Results 31 to 40 of about 32,878 (253)

Brief report: Responses to rituximab suggest B cell-independent inflammation in cutaneous systemic lupus erythematosus [PDF]

, 2015
Objective The immunopathogenesis of systemic lupus erythematosus (SLE) is heterogeneous, and responses of skin to rituximab are variable. This study was undertaken to determine the phenotype of rituximab-responsive disease.
Berggren, Bruce, Isenberg, Kuhn, Md Yusof, Perez-Ferro, RD, Savarese, Sontheimer, Vital, Vital, Vollenhoven, Wenzel, Wittmann, Yee   +14 more
core   +1 more source

Heterogeneous lupus‐specific lesions and treatment outcome, in a single patient, over a period of time [PDF]

, 2019
The report highlights the importance of strict clinico-histological correlations when skin biopsies are performed in diagnostic doubt in systemic lupus erythematosus.
Agostini, Patrick, Fernandes, Melissa, Moraes-Fontes, Maria Francisca, Riso, Nuno, Taulaigo, Anna V., Vidal, Carolina   +5 more
core   +2 more sources

Systemic lupus erythematosus with generalized chronic cutaneous (discoid) lupus erythematosus

Dermatology Online Journal, 2008
A 24-year-old pregnant African-American woman had a 3-4 year history of chronic, scarring, hyperpigmented plaques on her scalp, face, trunk, and extremities. She complained of joint pain and fatigue. Clinical presentation, laboratory data, and histopathologic features were consistent with systemic lupus erythematosus in a patient with generalized ...
Dadlani, Chicky, Pulitzer, Melissa, Prystowsky, Stephen D   +2 more
openaire   +4 more sources

Audio-vestibular symptoms in systemic autoimmune diseases [PDF]

, 2018
Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss
Adelchi, Croce, D'AGUANNO, VITTORIO, DE VINCENTIIS, Marco, DE VIRGILIO, ARMANDO, DI STADIO, Arianna, GRECO, Antonio, LONGO, Lucia, RALLI, MASSIMO   +7 more
core   +1 more source

Low expression of estrogen receptor β in T lymphocytes and high serum levels of anti-estrogen receptor α antibodies impact disease activity in female patients with systemic lupus erythematosus [PDF]

, 2016
BACKGROUND: Current evidence indicates that estrogens, in particular 17β-estradiol (E2), play a crucial role in the gender bias of autoimmune diseases although the underlying molecular mechanisms have not yet been fully elucidated.
ALESSANDRI, cristiano, BARBATI, CRISTIANA, Ciarlo, Laura, COLASANTI, TANIA, CONTI, FABRIZIO, Maselli, Angela, Ortona, Elena, Patrizio, Mario, Pierdominici, Marina, SPINELLI, FRANCESCA ROMANA, VALESINI, Guido, VOMERO, MARTA   +11 more
core   +1 more source

Systemic Lupus Erythematosus Presented with Bilateral Orbital Edema and Negative Serology

Case Reports in Rheumatology, 2019
Isolated bilateral periorbital edema with negative serology is an extremely rare presentation of cutaneous lupus erythematosus that may lead to eyelid scarring, infection, or even corneal involvement.
Manal Al-Khaldi, Manal Alsabbagh
doaj   +1 more source

TREX1 DNA exonuclease deficiency, accumulation of single stranded DNA and complex human genetic disorders [PDF]

, 2008
Aicardi-Goutieres syndrome (AGS) is an unusual condition that clinically mimics a congenital viral infection. Several genes have recently been implicated in the aetiology of this disorder. One of these genes encodes the DNA exonuclease TREX1. Recent work
Aicardi, Akira, Alderton, Alderton, Bartek, Bartkova, Brennan, Brucet, Chen, Chowdhury, Crow, Crow, de Silva, DiTullio, Driscoll, Gasser, Griffith, Griffiths, Höss, Jazayeri, Kawai, Lee-Kirsch, Lee-Kirsch, Lieberman, Lieberman, Lindahl, Lindahl, Liu, Liu, Liu, Mark O’Driscoll, Martinvalet, Mazur, Mazur, Morita, Napirei, O’Driscoll, O’Driscoll, Qiu, Raulet, Rhodes, Rice, Richards, Shevelev, Stiff, Stiff, Takaoka, Tran, Tsukumo, Vyse, Walport, Yang, Yasutomo, Zou, Zou   +54 more
core   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

Lupus profundus limited to a site of trauma: Case report and review of the literature

International Journal of Women's Dermatology, 2017
Lupus erythematosus profundus (LEP) is a rare form of chronic cutaneous lupus erythematosus. We report on a case of a 56-year-old Caucasian woman who presented with a single, persistent, painful rash on the left hip and lateral aspect of the left upper ...
María Adriana Castrillón, MD, Dédée F. Murrell, MA, BMBCh, MD, FAAD, FACD, FRCP (Edin)   +1 more
doaj   +1 more source

Cryoglobulinaemic vasculitis: classification and clinical and therapeutic aspects [PDF]

, 2007
Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection.
Braun, Gerald S., Horster, Sophia, Ihrler, Stephan, Schmid, Holger, Wagner, Katrin S.   +4 more
core   +2 more sources