Results 171 to 180 of about 84,272 (327)

Immune response features in children with chronic constipation

Кубанский научный медицинский вестник, 2016
In the article the results of examination of some immune characteristics, including some autoantibodies in 28 children with chronic constipation are represented. Increased levels of circulating immune complexes and increased spontaneous NST test were the
O. V. Moskalets, V. I. Scherbina
doaj  

Chronic constipation: focus on microbiome-targeted therapies with prebiotics, probiotics, and synbiotics

Alʹmanah Kliničeskoj Mediciny
Chronic constipation is a global medical, social, and economic problem due to its negative impact on patients’ quality of life and increased risk of colorectal cancer, cardiovascular and cerebrovascular disorders. The gut microbiota plays an important
Margarita Y. Serkova, Elena B. Avalueva, Stanislav I. Sitkin   +2 more
doaj   +1 more source

Evidence for motor neuropathy and reduced filling of the rectum in chronic intractable constipation. [PDF]

, 1990
David Waldron, Dinesh Kumar, R I Hallan, D. L. Wingate, N S Williams   +4 more
openalex   +1 more source

Pharmacokinetics and Safety of Fenofibrate in Participants with Mild Hepatic Impairment or with Advanced Fibrosis due to Metabolic‐Associated Fatty Liver Disease

The Journal of Clinical Pharmacology, EarlyView.
Abstract Fenofibrate is contraindicated in patients with advanced hepatic fibrosis due to limited clinical data. We evaluated the pharmacokinetics and safety of fenofibrate in participants with mild hepatic impairment (phase 1 study) or advanced fibrosis due to metabolic‐associated fatty liver disease (MAFLD; phase 2a study).
Islam R. Younis, Elijah J. Weber, Cara Nelson, Ann R. Qin, Timothy R. Watkins, Ahmed A. Othman   +5 more
wiley   +1 more source

INFORMATIVE ENERGY EXCHANGE OF PERIPHERAL LYMPHOCYTE BLOOD MITOCHONDRIA IN CHILDREN WITH CHRONIC CONSTIPATION

Вопросы современной педиатрии, 2007
The article discusses the study of cell metabolism condition in chronic constipation children based on the activities of the two mitochondrion enzymes, succinate dehydrogenate and glycerophosphate dehydrogenase detected in cytochemical analysis of blood ...
G.F. Semenova, E.V. Komarova, A.S. Potapov, A.V. Petrova, V.M. Shishchenko, S.V. Petrichuk   +5 more
doaj   +2 more sources

Randomized controlled trial protocol to analyze the effects of rice with different contents of resistant starch on chronic constipation

Scientific Reports
The trend of the aging population worldwide is becoming increasingly severe. As people age, constipation becomes increasingly common in older adults, causing varying degrees of physical and psychological harm to them.
Yiping Zhao, Fanyu Zhao, Qian Liu, Li Liu, Fang Wang, Xiuying Hu   +5 more
doaj   +1 more source

Constipation in CKD

Kidney International Reports, 2020
Constipation is one of the most common gastrointestinal disorders among patients with chronic kidney disease (CKD) partly because of their sedentary lifestyle, low fiber and fluid intake, concomitant medications (e.g., phosphate binders), and multiple ...
Keiichi Sumida, Kunihiro Yamagata, Csaba P. Kovesdy   +2 more
doaj  

In Vitro and Clinical Evaluations of UGT1A1‐, P‐gp‐, OATP1B1‐, and BCRP‐Mediated Drug–Drug Interactions of Belumosudil, a Potent ROCK2 Inhibitor

The Journal of Clinical Pharmacology, EarlyView.
Abstract Belumosudil is an oral selective rho‐associated coiled‐coil containing protein kinase 2 inhibitor, approved as a treatment for chronic graft‐versus‐host disease. Prior clinical studies demonstrated that coadministration with strong CYP3A4 inducers or proton pump inhibitors requires dose modification of belumosudil.
Olivier Schueller, Lauren Lohmer, Felix Beck, Jeegar Patel, Jasminder Sahi   +4 more
wiley   +1 more source

MODERN VIEWS ON A PROBLEM OF CONSTIPATION IN CHILDREN — A POSITION OF PEDIATRICIANS

Педиатрическая фармакология, 2009
This article highlights the issues of definition and classification of chronic constipation, the most prevailing pathology among gastrointestinal tract diseases.
F.Ch. Shakhtakhtinskaya
doaj   +2 more sources

Evaluation of the efficacy of prucalopride (resolor) in the treatment of patients with chronic constipation

Терапевтический архив, 2013
AIM: To evaluate the efficacy of the enterokinetic prucalopride (resolor) in patients with chronic constipation. Subjects. The effect of treatment with prucalopride (resolor) in 109 patients with chronic constipation was analyzed/RESULTS: The effect was ...
M F Osipenko, E A Bikbulatova, M A Skalinskaia, Iu A Kulygina, L Iu Pankova   +4 more
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