rise, offering opportunities and challenges for nontraditional students and those ...
Brittany Hyden, Catherine A. Cherrstrom
wiley   +1 more source