Results 61 to 70 of about 16,563 (182)

The safe and effective use of tofacitinib and ustekinumab combination therapy in infantile onset inflammatory bowel disease

JPGN Reports, EarlyView.
Abstract Infantile‐onset inflammatory bowel disease (IOIBD) is a rare and severe subset of very‐early‐onset IBD, often associated with immune dysregulation and poor response to conventional therapies. Data regarding the use of Janus kinase inhibitors (JAKI) in this population is limited.
Smridhi Mahajan, Christian Wysocki, Bhaskar Gurram   +2 more
wiley   +1 more source

Cyclooxygenase-2 and 5-Lipoxygenase in Dogs with Chronic Enteropathies [PDF]

Journal of Veterinary Internal Medicine, 2014
Abstract Background Cyclooxygenase-2 (COX-2) is a key enzyme in the synthesis of pro-inflammatory prostaglandins and 5-lipoxygenase (5-LO) is the major source of leukotrienes. Their role in IBD has been demonstrated in humans and animal models, but not in dogs with chronic enteropathies (CCE).
Dumusc, S D, Ontsouka, E C, Schnyder, M, Hartnack, S, Albrecht, C, Bruckmaier, R M, Burgener, I A   +6 more
openaire   +4 more sources

Refractory Eczema as a Presenting Feature of Common Variable Immunodeficiency

JEADV Clinical Practice, EarlyView.
ABSTRACT Common variable immunodeficiency (CVID) is the most prevalent symptomatic inborn error of immunity (IEI) in adults. It presents with recurrent infections and non‐infectious complications, including autoimmunity, lymphoproliferation and dermatitis.
Mercedes Sanchez‐Diaz, Lars Matthies, Andrea Vanegas Ramirez   +2 more
wiley   +1 more source

Hierarchical modelling of immunoglobulin coated bacteria in dogs with chronic enteropathy shows reduction in coating with disease remission but marked inter-individual and treatment-response variability.

PLoS ONE, 2021
Chronic enteropathies are a common problem in dogs, but many aspects of the pathogenesis remain unknown, making the therapeutic approach challenging in some cases.
Lina María Martínez-López, Alexis Perez-Gonzalez, Elizabeth Ann Washington, Andrew P Woodward, Alexandra Jazmin Roth-Schulze, Julien R S Dandrieux, Thurid Johnstone, Nathalee Prakash, Aaron Jex, Caroline Mansfield   +9 more
doaj   +1 more source

Nail Disorders in Systemic Conditions

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail findings in children can be indicative of an underlying systemic disease. Many of these findings are seen in multiple entities and are not specific to one disease. The importance of specifically examining for these nail changes cannot be overstated.
Jane Sanders Bellet
wiley   +1 more source

Spruelike Enteropathy Associated with Olmesartan: An Unusual Case of Severe Diarrhea

Case Reports in Gastrointestinal Medicine, 2013
A 64-year-old male with a history of hypertension presented with worsening diarrhea and 25-pound weight loss over the preceding three months. Prior screening colonoscopy was unremarkable, and the patient failed conservative management.
Stephanie E. Dreifuss, Yutaka Tomizawa, Nicholas J. Farber, Jon M. Davison, Adam E. Sohnen   +4 more
doaj   +1 more source

Chronic Intestinal Failure During the Neonatal Period Related to Height at Five Years of Age

Acta Paediatrica, EarlyView.
ABSTRACT Aim To clarify if children with chronic intestinal failure during the neonatal period had a different height at 5 years of age compared to standardised Swedish growth charts. Methods This retrospective cohort study of children with chronic intestinal failure during the neonatal period in Gothenburg between 2004 and 2018.
Johanna Mårtenson, Helena Borg, Julius Kristjansson, Anton Holmgren, Nils Ekvall, Anders Elfvin   +5 more
wiley   +1 more source

A rare cause of congenital diarrhea in a Turkish newborn: tufting enteropathy

The Turkish Journal of Pediatrics, 2014
Tufting enteropathy is an autosomal recessive congenital enteropathy presenting with early-onset severe intractable diarrhea. It presents with watery diarrhea that develops in the first days after birth and persists despite bowel rest.
Dilek Kahvecioğlu, Resul Yılmaz, Arzu Ensari, Begüm Atasay, Zarife Kuloğlu, Ömer Erdeve, Banu İnce-Alkan, Atilla Kılıç, Duran Yıldız, Saadet Arsan   +9 more
doaj  

Oral Cobalamin Supplementation in Dogs with Chronic Enteropathies and Hypocobalaminemia [PDF]

Journal of Veterinary Internal Medicine, 2016
Abstract Background Cobalamin deficiency is commonly associated with chronic enteropathies (CE) in dogs and current treatment protocols recommend parenteral supplementation. In humans, several studies have reported equal efficacy of oral and parenteral cobalamin administration of cobalamin.
Toresson, L., Steiner, J. M., Suchodolski, J. S., Spillmann, T.   +3 more
openaire   +3 more sources

The benefits of multidisciplinary collaboration in the successful management of two complex feline cases

Australian Veterinary Journal, EarlyView.
Despite a frequent misconception that behavioural concerns are diagnoses of exclusion, medical conditions and behavioural disorders are frequently inter‐related. In human medicine, the ‘multidisciplinary team’ approach (MDTA) is considered the most efficacious way of managing patients with complex and chronic health conditions.
BE Bollaert, JM Ley, HE Zulch
wiley   +1 more source