Results 61 to 70 of about 4,780,614 (352)

Prevalence of disability according to multimorbidity and disease clustering: a population-based study [PDF]

, 2011
Background: The prevalence of chronic diseases has increased with population ageing, and research has attempted to elucidate the correlation between chronic diseases and disability. However, most studies in older populations have focused on the effect of
Angleman, Sara, Fratiglioni, Laura, Marengoni, Alessandra   +2 more
core   +1 more source

Sociodemographic and lifestyle determinants of multimorbidity among community-dwelling older adults: findings from 346,760 SHARE participants

BMC Geriatrics, 2023
Background This study aimed to investigate the prevalence of multimorbidity and its associated factors among the older population in China to propose policy recommendations for the management of chronic diseases in older adults.
Wenqing Ni, Xueli Yuan, Yan Zhang, Hongmin Zhang, Yijing Zheng, Jian Xu   +5 more
doaj   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Prediction of disease progression, treatment response and dropout in chronic obstructive pulmonary disease (COPD). [PDF]

, 2014
Drug development in chronic obstructive pulmonary disease (COPD) has been characterised by unacceptably high failure rates. In addition to the poor sensitivity in forced expiratory volume in one second (FEV1), numerous causes are known to contribute to ...
Danhof, M, Della Pasqua, O, Facius, A, Maas, HJ, Musuamba, FT, Teutonico, D, Yang, S   +6 more
core   +1 more source

Readmissions Following a Hospitalization for Cardiovascular Events in Dialysis Patients: A Retrospective Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundHospitalization for cardiovascular disease (CVD) is common among patients receiving maintenance dialysis, but patterns of readmissions following cardiovascular events are underexplored.
James B. Wetmore, Julia T. Molony, Jiannong Liu, Yi Peng, Charles A. Herzog, Allan J. Collins, David T. Gilbertson   +6 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Assessing chronic disease management in European health systems. Country reports [PDF]

, 2015
Many countries are exploring innovative approaches to redesign delivery systems to provide appropriate support to people with long-standing health problems.
Knai, C, Nolte, E
core  

Prevalence, treatment patterns, and healthcare resource utilization in Medicare and commercially insured non-dialysis-dependent chronic kidney disease patients with and without anemia in the United States

BMC Nephrology, 2018
Background Anemia is common in non-dialysis-dependent chronic kidney disease (NDD-CKD) patients, but detailed information on prevalence and treatment is lacking.
Wendy L. St. Peter, Haifeng Guo, Shaum Kabadi, David T. Gilbertson, Yi Peng, Trudy Pendergraft, Suying Li   +6 more
doaj   +1 more source

Chronic kidney disease

South African Medical Journal, 2015
It is known that, for many reasons, general practitioners(GPs) find renal disease difficult to diagnose, understandand treat. The terms chronic kidney disease (CKD) andglomerular filtration rate (GFR), representing the renalfunction equation, have been introduced to clarify someof these difficulties.
openaire   +7 more sources