Results 91 to 100 of about 2,833,592 (329)
Biotechnology and Bioengineering, EarlyView.The probiotic E. coli Nissle 1917 was engineered to enable stable and antibiotic free protein expression platforms using native plasmids. Further modification aids in the production of high‐level protein expression for antimicrobial secretion whose activity is comparable to industry standard E. coli BL21.
Halimatun Sakdiah Zainuddin +2 more
wiley +1 more source
Clinical Pharmacology in Drug Development, EarlyView.Abstract Asciminib is the first BCR::ABL1 inhibitor that Specifically Targets the ABL Myristoyl Pocket (STAMP) in patients with chronic myeloid leukemia. This phase 1, two‐treatment‐period, drug‐drug interaction study evaluated the effect of steady‐state asciminib on the pharmacokinetics of atorvastatin.
Matthias Hoch +9 more
wiley +1 more source
Current developments in pharmacological therapeutics for chronic constipation
Acta Pharmaceutica Sinica B, 2015 Chronic constipation is a common gastrointestinal disease severely affecting the patient׳s quality of life. The traditional treatment of constipation is the use of laxatives.
Chunhuan Jiang +3 more
doaj +1 more source
Epileptic Disorders, EarlyView.Abstract Objective To summarize the electro‐clinical and genetic characteristics of children with Mowat–Wilson syndrome (MWS). Methods This study is a hospital‐based case series analyzing clinical data from 31 pediatric patients with MWS and epilepsy treated at Peking University First Hospital between June 2020 and December 2024.
Yi Ju, Tao‐yun Ji
wiley +1 more source
Weaning from ketogenic diet therapy in children with epilepsy: Insights from a retrospective study
Epilepsia, EarlyView.Abstract Objective This study was undertaken to describe weaning practices following ketogenic diet therapy (KDT) in children with epilepsy and to identify clinical factors associated with seizure exacerbation or antiseizure medication adjustments during or after weaning from KDT.
Noémie Donnard +10 more
wiley +1 more source
Epilepsia Open, EarlyView.Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza +4 more
wiley +1 more source
Epidemiology and Burden of Chronic Constipation
Canadian Journal of Gastroenterology, 2011 Chronic constipation is an important component of clinical gastroenterology practice worldwide. Based on the definition, either self-reported or using Rome criteria, chronic constipation can affect from 2% to 27% of the population.
Maria Ines Pinto Sanchez, Premysl Bercik
doaj +1 more source
Noise, Vibration, and Harshness (NVH) Challenges in Hydrogen Internal Combustion Engine Vehicles
Energy Science &Engineering, EarlyView.ABSTRACT This paper presents a state‐of‐the‐art literature review on noise, vibration, and harshness (NVH) in hydrogen‐fuelled internal combustion engines. Studies published between 2011 and 2025 were screened, covering fundamental flame physics, test‐bench work, and recent prototype vehicles.
Krisztián Horváth
wiley +1 more source
Functional Chronic Constipation: Rome III Criteria Versus Rome IV Criteria
Journal of Neurogastroenterology and Motility, 2019 Background/Aims Functional constipation (FC) is aa frequent functional gastrointestinal disorder, diagnosed according to the Rome criteria. In this study, we compared Rome III and Rome IV criteria for the diagnosis of FC, and determined the prevalence of
M. Russo +5 more
semanticscholar +1 more source