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Anemi ved kronisk sykdom er i Vesten den vanligste formen for anemi hos hospitaliserte pasienter over 50 år. Diagnostikken kompliseres av at de klassiske biokjemiske parametrene, brukt til vurdering av jernstatus, påvirkes av immunaktiveringen som er ...
I. M. Hardang, K. Lilleholt, T. Hagve
semanticscholar +1 more source
Chronic diseases in adolescence [PDF]
Introduction. The prevalence of chronic diseases in adolescence is constantly increasing, especially in the last two decades. Adolescence is a period of important changes: body growth and development, sexual development, development of cognitive abilities, change in family relations and between peers, formation of personal identity and personal system ...
Irena Odri+2 more
openaire +3 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
2013 Greenwood County Obesity Fact Sheet [PDF]
This fact sheet provides information on nutrition, physical activity, and obesity for Greenwood ...
Department of Health and Environmental Control, Division of Chronic Disease Epidemiology
core +3 more sources
Predicting Development of Chronic Obstructive Pulmonary Disease and its Risk Factor Analysis [PDF]
Chronic Obstructive Pulmonary Disease (COPD) is an irreversible airway obstruction with a high societal burden. Although smoking is known to be the biggest risk factor, additional components need to be considered. In this study, we aim to identify COPD risk factors by applying machine learning models that integrate sociodemographic, clinical, and ...
arxiv
Background Multimorbidity–having two or more coexisting chronic conditions–is highly prevalent, costly, and disabling to older adults. Questions remain regarding chronic diseases accumulation over time and whether this differs by racial and ethnic ...
Ana R. Quiñones+6 more
semanticscholar +1 more source
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung+6 more
wiley +1 more source
Food based dietary patterns and chronic disease prevention
Matthias B Schulze and colleagues discuss current knowledge on the associations between dietary patterns and cancer, coronary heart disease, stroke, and type 2 diabetes, focusing on areas of uncertainty and future research ...
M. Schulze+4 more
semanticscholar +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Background This study aimed to investigate the prevalence of multimorbidity and its associated factors among the older population in China to propose policy recommendations for the management of chronic diseases in older adults.
Wenqing Ni+5 more
doaj +1 more source