Results 71 to 80 of about 2,952,772 (291)

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Applied Indicators in Treatment Approaches of Chronic Depressive Disorders

Taḥqīqāt-i ̒Ulūm-i Raftārī, 2017
Aim and Background: The number of previous studies on the subject of specific treatments for chronic depression disorders was limited and significantly incomplete.
سید محمدرضا صمصام شریعت, حمید طاهر نشاط‌دوست, مهرداد کلانتری, سید حمیدرضا عریضی سامانی   +3 more
doaj  

Chronic disease comorbidities among middle-aged and elderly Chinese population with different depression levels: a network analysis on 2018 CHARLS data

Zhongguo gonggong weisheng
ObjectiveTo understand the chronic disease comorbidities among middle-aged and elderly Chinese population with different depression levels and provide a scientific basis for optimizing depression screening and chronic disease prevention and treatment ...
Qiaofeng LI, Yilong YAN, Yuehan HE, Yongtai LI, Guowu DING   +4 more
doaj   +1 more source

Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu, Tianxue Chen, Wei Jin, Weifeng Jin, Haitong Wan   +4 more
wiley   +1 more source

Prevention of major depression in complex medically ill patients: preliminary results from a randomized, controlled trial [PDF]

, 2009
Background: Depression is highly prevalent in patients with physical illness and is associated with a diminished quality of life and poorer medical outcomes.
Stiefel, F.C., de Jonge, Peter; id_orcid, Dorogi, Yves, Hadj, Fatima Bel, Boffa, Daria, Boffa, D., So, A., Dorogi, Y., So, Alexander, de Jonge, P., Stiefel, Friedrich, Zdrojewski, Catherine, Zdrojewski, C., Stiefel, F., de Jonge, Peter, Ruiz, Juan, Ruiz, J., Hadj, F.B.   +17 more
core   +2 more sources

Mucocutaneous Disease Activity and Damage Accrual in Systemic Lupus Erythematosus: Analyses From the Asia‐Pacific Lupus Collaboration Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective This research article aims to describe the prevalence, associations, and health‐related quality of life (HRQoL) impact of mucocutaneous features of systemic lupus erythematosus (SLE). Methods Data from the Asia‐Pacific Lupus Collaboration cohort were analyzed (2013–2021).
Amanda M. Saracino, Yanjie Hao, Dylan Hansen, Yi‐Hsing Chen, Alberta Hoi, Vera Golder, Jiacai Cho, Aisha Lateef, Worawit Louthrenoo, Laniyati Hamijoyo, Shue Fen Luo, Yeong‐Jian Jan Wu, Sandra Navarra, Leonid Zamora, Chak Sing Lau, Shirley Chan, Zhanguo Li, Hai‐hong Yao, Sargunan Sockalingam, B. M. D. B. Basnayake, Yasuhiro Katsumata, Masayoshi Harigai, Zhuoli Zhang, Jun Kikuchi, Yuko Kaneko, Tsutomu Takeuchi, Madelynn Chan, Sang‐Cheol Bae, Fiona Goldblatt, Sean O'Neill, Geraldine Hassett, Kristine Ng, Nicola Tugnet, Mark Sapsford, Yih Jia Poh, Michael Tee, Cherica Tee, Naoaki Ohkubo, Yoshiya Tanaka, Rangi Kandane‐Rathnayake, Eric Morand, Shereen Oon, Mandana Nikpour   +42 more
wiley   +1 more source

Inhibitory synaptic transmissions to the bed nucleus of the stria terminalis neurons projecting to the ventral tegmental area are enhanced in rats exposed to chronic mild stress

Molecular Brain, 2020
The comorbidities of depression and chronic pain have long been recognized in the clinic, and several preclinical studies have demonstrated depression-like behaviors in animal models of chronic pain.
Ryuto Hara, Daiki Takahashi, Tatsuhiro Takehara, Taiju Amano, Masabumi Minami   +4 more
doaj   +1 more source

Biopsychosocial Determinants of Hand Function and Its Trajectories Over Five Years in Patients With Hand Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective This study aimed to investigate hand function trajectories over five years in primary hand osteoarthritis (OA). Additionally, determinants of baseline and longitudinal hand function were assessed. Methods A total of 538 patients with both baseline and five‐year study visits were analyzed.
Annemiek V. E. M. Olde Meule, Coen van der Meulen, Jos Runhaar, Frits R. Rosendaal, Margreet Kloppenburg   +4 more
wiley   +1 more source

Anhedonia in the shadow of chronic social defeat stress, or When the experimental context matters [PDF]

, 2008
One of the core symptoms of major depression in human is anhedonia. For that reason, one of the main requirements towards experimental depression models is that they be able to demonstrate anhedonia in animals, that have been exposed to stressful events,
Dmitry A. Smagin, Damira F. Avgustinovich, Irina L. Kovalenko, Natalia N. Kudryavtseva, Natalia P. Bondar   +4 more
core  

Depression and cancer: physiological and psychological markers [PDF]

, 2010
PhDAim: To investigate potential markers for depression and poor quality of life (QoL) in head and neck (HN) and colorectal (CR) cancer patients. Background: Comorbid depression is strongly related to decreased QoL in cancer patients and may increase ...
Archer, Josephine Astrid
core   +4 more sources