Results 121 to 130 of about 90,641 (290)

Interleukin (IL)‐5, Eosinophils and IL‐5 Pathway Inhibitors in Eosinophilic Granulomatosis with Polyangiitis.

Arthritis &Rheumatology, Accepted Article.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

Therapeutic Gene Editing: DNA Repair Pathways, Emerging Editors, and Clinical Progress

iNew Medicine, EarlyView.
ABSTRACT The field of gene editing has evolved rapidly over the past decade, progressing from programmable zinc‐finger nucleases (ZFNs) and transcription activator‐like effector nucleases (TALENs) to the widespread adoption of CRISPR‐Cas systems. First‐generation editors catalyzed genome engineering by introducing targeted double‐strand breaks (DSBs ...
Li‐Kuang Tsai, Youcai Xiong, Dongqi Liu, Dongshan Yang, Jifeng Zhang, Jie Xu, Renzhi Han, Y. Eugene Chen   +7 more
wiley   +1 more source

Distinguishing lung cancer from atypical tuberculosis: Deep transfer learning and imaging omics features

Journal of Intelligent Medicine, EarlyView.
The 3D‐ResNet model demonstrates superior discriminative power in differentiating lung cancer from atypical tuberculosis by leveraging deep omics features derived from volumetric lung cancer imaging, outperforming conventional clinical and radiomic analyses.
Yi Wu, Siyi Li, Zhiping Long, Yanjie Jia, Yue Yu, Bing Pei, Heli Yuan, Yuhua Hao, Zhiyun Jiang, Lei Cao, Kezheng Wang, Fan Wang   +11 more
wiley   +1 more source

BCGiosis as a presenting feature of a child with chronic granulomatous disease

Brazilian Journal of Infectious Diseases
Bacillus Calmette Guerin (BCG) vaccine, which is administered to all newborns in some regions, could lead to serious complication ranging from local disease (known as BCGitis) to disseminated disease (BCGosis) in a group of patients with primary ...
Zahra Movahedi, Sayna Norouzi, Setareh Mamishi, Nima Rezaei   +3 more
doaj   +1 more source

Severe allergic reaction to ustekinumab reinitiation in a pediatric patient with Crohn's disease: A case report

JPGN Reports, EarlyView.
Abstract Ustekinumab (UST) is a monoclonal antibody used in the management of moderate to severe inflammatory bowel disease. While generally well‐tolerated, serious adverse reactions, including hypersensitivity and anaphylaxis, have been documented, specifical following the initial intravenous (IV) dose.
Kennedy Sparling, Shauna Schroeder, Brad Pasternak   +2 more
wiley   +1 more source

Gastric antral stricture in a patient with chronic granulomatous disease

The Turkish Journal of Pediatrics, 1999
Chronic granulomatous disease (CGD) is a rare disorder of phagocytic cell oxidative metabolism. Patients have recurrent infections with catalase-positive organisms and granulomatous lesions throughout the body. Gastric antrum can be an occult site
A Metin, O Sanal, I Tezcan, F Ersoy, A I Berkel   +4 more
doaj  

Causes of mortality and characterisation of Mycobacteriosis in adult New Zealand sea lions (Phocarctos Hookeri) at Enderby Island : a thesis presented in partial fulfilment of the requirements for the degree of Master of Veterinary Science in Wildlife Health at Massey University, Manawatū, Palmerston North, New Zealand [PDF]

, 2017
The New Zealand sea lion (Phocarctos hookeri) is classified as endangered and “Nationally Critical” due to a declining population and restricted population range. There have been recent bacterial epizootic events at the breeding colonies of this species,
Lenting, Baukje Mirjam
core  

Gastric antral vascular ectasia: A rare etiology of gastrointestinal bleeding in children

JPGN Reports, EarlyView.
Abstract Gastrointestinal bleeding is relatively common in children. While most patients present with mild bleeding, gastric antral vascular ectasia (GAVE) is a rare but potentially life‐threatening cause. GAVE is typically associated with chronic conditions and more common in adults.
Omar Alharbi, Sindhura Kasturi, George Yanni, Blake Rosenthal   +3 more
wiley   +1 more source

Observational study of metastatic vulvar Crohn's disease in the pediatric population

JPGN Reports, EarlyView.
Abstract Objective Metastatic vulvar Crohn's disease (MVCD) is a rare cutaneous manifestation of Crohn's disease (CD), especially in pediatric patients. The objective of this study is to assess presentation, diagnosis, and treatment for pediatric MVCD in the largest cohort reported. Methods This is a retrospective review of pediatric patients with MVCD
Deborah Winograd, Afua Addo, Taryn Wassmer, Jennifer Hellmann, Daniel Mallon, Kalyani Marathe, Christine Pennesi   +6 more
wiley   +1 more source

Multiparametric Ultrasound Findings of Testicular Sarcoidosis

Journal of Ultrasound in Medicine, EarlyView.
Objectives To characterize the multiparametric ultrasound (MPUS) features of testicular sarcoidosis, incorporating greyscale, color Doppler ultrasound (CDUS), contrast‐enhanced ultrasound (CEUS), and strain elastography (SE), and to assess their collective diagnostic value.
Huahui Liu, Razan Abudalo, Ghali Salahia, Gibran T. Yusuf, Dean Y. Huang, Paul S. Sidhu   +5 more
wiley   +1 more source