Results 41 to 50 of about 55,598 (274)

Antibacterial Micro/Nanorobots: Innovations, Challenges, and Future Perspectives in Combatting Infection

open access: yesNano Select, EarlyView.
Antibacterial micro/nanorobots (MNRs) represent a breakthrough in antibacterial therapy, making precise delivery of drugs to the infection site. This review systematically summarizes the material composition, actuation, and applications of MNRs in combating biofilms and drug‐resistant infections while emphasizing the existing challenges of ...
Yichao Chen   +4 more
wiley   +1 more source

Histopathological Studies on Chronic Gastritis Associated with Helicobacter pylori Infection from Rural Area of India [PDF]

open access: yesJournal of Krishna Institute of Medical Sciences University, 2016
Background: Helicobacter pylori infection has been implicated as a major cause of chronic gastritis. It has been categorized as class 1 carcinogen. Aim and Objectives: An attempt has been made to evaluate the incidence of H.
Smita Bhosale   +4 more
doaj  

Single‐cell RNA sequencing revealed the T‐cell heterogeneity and exhaustion subsets of Helicobacter pylori‐induced gastritis‐to‐cancer transformation

open access: yesVIEW, EarlyView.
H. pylori infection is a major cause of stomach cancer, but its effect on immune cells in tumors is unclear. Using single‐cell sequencing, we mapped the stomach tumor environment and discovered a specific exhausted T‐cell subtype, marked by the FYB1 gene, that is abundant in H. pylori‐positive tumors and linked to patient prognosis. Our findings reveal
Yanhui Yang   +22 more
wiley   +1 more source

Resveratrol attenuates areca nut extract‐induced chronic colitis by suppressing pyroptosis of intestinal epithelial cells via modulating cGAS/STING signaling

open access: yesVIEW, EarlyView.
Areca nut extract (ANE), commonly consumed in some cultures, can damage gut cells by triggering inflammation and cell death through a pathway called cGAS‐STING. This leads to the release of harmful inflammatory substances and weakens the gut barrier. Our study shows that resveratrol, a natural compound found in foods like grapes, can block this harmful
Jing Zhang   +4 more
wiley   +1 more source

Conservation Status, Decline Factors, and Strategies for Globally Endangered Musk Deer (Moschus spp.) in China 中国境内全球濒危麝属 (Moschus spp.) 物种的保护现状、致危因素及应对策略

open access: yesWildlife Letters, EarlyView.
This review summarizes the status of musk deer in China, highlighting severe population declines due to illegal hunting and habitat loss, and proposes integrated conservation strategies including habitat protection, captive breeding, and law enforcement to support the recovery and sustainable management of this ecologically and economically important ...
Feng Jiang   +8 more
wiley   +1 more source

Elevated beta‐hydroxybutyrate within a pediatric population and its associated pathology: A retrospective case series

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Elevated beta‐hydroxybutyrate (BHB) is a marker for ketoacidosis. Post‐mortem values for the diagnosis of fatal ketoacidosis and the associated clinical and histologic findings are limited in the pediatric population. A retrospective case series of pediatric autopsy records and histology slides was conducted.
Nasim Haghandish   +3 more
wiley   +1 more source

Adherence to Mediterranean Diet During Pregnancy, Breastfeeding, and Development of Food Allergy in the Offspring: Results From the MEDALLION Cohort Study

open access: yesAllergy, EarlyView.
This study analyzed data from a sub‐cohort of the MEDALLION study to examine the association between maternal adherence to the Mediterranean diet and the development of food allergy in offspring. Maternal dietary intake during pregnancy and lactation was assessed using the validated MedDiet Score, together with individual food group consumption ...
Emilia Vassilopoulou   +11 more
wiley   +1 more source

Review Article: Classic Bismuth Quadruple Therapy for Helicobacter pylori Infection—Questions Focused on Clinical Practice

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
BQT remains the most effective, safe, and practical regimen for H. pylori eradication, ensuring high cure rates across diverse resistance patterns and clinical settings. ABSTRACT Background Classic bismuth quadruple therapy (BQT)—the combination of a proton pump inhibitor, bismuth, tetracycline, and metronidazole—is a standard regimen for treating ...
Javier P. Gisbert   +2 more
wiley   +1 more source

Spectrum of Chronic Gastritis Based on Morphological Examination of Gastric Biopsies

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: in the retrospective study to assess the frequency of various gastritis variants based on the results of morphological examination of gastric biopsies over a 5-year observation period.Methods.
А. S. Tertychnyy   +8 more
doaj   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

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