Protocol for a randomised control trial of methylnaltrexone for the treatment of opioid-induced constipation and gastrointestinal stasis in intensive care patients (MOTION) [PDF]
Gastrointestinal dysmotility and constipation are common problems in intensive care patients. The majority of critical care patients are sedated with opioids to facilitate tolerance of endotracheal tubes and mechanical ventilation, which inhibit ...
Anjum, Aisha+6 more
core +2 more sources
Constipation and encopresis in children [PDF]
Chronic constipation is defined as a decrease in frequency or the painful passage of bowel movements present for several weeks. Retentive encopresis is the term reserved for the involuntary and uncontrollable soiling that occurs in children with chronic ...
Aquilina, Samuel, Attard, Thomas
core
Response to a behavioural treatment, biofeedback, in constipated patients is associated with improved gut transit and autonomic innervation [PDF]
Background: Although behavioural treatment (biofeedback) successfully treats the pelvic floor abnormalities in patients with idiopathic constipation, many patients also normalise their impaired bowel frequency.
Emmanuel, A.V., Kamm, M.A.
core +2 more sources
Management of chronic constipation in comorbid conditions [PDF]
Constipation is a common clinical problem in India. It is also a secondary condition in many disorders. This article focused on clinical assessment and evidence-based treatment options for managing chronic constipation in various disorders.
Bagepally, Ravi Shankar
core +2 more sources
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Chronic Constipation: Current Treatment Options
Chronic constipation is a common functional gastrointestinal disorder that affects patients of all ages. In 2007, a consensus group of 10 Canadian gastroenterologists developed a set of recommendations pertaining to the management of chronic constipation
Louis Wing Cheong Liu
doaj +1 more source
Ultrastructural analysis of changes in neurons of the mouse internal anal sphincter during ageing [PDF]
Gastrointestinal disorders, including chronic constipation, faecal impaction and incontinence, are a major cause of morbidity in the ...
Colyer, Frances+5 more
core
Gigantic Stomach: A Rare Manifestation of Duchenne Muscular Dystrophy [PDF]
Duchenne muscular dystrophy (DMD) is characterized by degeneration and atrophy of skeletal, cardiac, and smooth muscles after a latent period of apparently normal development and function. The gastrointestinal manifestations start in the second decade of
Dhaliwal, Amaninder+4 more
core +2 more sources
Shared features of endothelial dysfunction between sepsis and its preceding risk factors (aging and chronic disease) [PDF]
Acute vascular endothelial dysfunction is a central event in the pathogenesis of sepsis,increasing vascular permeability, promoting activation of the coagulation cascade, tissue edema and compromising perfusion of vital organs. Aging and chronic diseases(hypertension,dyslipidaemia,diabetes mellitus,chronic kidney disease,cardiovascular disease ...
arxiv +1 more source
AUTOINTOXICATION IN CHRONIC CONSTIPATION [PDF]
The group of symptoms generally recognized as attributable to intestinal toxemia is too well known to require recapitulation. A priori , the most striking fact that presents itself is the great similarity between the symptoms referable to focal infection and those of intestinal toxemia.
openaire +3 more sources