Clinical Features and Therapeutic Outcomes in Pyoderma Gangrenosum: A Prospective Cohort Study
JEADV Clinical Practice, EarlyView.ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis highly associated with systemic comorbidities. Accurate diagnosis and treatment remain challenging due to its rarity and clinical mimickers. Objectives To evaluate demographic, clinical features and treatment outcomes in patients referred with suspected PG at a tertiary ...
David Croitoru +13 more
wiley +1 more source
Assessing the Effect of Adalimumab in Granuloma Annulare: A Case Series and Literature Review
JEADV Clinical Practice, EarlyView.ABSTRACT Granuloma annulare (GA) is a benign granulomatous skin disorder for which standardized treatment guidelines are lacking due to limited evidence. Adalimumab, a TNF‐α inhibitor, shows promise as a therapeutic option due to its potential to disrupt GA granulomas.
Adriana Caixinha Valorenzos +2 more
wiley +1 more source
Intact natural killer activity in chronic granulomatous disease: evidence against an oxygen-dependent cytotoxic mechanism. [PDF]
, 1984 A el-Hag, Robert A. Clark
openalex +1 more source
Immunosuppression and Surgery‐Free Interval in Granulomatosis With Polyangiitis Airway Stenosis
The Laryngoscope, EarlyView.Subglottic and tracheal stenosis are severe manifestations of granulomatosis with polyangiitis (GPA) that often require both endoscopic intervention and systemic immunosuppression. Rituximab may help stabilize GPA‐related airway disease by prolonging the interval between endoscopic procedures and delaying relapse.
Sydney J. Torres +6 more
wiley +1 more source
Genetic Analysis of 10 Unrelated Korean Families with p22-phox-deficient Chronic Granulomatous Disease: An Unusually Identical Mutation of the CYBA Gene on Jeju Island, Korea [PDF]
, 2009 Youngmee Kim +6 more
openalex +1 more source
IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak +7 more
wiley +1 more source
Chronic lip swelling as the sole presentation of Crohn's disease: three case reports
The Turkish Journal of Pediatrics, 2015 Chronic lip swelling may be a clinical sign of a systemic disease, such as Crohn's. We report two cases of children in Greece where the chronic lip swelling was not only the initial, but the sole clinical symptom of Crohn's, and another case with ...
Smaragdi Fessatou +6 more
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