Results 61 to 70 of about 4,214,463 (259)

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

Molecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol   +3 more
wiley   +1 more source

2013 Anderson County Obesity Fact Sheet [PDF]

, 2013
This fact sheet provides information on nutrition, physical activity, and obesity for Anderson ...
Department of Health and Environmental Control, Division of Chronic Disease Epidemiology
core  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

An Assessment of Funding and Other Capacity Needs for Health Equity Programming Within State-Level Chronic Disease Programs

, 2017
Background: Chronic diseases are an important contributor to morbidity and mortality among racial/ethnic minority, low-income, and other under-resourced populations.
Adunola, DDS, MPH, Folasaya, Brandt, EdD, MPH, Gail, Delavan, BA, JamieLou, New, OTR, MPH, Marisa, Nweke, Onyemaechi, Pertillar, Tiffany, Pobutsky, PhD, Ann, Shah, MPA, MA, Amishi, Taylor, MBA, Robyn   +8 more
core  

2013 Horry County Obesity Fact Sheet [PDF]

, 2013
This fact sheet provides information on nutrition, physical activity, and obesity for Horry ...
Department of Health and Environmental Control, Division of Chronic Disease Epidemiology
core  

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Chronic Disease and Risk Factors among Nevadans with Disabilities: A 2009 BRFSS Study

, 2012
Previous research has found that people with disabilities are more likely to have chronic diseases (coronary artery disease, stroke, cancer, asthma, diabetes), secondary conditions (high blood pressure, high cholesterol) and risk factors for chronic ...
Moonie, Sheniz, Pharr, Jennifer R.
core  

2013 Georgetown County Obesity Fact Sheet [PDF]

, 2013
This fact sheet provides information on nutrition, physical activity, and obesity for Georgetown ...
Department of Health and Environmental Control, Division of Chronic Disease Epidemiology
core   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

2013 York County Obesity Fact Sheet [PDF]

, 2013
This fact sheet provides information on nutrition, physical activity, and obesity for York ...
Department of Health and Environmental Control, Division of Chronic Disease Epidemiology
core