Results 81 to 90 of about 100,430 (293)

Economic burden associated with chronic constipation in Sweden: a retrospective cohort study

open access: yesClinicoEconomics and Outcomes Research, 2014
Sara Bruce Wirta,1 Paul Hodgkins,2 Alain Joseph3 1IMS Health, Stockholm, Sweden; 2Shire, Wayne, PA, USA; 3Shire, Eysins, Switzerland Background: Chronic constipation is a common condition, but few studies have assessed its cost and impact on resource ...
Bruce Wirta S, Hodgkins P, Joseph A
doaj  

Prenatal Evaluation of RNU4‐2 Variants in Fetuses With Central Nervous System Anomalies

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Fetal central nervous system (CNS) anomalies are among the most common congenital malformations, yet the overall prenatal diagnostic yield of current genetic testing remains below 40%. Variants in RNU4‐2, a non‐coding gene encoding the U4 small nuclear RNA (snRNA), have recently been linked to a novel highly recurrent dominant ...
Yiyao Chen   +13 more
wiley   +1 more source

Constipation in CKD

open access: yesKidney International Reports, 2020
Constipation is one of the most common gastrointestinal disorders among patients with chronic kidney disease (CKD) partly because of their sedentary lifestyle, low fiber and fluid intake, concomitant medications (e.g., phosphate binders), and multiple ...
Keiichi Sumida   +2 more
doaj   +1 more source

Epidemiology and management of chronic constipation in elderly patients

open access: yes, 2015
Maria Vazquez Roque, Ernest P Bouras Gastroenterology and Hepatology Department, Mayo Clinic, Jacksonville, FL, USA Abstract: Constipation is a common functional gastrointestinal disorder, with prevalence in the general population of approximately 20%.
Vazquez Roque M, Bouras EP
core  

Shotgun Metagenomic Profiling of the Gut Virome in Prodromal and Confirmed Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
We conducted a nested case‐control study within the Nurses’ Health Study and the Health Professionals Follow‐up Study to examine the role of the gut virome (GV) in Parkinson's disease (PD). We applied a novel metagenomic virome profiling approach, Bioinformatic Application for Quantification and Labeling of Viral taxonomy (BAQLaVa), to prospectively ...
Deepika Dinesh   +7 more
wiley   +1 more source

Studies of pathophysiology and psychosocial functioning in adolescents with anorectal anomalies

open access: yes, 2011
PhDIntroduction: Anorectal anomalies (ARA) are a range of congenital conditions ranging from a slight malposition of the anus to complex anomalies of the hindgut and urogenital organ.
Athanasakos, Eleni P
core  

Anorectal Manometry Results of Patients Presenting with Chronic Constipation: Single-Center Outcomes

open access: yes
Objective: Anorectal manometry serves as a diagnostic tool, particularly in identifying chronic constipation associated with rectal evacuation disorders.
Venüs Tekoğlu   +3 more
core   +1 more source

Gephyrin Neurological Autoimmunity

open access: yesAnnals of Neurology, EarlyView.
Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano   +10 more
wiley   +1 more source

Synergistic Advanced Oxidation and Physicochemical Treatment Strategies for Antibiotic Removal and Resistance Mitigation in Water

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The presence of antibiotics in water not only causes environmental pollution but also increases the growth of antibiotic‐resistant bacterial genes, which pose serious threats to human beings and other water residents. Large numbers of people are reportedly affected by the resistant bacterial genes, as many broad‐spectrum antibiotics are not ...
Amir Zada, Shohreh Azizi
wiley   +1 more source

Approaches to managing chronic constipation

open access: yes, 2016
Constipation is a common presenting problem, but its treatment is often unsatisfactory. It is important for nurses to remember that constipation is a symptom and not a disease.
Bardsley, Alison
core   +1 more source

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