Results 81 to 90 of about 336,027 (339)
ごく最近,慢性疲労症候群, (chronic fatigue syndrome: CFS)が新しい疾患概念として社会的な話題となっている.著しい疲労感のため日常生活すら不能にしてしまうという症状を主徴としたこの疾患は欧米では早くから知られていたが,心因を基盤とした精神科領域の疾患とみなされていた. 1930年頃より集団発生がみられ,一層注目されることとなった.その後,各種の感染症の後にこの病態を示す例があることが知られ,特にウイルス感染に伴う器質的疾患という見方が次第に台頭してきた.しかし今までのところいくつかの病因候補ウイルスはあげられているものの,未だ病因は不明である.
openaire +3 more sources
Fibromyalgia is a chronic musculoskeletal disorder which results in widespread pain, fatigue, cognitive difficulties, and emotional distress (CDC, 2017). It is also associated with abnormal pain processing.
Glennon, McKenzie K.
core +1 more source
Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses [PDF]
The genesis of severe fatigue and disability in people following acute pathogen invasion involves the activation of Toll-like receptors followed by the upregulation of proinflammatory cytokines and the activation of microglia and astrocytes.
Berk, Michael +3 more
core +2 more sources
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo +19 more
wiley +1 more source
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Mechanisms underlying fatigue: a voxel-based morphometric study of chronic fatigue syndrome
Background Fatigue is a crucial sensation that triggers rest, yet its underlying neuronal mechanisms remain unclear. Intense long-term fatigue is a symptom of chronic fatigue syndrome, which is used as a model to study the mechanisms underlying fatigue ...
Watanabe Yasuyoshi +4 more
doaj +1 more source
Cognitive Behavioral Therapy for Youth with Childhood‐Onset Lupus: A Randomized Clinical Trial
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham +29 more
wiley +1 more source
This study compared the clinical effectiveness and treatment satisfaction of Pregabalin and Gabapentin triple therapy for neuropathic pain in a real‐world setting. The primary outcome measured the reduction in mean Self‐Administered Leeds Assessment of Neuropathic Symptoms and Signs pain score value from baseline to 12 weeks posttreatment.
Nithya Raju +7 more
wiley +1 more source
Chronic fatigue syndrome and cases of idiopathic intracranial hypertension without signs of raised intracranial pressure can be impossible to distinguish without direct measurement of intracranial pressure.
Nicholas Higgins +2 more
doaj +1 more source
Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu +109 more
wiley +1 more source

