Results 21 to 30 of about 32,878 (253)

JAK3 as an emerging target for topical treatment of inflammatory skin diseases [PDF]

, 2016
The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Alves de Medeiros, Ana, De Schepper, Sofie, Desmet, Eline, Lambert, Jo, Speeckaert, Reinhart, Van Gele, Mireille   +5 more
core   +6 more sources

Ocular discoid lupus erythematosus: More than what meets the eye

Indian Dermatology Online Journal, 2023
Lupus erythematosus is a spectrum that includes auto-immune disorders such as systemic lupus erythematosus (SLE), subacute cutaneous lupus erythematosus (SCLE), and chronic cutaneous lupus erythematosus (CCLE).
Sumiti Pareek, Alpana Mohta, Rajesh Dutt Mehta, Vijeta Prasad   +3 more
doaj   +1 more source

Chronic Cutaneous Lupus Erythematosus: Depression Burden and Associated Factors. [PDF]

Am J Clin Dermatol, 2019
Depression may occur in up to 30% of individuals with cutaneous lupus erythematosus (CLE), many of whom may also have systemic manifestations. Chronic cutaneous lupus erythematosus (CCLE) conditions are less likely to present systemic involvement than acute and subacute conditions but more often cause permanent scarring and dyspigmentation.
Hong J, Aspey L, Bao G, Haynes T, Lim SS, Drenkard C.   +5 more
europepmc   +4 more sources

B Cell Signatures Distinguish Cutaneous Lupus Erythematosus Subtypes and the Presence of Systemic Disease Activity

Frontiers in Immunology, 2021
Cutaneous lupus erythematosus (CLE) is a chronic inflammatory skin disease characterized by a diverse cadre of clinical presentations. CLE commonly occurs in patients with systemic lupus erythematosus (SLE), and CLE can also develop in the absence of ...
Lisa Abernathy-Close, Stephanie Lazar, Jasmine Stannard, Jasmine Stannard, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi, Sean Eddy, Syed M. Rizvi, Christine M. Yee, Emily M. Myers, Rajaie Namas, Lori Lowe, Lori Lowe, Tamra J. Reed, Fei Wen, Johann E. Gudjonsson, J. Michelle Kahlenberg, Celine C. Berthier   +18 more
doaj   +1 more source

Coexistence of chronic cutaneous lupus erythematosus and frontal fibrosing alopecia. [PDF]

An Bras Dermatol, 2018
Lupus erythemathosus is a chronic, relapsing disease with acute, subacute, and chronic lesions. Effluvium telogen occurs in the setting of systemic activity of the disease, and cicatricial alopecia results from discoid lesionsin on the scalp. Other types of alopecia, like alopecia areata, may rarely be found in lupus.
Nascimento LLD, Enokihara MMSES, Vasconcellos MRA.   +2 more
europepmc   +7 more sources

Chronic cutaneous lupus erythematosus in vitiligo

Dermatology Online Journal, 2008
A 49-year-old woman presented with a seven-year history of pruritic, erythematous, scaling plaques on sun-exposed skin that localized only to pre-existing depigmented patches. Histopathologic examination showed changes consistent with cutaneous lupus erythematosus with lichenoid features and confirmed contiguous vitiligo. Diagnosis of chronic cutaneous
Johnson, Hillary, Bossenbroek, Nicole, Rosenman, Karla, Meehan, Shane A, Robles, Mirin, Pomeranz, Miriam K   +5 more
openaire   +4 more sources

Cutaneous sarcoidosis masquerading as chronic cutaneous lupus erythematosus - case report. [PDF]

BMC Dermatol, 2016
Sarcoidosis is a multisystemic granulomatous disease of unknown origin. Chronic cutaneous lupus erythematosus (CCLE) is an autoimmune disease that is associated with autoantibody production and T-cell dysfunction. Cutaneous manifestations of sarcoidosis may mimic CCLE and vice versa making it difficult to reach a diagnosis clinically.We present a case ...
Vatanchi M, Sobhani K, Fisher VT, Meffert JJ.   +3 more
europepmc   +4 more sources

Pain in systemic connective tissue diseases [PDF]

, 2015
Pain is frequent in patients with connective tissue diseases (CTDs), particularly those affected by systemic sclerosis (SSc) and systemic lupus erythematosus (SLE) in which it is virtually ubiquitous and can have different causes.
Atzeni, Fabiola, Bazzichi, Laura, Casale, Roberto, DI FRANCO, Manuela, Sarzi Puttini, Piercarlo   +4 more
core   +1 more source

Drugs for discoid lupus erythematosus [PDF]

, 2017
BACKGROUND: Discoid lupus erythematosus (DLE) is a chronic form of cutaneous lupus, which can cause scarring. Many drugs have been used to treat this disease and some (such as thalidomide, cyclophosphamide and azathioprine) are potentially toxic. This is
Grainge, Matthew J., Jayasekera, Prativa, Jessop, Sue, Whitelaw, David A.   +3 more
core   +2 more sources

Lupus mastitis and antiphospholipid syndrome treated with anticoagulation and immunosuppression: a case report

Journal of Medical Case Reports, 2023
Background Systemic lupus erythematosus is an autoimmune disease that can have cutaneous and systemic manifestations. Lupus panniculitis, also known as lupus mastitis, is a subset of chronic cutaneous lupus erythematosus that involves inflammation of the
Lauren J. He, Laarni C. Quimson, Oluwakemi Onajin, Kimberly C. Trotter   +3 more
doaj   +1 more source