Results 211 to 220 of about 8,726,957 (297)

Determinants of care modality and chronic disease needs among older adults with chronic disease and disability in rural China: a cross-sectional study in Qinghe County, Hebei Province. [PDF]

BMJ Open
Geng J, Kang Y, Liu Y, Liu X, Sun Y.
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

The Need for Community-Based Multimodal Screening for Chronic Disease and Cancer in Rural Kansas. [PDF]

Int J Gen Med
Neely JA, Schmidt JR, Ziaei ES, Elliott KG, Durrett RD, McMann L, Ventura CAI.   +6 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Editorial: Transforming chronic disease treatment with AI and big data. [PDF]

Front Mol Biosci
Xing X, Sun Z, Yang K, Wei S.
europepmc   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

The Meaning of Chronic Disease Management in the Patient's Environment: A Critical Ethnographic Study. [PDF]

Healthcare (Basel)
Loizeau V, Nohra RG, Pougheon-Bertrand D, Rothan-Tondeur M.   +3 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Inflammation and Chronic Disease: The Mediterranean Diet in Precision and Personalized Nutrition.

Ann Nutr Metab
Cuevas-Sierra A, Tomé-Carneiro J, Marques da Silva MM, Tavares da Silva MI, de Cuevillas B, Silvestre MP, Martínez JA.   +6 more
europepmc   +1 more source

Adaptation and validation of the chronic disease helplessness survey for Chinese patients with chronic conditions. [PDF]

BMC Psychiatry
Huang B, Tang J, Guo Z, Chen Y, Zhou L, Zhang F, Zhao Q, Zhao H.   +7 more
europepmc   +1 more source