Results 31 to 40 of about 28,978 (256)

JAK3 as an emerging target for topical treatment of inflammatory skin diseases [PDF]

open access: yes, 2016
The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Alves de Medeiros, Ana   +5 more
core   +23 more sources

Chronic Cutaneous Lupus Erythematosus Presenting with a Buccal Erythema [PDF]

open access: bronzeJournal of Rheumatic Diseases, 2011
Young Jae Oh   +2 more
openalex   +3 more sources

Lupus erythematosus: considerations about clinical, cutaneous and therapeutic aspects [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2014
Systemic Lupus Erythematosus is a chronic inflammatory disease with multifactorial etiology. Although clinical manifestations are varied, the skin is an important target-organ, which contributes to the inclusion of skin lesions in 4 out of the 17 new ...
Jucelio Pereira Moura Filho   +6 more
doaj   +1 more source

Case series of anifrolumab for treatment of cutaneous lupus erythematosus and lupus-related mucocutaneous manifestations in patients with SLE

open access: yesLupus Science and Medicine, 2023
Objective To assess the efficacy of anifrolumab, a type-1 interferon receptor subunit-1 monoclonal antibody, in treating refractory cutaneous lupus erythematosus (CLE) and lupus non-specific mucocutaneous manifestations in patients with systemic lupus ...
Jun Kang, Aaron Bao
doaj   +1 more source

Cutaneous lupus erythematosus: a review of etiopathogenic, clinical, diagnostic and therapeutic aspects

open access: yesAnais Brasileiros de Dermatologia, 2023
Cutaneous lupus erythematosus is an autoimmune disease of varied clinical expression, which may present as an exclusively cutaneous disease or be one of the multiple manifestations of systemic lupus erythematosus.
Everton Carlos Siviero do Vale   +1 more
doaj   +1 more source

Panoramic view of clinical features of lupus erythematosus: a cross-sectional multicentre study from China

open access: yesLupus Science and Medicine, 2023
Objective Lupus erythematosus (LE) is a complicated disease with highly heterogeneous clinical manifestations. Previous studies have rarely included all subgroups of patients with lupus and have overlooked the importance of the cutaneous manifestations ...
Qing Zhang   +19 more
doaj   +1 more source

Ocular discoid lupus erythematosus: More than what meets the eye

open access: yesIndian Dermatology Online Journal, 2023
Lupus erythematosus is a spectrum that includes auto-immune disorders such as systemic lupus erythematosus (SLE), subacute cutaneous lupus erythematosus (SCLE), and chronic cutaneous lupus erythematosus (CCLE).
Sumiti Pareek   +3 more
doaj   +1 more source

Current concepts of photosensitivity in cutaneous lupus erythematosus

open access: yesFrontiers in Medicine, 2022
Cutaneous lupus erythematosus (CLE) represents a complex autoimmune disease with a broad phenotypic spectrum ranging from acute to chronic destructive cutaneous lesions. Patients with CLE exhibit high photosensitivity and ultraviolet (UV) irradiation can
Benjamin Klein, Manfred Kunz
doaj   +1 more source

B Cell Signatures Distinguish Cutaneous Lupus Erythematosus Subtypes and the Presence of Systemic Disease Activity

open access: yesFrontiers in Immunology, 2021
Cutaneous lupus erythematosus (CLE) is a chronic inflammatory skin disease characterized by a diverse cadre of clinical presentations. CLE commonly occurs in patients with systemic lupus erythematosus (SLE), and CLE can also develop in the absence of ...
Lisa Abernathy-Close   +18 more
doaj   +1 more source

Clinical periodontal diagnosis

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi   +5 more
wiley   +1 more source

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