Results 131 to 140 of about 14,641,362 (427)

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Application value of contrast‐enhanced ultrasound in preoperative localization of microwave ablation for primary hyperparathyroidism

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Background Ultrasonography (US) and 99mTechnetium‐sestamibi scintigraphy (99mTc‐MIBI) are currently first‐line imaging modalities to localize parathyroid adenomas with sensitivities of 80% and 84%, respectively. Therefore, finding other modalities to further improve the diagnostic accuracy for preoperative localization is critically needed ...
Fangyi Liu   +7 more
wiley   +1 more source

High MTHFR promoter methylation levels in men confer protection against ischemic stroke

open access: yesBiomolecules & Biomedicine, 2020
The MTHFR gene encodes methylenetetrahydrofolate reductase required for the metabolism of homocysteine (Hcy) – a previously reported independent risk factor for ischemic stroke (IS).
Shan Xu   +10 more
doaj   +1 more source

2013 Cherokee County Obesity Fact Sheet [PDF]

open access: yes, 2013
This fact sheet provides information on nutrition, physical activity, and obesity for Cherokee ...
Department of Health and Environmental Control, Division of Chronic Disease Epidemiology
core  

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

2013 Laurens County Obesity Fact Sheet [PDF]

open access: yes, 2013
This fact sheet provides information on nutrition, physical activity, and obesity for Laurens ...
Department of Health and Environmental Control, Division of Chronic Disease Epidemiology
core  

Primary nonadherence to chronic disease medications: a meta-analysis

open access: yesPatient Preference and Adherence, 2018
Background Medication nonadherence is a global problem that requires urgent attention. Primary nonadherence occurs when a patient consults with a medical doctor, receives a referral for medical therapy but never fills the first dispensation for the ...
M. Lemstra   +3 more
semanticscholar   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Prevalence and patterns of chronic disease multimorbidity and associated determinants in Canada

open access: yesHealth Promotion and Chronic Disease Prevention in Canada, 2015
Introduction: Multimorbidity is increasingly recognized as a key issue in the prevention and management of chronic diseases. We examined the prevalence and correlates of chronic disease multimorbidity in the general adult Canadian population in relation ...
K. C. Roberts   +4 more
doaj   +1 more source

2013 McCormick County Obesity Fact Sheet [PDF]

open access: yes, 2013
This fact sheet provides information on nutrition, physical activity, and obesity for McCormick ...
Department of Health and Environmental Control, Division of Chronic Disease Epidemiology
core  

Home - About - Disclaimer - Privacy