Results 61 to 70 of about 2,833,592 (329)

Chronic Constipation: Current Management and Challenges

Canadian Journal of Gastroenterology, 2011
Many challenges are associated with the diagnosis and management of patients with chronic constipation. Some of these challenges arise from the currently incomplete understanding of what causes constipation and from the difficulties in diagnosing and ...
Martin Storr
doaj   +1 more source

Chronic Constipation in the Elderly Patient: Updates in Evaluation and Management

Korean Journal of Family Medicine, 2020
Chronic constipation (CC) is a common disorder in the elderly population globally and is associated with comorbidities and negative implications on the quality of life.
A. Mari, M. Mahamid, Hana Amara, F. Baker, Afif Yaccob   +4 more
semanticscholar   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, Accepted Article.
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, In collaboration with the Consensus Expert Panel (CEP) members   +19 more
wiley   +1 more source

Association of body roundness index with chronic diarrhea and constipation, NHANES 2005–2010

Journal of Health, Population and Nutrition
Background Chronic diarrhea and constipation are known to be associated with obesity. Body roundness index (BRI), as a novel physical dimension assessment indicator, provides a more comprehensive evaluation of body and visceral fat than traditional ...
Yan Zhuang, Laifu Li, Jingyan Sun, Yanqi Zhang, Fei Dai   +4 more
doaj   +1 more source

Association of B vitamins with chronic constipation and diarrhea: a cross-sectional study based on data from NHANES

陆军军医大学学报
Objective To investigate the relationship between daily intake of B vitamins (vitamins B1, B2, B6 and niacin) and chronic constipation and chronic diarrhea.
DING Pei, WANG Lin, WANG Lin
doaj   +1 more source

Ultrasonographic follow-up of functional chronic constipation in adults: A report of two cases

SAGE Open Medical Case Reports, 2017
Chronic constipation is a disorder frequently encountered in clinical practice. Here, we describe the use of ultrasonography as a new approach to the follow-up of adult patients with functional chronic constipation.
Koichi Yabunaka, Gojiro Nakagami, Kazunori Komagata, Hiromi Sanada   +3 more
doaj   +1 more source

Defining constipation to estimate its prevalence in the community: results from a national survey

BMC Gastroenterology, 2019
Background Different definitions of constipation have been used to estimate its prevalence in the community but this creates difficulties when comparing results from various studies.
Barry L. Werth, Kylie A. Williams, Murray J. Fisher, Lisa G. Pont   +3 more
doaj   +1 more source

Chronic Constipation in the United States: Results From a Population-Based Survey Assessing Healthcare Seeking and Use of Pharmacotherapy

American Journal of Gastroenterology, 2020
OBJECTIVES: Chronic idiopathic constipation (CIC) is characterized by unsatisfactory defecation and difficult or infrequent stools. CIC affects 9%–20% of adults in the United States, and although prevalent, gaps in knowledge remain regarding CIC ...
S. Oh, Garth Fuller, Devin B. Patel, Carine Khalil, William Spalding, A. Nag, B. Spiegel, Christopher V. Almario   +7 more
semanticscholar   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source