UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Emergency Department Utilization Patterns and Regional Disparities in Access to Care for Children With Complex Chronic Conditions in Korea: A Nationwide Analysis. [PDF]
Choi YY +4 more
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Managing vulnerability: cross-sector reflections on the ethics and equity implications of AI use among young adults with chronic conditions. [PDF]
Isaac M, Dave S, Adirim T.
europepmc +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Chronic Conditions and Mortality in Medicare Beneficiaries Before and After the COVID-19 Pandemic.
Waken RJ +7 more
europepmc +1 more source
Self-care in children and young people with complex chronic conditions instrument: development and content validation. [PDF]
Manzi G +15 more
europepmc +1 more source
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Chronic conditions and adolescents' psychosocial wellbeing: the impact of self-reporting. [PDF]
Berkelbach van der Sprenkel EE +7 more
europepmc +1 more source

