Results 231 to 240 of about 4,397,402 (317)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Association of life's essential 8 with chronic respiratory disease mortality and lung health: a national cohort study. [PDF]

BMJ Open Respir Res
Wu Y, Feng Y, Dai Z, Li J, Zhu M, Chen H, Cao C, Xiong K.   +7 more
europepmc   +1 more source

Chronic treatment with glucocorticoids alters rat hippocampal and prefrontal cortical morphology in parallel with endogenous agmatine and arginine decarboxylase levels

, 2007
Meng‐Yang Zhu, Weiping Wang, Jingjing Huang, S. Regunathan   +3 more
openalex   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Critical appraisal and comparison of clinical practice guideline recommendations for the treatment of anaemia in chronic kidney disease: a systematic review protocol. [PDF]

BMJ Open
Agnelli JCM, Costa WRD, Iwami RS, Franques RT, Lopes LC, Barberato-Filho S, Bergamaschi CC.   +6 more
europepmc   +1 more source

Survival of macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking in patients with type 2 diabetes: BioBank Japan cohort

, 2017
Hiroshi Yokomichi, Akiko Nagai, Makoto Hirata, Yutaka Kiyohara, Kaori Muto, Toshiharu Ninomiya, Koichi Matsuda, Yoichiro Kamatani, Akiko Tamakoshi, Michiaki Kubo, Yusuke Nakamura, Zentaro Yamagata, Hiromasa Harada, Sunao Matsubayashi, Rieko Komi, Kazuo Misumi, Shiro Minami, Hitoshi Sugihara, Eitaro Kodani, Akio Kanazawa, Hiromasa Gotoh, Hidenori Haruna, Satoshi Asai, Mitsuhiko Moriyama, Yasuo Takahashi, Tomoaki Fujioka, Wataru Obara, Seijiro Mori, Hideki Ito, Satoshi Nagayama, Yoshio Miki, Akihide Masumoto, Akira Yamada, Yasuko Nishizawa, Ken Kodama, Satoshi Ugi, Shin‐ichi Araki, Yukihiro Koretsune, Hideki Taki, Takayuki Nakagawa   +39 more
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

How do chronic diseases affect personal and household income? A double debiased machine learning analysis of the China health and retirement longitudinal study (CHARLS) in older adults. [PDF]

BMJ Open
Zhi T, Chen C, Shang W, Li Q, Zhang S, Wang Q.   +5 more
europepmc   +1 more source

Chronic fatigue

Western Journal of Medicine, 2001
openaire   +3 more sources

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source