Results 131 to 140 of about 5,016,105 (350)

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Status and associated factors of food and nutrition literacy among young adults aged 15–44 years in Shenzhen City, China

Frontiers in Public Health
BackgroundFood and nutrition literacy (FNL) plays an important role in young adults’ dietary habits and nutrition. This study aimed to investigate FNL status and its associated factors among young adults aged 15–44 years in Shenzhen.MethodsA cross ...
Li Zhixue, Xu Ying, Liu Zheng, Ma Yan, Guo Yanfang, Wang Dewang, Yu Weijun, Zhao Rencheng, Yuan Qing, Xu Meihong   +9 more
doaj   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Susceptibility to e-cigarette adoption among tobacco-naïve youths: a cross-sectional study in Shenzhen, China

Frontiers in Public Health
BackgroundThe rise in e-cigarette use among youth is a significant global public health issue. It is important to identify those at increased risk and implement effective strategies to reduce e-cigarette popularity among the youth.ObjectiveThis study ...
Ruilin Yan, Yanhong Liu, Li Huang, Yanrou Li, Yun Huang, Jing Tong, Yongzheng Deng, Qing Yuan   +7 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Chronic kidney disease [PDF]

BMJ, 2007
Prabir Kumar, Mitra, Peter R W, Tasker, M S, Ell   +2 more
openaire   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Oral health service utilization and treatment costs for oral diseases among residents in Shenzhen city

Zhongguo gonggong weisheng
ObjectiveTo understand the utilization of oral health services and the cost of oral disease treatment among residents in Shenzhen city, Guangdong province, and to provide a reference for monitoring and evaluating oral health care work in Shenzhen city ...
Dan CUI, Peng XUAN, Xiaochun CHEN, Kuizhong LIU, Shuhua ZHAO, Yuanhang ZHOU, Zhongqian YANG, Mingqiu YANG, Rui ZOU, Junxi HONG, Juhong LI   +10 more
doaj   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Comparison of novel and traditional anthropometric indices in Eastern-China adults: which is the best indicator of the metabolically obese normal weight phenotype?

BMC Public Health
Background People with the metabolically obese normal weight (MONW) phenotype have been confirmed to significantly increase the risk of unfavorable health consequences.
Yijia Chen, Chenchen Wang, Qiannan Sun, Qing Ye, Hairong Zhou, Zhenzhen Qin, Shengxiang Qi, Weiwei Wang, Xin Hong   +8 more
doaj   +1 more source