Results 21 to 30 of about 91,225 (237)

In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsy specimens of intestinal tuberculosis and Crohn disease [PDF]

open access: yes, 2008
Tuberculosis and Crohn disease are granulomatous disorders affecting the intestinal tract with similar clinical manifestations and pathologic features.
Donoghue, HD   +3 more
core   +1 more source

Topical tacrolimus 0.1% ointment for treatment of cutaneous Crohn's Disease [PDF]

open access: yes, 2013
Peer reviewedPublisher ...
El-Omar, Emad   +4 more
core   +2 more sources

Differences in reactivation of tuberculosis induced from anti-tnf treatments are based on bioavailability in granulomatous tissue [PDF]

open access: yes, 2007
The immune response to Mycobacterium tuberculosis (Mtb) infection is complex. Experimental evidence has revealed that tumor necrosis factor (TNF) plays a major role in host defense against Mtb in both active and latent phases of infection.
Denise E Kirschner   +7 more
core   +3 more sources

Recent advances in chronic granulomatous disease

open access: yesGenes and Diseases, 2020
Chronic granulomatous disease (CGD) is an inherited defect of phagocyte function due to defective NADPH oxidase. Patients with CGD are not able to effectively clear the infections because of the defect in the phagocyte production of oxygen free radicals ...
Gummadi Anjani   +6 more
doaj   +1 more source

BCGiosis as a presenting feature of a child with chronic granulomatous disease

open access: yesBrazilian Journal of Infectious Diseases, 2011
Bacillus Calmette Guerin (BCG) vaccine, which is administered to all newborns in some regions, could lead to serious complication ranging from local disease (known as BCGitis) to disseminated disease (BCGosis) in a group of patients with primary ...
Zahra Movahedi   +3 more
doaj   +1 more source

Fatal Meningitis in Patient with X-Linked Chronic Granulomatous Disease Caused by Virulent Granulibacter bethesdensis

open access: yesEmerging Infectious Diseases, 2019
Granulibacter bethesdensis is a pathogen reported to cause recurrent lymphadenitis exclusively in persons with chronic granulomatous disease. We report a case of fatal meningitis caused by a highly virulent G.
Mafalda Rebelo   +7 more
doaj   +1 more source

New Perspectives on the Immunopathogenesis and Treatment of Uveitis Associated With Vogt-Koyanagi-Harada Disease

open access: yesFrontiers in Medicine, 2021
Uveitis associated with Vogt-Koyanagi-Harada (VKH) disease is a bilateral, chronic, granulomatous autoimmune disease associated with vitiligo, poliosis, alopecia, and meningeal and auditory manifestations.
Ahmed M. Abu El-Asrar   +4 more
doaj   +1 more source

Lacrimal gland tumors in Turkey: types, frequency, and outcomes. [PDF]

open access: yes, 2018
AIM: To evaluate the clinical, radiological, and treatment features of lacrimal gland tumors. METHODS: Retrospective review of 99 eyes of 92 patients with lacrimal gland tumors diagnosed and managed in a single institution between January 1999 and March ...
Erden, Esra   +3 more
core   +2 more sources

Chronic granulomatous disease: why an inflammatory disease?

open access: yesBrazilian Journal of Medical and Biological Research, 2014
Chronic granulomatous disease is a primary immunodeficiency caused by mutations in the genes encoding subunits of the phagocytic NADPH oxidase system. Patients can present with severe, recurrent infections and noninfectious conditions.
P. Roxo-Junior, H.M.L. Simão
doaj   +1 more source

Cellular Therapies in Chronic Granulomatous Disease

open access: yesFrontiers in Pediatrics, 2020
Allogeneic hematopoietic stem cell transplantation (HSCT) has become the main curative treatment in patients with chronic granulomatous disease (CGD). CGD is caused by inherited defects of the phagolysomal NADPH-oxidase, leading to a lifelong propensity ...
Tayfun Güngör, Robert Chiesa
doaj   +1 more source

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