Results 181 to 190 of about 2,897,650 (254)

Multi‐Target Pharmacological Mechanisms of Salvia miltiorrhiza Bunge in Metabolic Syndrome and Cardiovascular Diseases: A Comprehensive Review Based on the Theory of “Same Treatment for Different Diseases”

Phytotherapy Research, EarlyView.
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia, Kaiyi Wu, Jiaying Qi, Nana Huang, Yusheng Liu, Xiumei Gao, Rong Sun   +6 more
wiley   +1 more source

Prostaglandin E2 in Brain Inflammation: Roles and Dynamics. [PDF]

Brain Sci
Nakanishi T, Fukuchi M.
europepmc   +1 more source

Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases

Phytotherapy Research, EarlyView.
Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin, Inho Cho, Xue Zhu, Ke Wang, Ling Zhu, Wenchang Wong, Michael Murray, Fanfan Zhou   +7 more
wiley   +1 more source

Salidroside Alleviates AlCl3/D‐galactose‐Induced Alzheimer's Disease‐Like Mice Neuronal Damage and Synaptic Dysfunction Through Keap1/Nrf2/GSH Signaling Axis

Phytotherapy Research, EarlyView.
Salidroside alleviates AlCl3/D‐galactose‐induced neuronal injury and synaptic dysfunction in AD‐like mice via regulation of the Keap1/Nrf2/GSH signaling axis. ABSTRACT Alzheimer's disease (AD) is associated with glutathione (GSH) depletion and redox imbalance in the brain, contributing to hippocampal neuronal damage and synaptic dysfunction and ...
Heying Cui, Yihua Han, Yanzhu Lu, Shuhua Zheng, Ruijing Zhang, Xianjing Zhang, Zheng Nan, Xiangdan Li, Songbiao Cui, Dongyuan Xu   +9 more
wiley   +1 more source

PVT inhibition mitigates neuropathology and cognitive deficits in chronic cerebral hypoperfusion. [PDF]

iScience
Guan Y, Ma J, Li R, Xu J, Xu T, Li G, Sun L.   +6 more
europepmc   +1 more source

Toll‐Like Receptor 4 Signaling in Natural N‐Acylethanolamines and Derivative NAE‐Like Compounds: Mechanisms and Implications for Neuroimmune and Inflammatory Processes in a Systematic Search Approach

Phytotherapy Research, EarlyView.
ABSTRACT N‐acylethanolamines (NAEs) are endogenous fatty acid amides structurally related to the endocannabinoid anandamide and function as bioactive lipid mediators with broad regulatory roles in inflammation and neuroinflammation. Among pattern‐recognition receptors, Toll‐like receptor 4 (TLR4) occupies a central position in innate immune ...
Damiana Scuteri, Francesca Guida, Giacinto Bagetta, Sabatino Maione, Maria Tiziana Corasaniti, Morena Zusso   +5 more
wiley   +1 more source

Icariside II in Neurological Disorders: Mechanistic Insights Into Alzheimer's Disease, Cerebral Ischemia and Parkinson's Disease. [PDF]

J Biochem Mol Toxicol
Solanki A, Sharma K, Jain J, Singh NK, Krishnamurthy PT.   +4 more
europepmc   +1 more source

New approaches to neuroprotection in chronic cerebral hypoperfusion in the rat [PDF]

, 2008
Institóris Ádám
core  

The Effect of Natural Compounds on Cognitive Impairment Through BDNF/TrkB/CREB Pathway: A Review

Phytotherapy Research, EarlyView.
Natural compounds improve cognitive function by activating BDNF/TrkB/CREB signaling to reduce neuroinflammation, oxidative stress, apoptosis, and Aβ accumulation while promoting synaptogenesis. ABSTRACT Considering the global prevalence of Alzheimer's disease (AD) and the restrictions of current treatment procedures, natural compounds (such as curcumin,
Vahid Pourbarkhordar, Sohrab Rahmani, Hossein Hosseinzadeh, Soghra Mehri   +3 more
wiley   +1 more source

Precision Oxygen Modulation in the Reperfusion Era: Conditioning and Therapeutic Strategies in Ischemic Stroke. [PDF]

J Stroke
Liu W, Li Z, Sun Z, Liu J, Ji X.
europepmc   +1 more source