Results 31 to 40 of about 114,973 (254)

Mnestic functions restoration due to chronic brain ischemia pathogenetically oriented pharmacocorrection as a condition to enhance cerebral resistance

open access: yesJournal of Education, Health and Sport
The purpose of the study was to investigate the efficacy of separate and combined administration of pentoxifylline, memantine and xavron in the pharmacological correction of cognitive impairment in rats under conditions of experimental chronic brain ...
O. Myronov
doaj   +1 more source

Estimation of thiocetam influence on glutathione link of thiol disulfide cerebral system in conditions of experimental chronic ischemia

open access: yesPatologìâ, 2015
Aim. Pharmacological remodeling of pathologic changes when cerebral ischemia takes place is actual task for today. With the purpose of thiocetam neuroprotective properties studying in conditions of experimental chronic cerebral ischemia the ...
A. V. Demchenko, І. F. Belenichev
doaj   +1 more source

A multimodal approach in the treatment of chronic cerebral ischemia: what should a doctor know?

open access: yesМедицинский совет, 2020
The article discusses one of the leading problems of modern angioneurology - chronic cerebral ischemia. The main etiological factors playing a significant role in the development of chronic cerebral ischemia, among which atherosclerosis, hypertension ...
N. V. Pizova
doaj   +1 more source

Glutamate biomarkers in comprehensive diagnostics of acute and chronic brain ischemia

open access: yesАнналы клинической и экспериментальной неврологии, 2020
The development and implementation of biomarkers of ischaemic brain damage at the pre-hospital and hospital stages, as well as during screening and regular medical examinations, are a priority in neurology.
Grigory V. Ponomarev   +3 more
doaj   +1 more source

Prevalence and severity of depression in patients with the consequences of ischemic strokes and in patients with chronic brain ischemia

open access: yesJournal of Education, Health and Sport, 2021
The aim of our study was to investigate the prevalence and severity of depression in patients with the consequences of ischemic strokes and in patients with chronic brain ischemia. Material and Methods.
A. Babirad
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Experience with Transcranial Electrical Stimulation in the Assessment of the Microvascular Bed by Contrast-Free Magnetic Resonance Perfusion Imaging in Patients with Chronic Cerebral Ischemia

open access: yesВестник рентгенологии и радиологии, 2022
Objective: to define the role of transcranial electrical stimulation in the assessment of the microvascular bed by contrast-free magnetic resonance (MR) perfusion imaging in patients with chronic cerebral ischemia. Material and methods. Examinations were
Е. S. Chukhontseva   +2 more
doaj   +1 more source

Comorbidity profile in chronic brain ischemia on the background of multifocal atherosclerosis.

open access: yesMedicni perspektivi (Medical perspectives), 2019
Aim to evaluate the comorbidity profile in patients with chronic cerebral ischemia on the background of multifocal atherosclerosis. The study included 137 patients aged 40 to 84 years with chronic cerebral ischemia (CСI) on the background of multifocal atherosclerosis, which were divided into three clinical groups depending on the localization of ...
Dzyak L.А., Rosytska О.А.
openaire   +4 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

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