Results 21 to 30 of about 7,512,016 (281)

Disseminated Aspergillosis as the Herald Manifestation of Chronic Granulomatous Disease in an Adult Patient [PDF]

Iranian Journal of Allergy, Asthma and Immunology, 2014
Chronic granulomatous disease is an inherited defect in intracellular killing of ingested microorganisms characterized by recurrent life threatening bacterial and fungal infections including invasive aspergillosis in early childhood.
Ilad Alavi Darazam, Hossein Akhavan Zanjani, Davood Sanaee, Payam Tabarsi, Mostafa Alavi Moghaddam, Davood Mansouri   +5 more
doaj   +1 more source

Chronic Granulomatous Disease with Disseminated Trichosporonosis : A Case Report [PDF]

Siriraj Medical Journal, 2020
A case of a two year and three month old Thai boy with a history of recurrent bacterial infections since aged 2 months. A definite absence of superoxide activity in the patient' s granulocytes detected by nitroblue tetrazolium test indicated the ...
Samonmars Kanngurn, Paisal Parichatikanond, Visanu Pootong, Pakit Vichyanond   +3 more
doaj   +1 more source

Chronic granulomatous disease [PDF]

British Medical Bulletin, 2016
Chronic granulomatous disease is a clinical condition that stems from inactivating mutations in NOX2 and its auxiliary proteins. Together, these proteins form the phagocyte NADPH oxidase enzyme that generates superoxide. Superoxide (O2ċ-) and its reduced product hydrogen peroxide (H2O2) give rise to several additional reactive oxygen species (ROS ...
Amit, Rawat, Sagar, Bhattad, Surjit, Singh   +2 more
openaire   +6 more sources

Second Report of Chronic Granulomatous Disease in Jordan: Clinical and Genetic Description of 31 Patients From 21 Different Families, Including Families From Lybia and Iraq

Frontiers in Immunology, 2021
Chronic granulomatous Disease (CGD) is a rare innate immunodeficiency disorder caused by mutations in one of the six genes (CYBA, CYBB, NCF1, NCF2, NCF4, and CYBC1/EROS) encoding the superoxide-producing nicotinamide adenine dinucleotide phosphate (NADPH)
Faris Ghalib Bakri, Faris Ghalib Bakri, Michelle Mollin, Sylvain Beaumel, Bénédicte Vigne, Nathalie Roux-Buisson, Nathalie Roux-Buisson, Adel Mohammed Al-Wahadneh, Raed Mohammed Alzyoud, Wail Ahmad Hayajneh, Ammar Khaled Daoud, Mohammed Elian Abu Shukair, Mansour Fuad Karadshe, Mahmoud Mohammad Sarhan, Jamal Ahmad Wadi Al-Ramahi, Julien Fauré, Julien Fauré, John Rendu, John Rendu, Marie Jose Stasia, Marie Jose Stasia   +20 more
doaj   +1 more source

Sarcoidosis in coexistence with chronic granulomatous disease [PDF]

, 2021
Granulomas formations are present in many lung diseases. Coexistence of one or more of these diseases is very rare. Diagnostics of such cases always poses a challenge.
Śniady, Anna; 3rd Lung Diseases and Oncology Department, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland, Burakowska, Barbara; Radiology Department, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland, Martusewicz-Boros, Magdalena; 3rd Lung Diseases and Oncology Department, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland, Boros, Piotr; Lung Pathophysiology Department, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland, Magdalena Martusewicz-Boros, Anna Śniady, Piotr Boros, Barbara Burakowska   +7 more
core   +2 more sources

A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?

Dermatology Reports, 2022
We report the case of a patient with chronic granulomatous disease and acne treated with isotretinoin, who developed a diffuse staphylococcal skin infection during the therapy. Chronic granulomatous disease is a rare genetic disorder characterized by an
Marco Brusasco, Claudio Feliciani, Maria Beatrice de Felici del Giudice   +2 more
doaj   +1 more source

Chronic Granulomatous Disease Presenting with Salmonella Brain Abscesses. [PDF]

, 2014
Chronic granulomatous disease is a rare primary immunodeficiency caused by phagocytic cell defect. We describe the case of 43-month-old boy with chronic granulomatous disease presenting with Salmonella spp brain abscesses, together with a review of ...
Finocchi A, Claps A, Serafinelli J, Salfa I, Longo D, Di Matteo G, Aiuti A, Rossi P, ROSSI, PAOLO, Claps A, Rossi P., DI MATTEO, GIGLIOLA, Di Matteo G, Finocchi A, AIUTI, ALESSANDRO, Salfa I, Longo D, FINOCCHI, ANDREA, Serafinelli J, AIUTI , ALESSANDRO   +12 more
core   +2 more sources

Chronic granulomatous disease [PDF]

The British Journal of Radiology, 1970
Abstract Chronic granulomatous disease is a hereditable disorder in which polymorphs show diminished capacity for killing bacteria. Defective bactericidal activity results in protracted infection. The lesions of chronic granulomatous disease may affect all systems of the body.
J, Sutcliffe, A R, Chrispin
openaire   +4 more sources

Etiology of granulomatous inflammation: A retrospective study of 174 children in a tertiary care center

Asian Pacific Journal of Tropical Medicine, 2022
Objective: To investigate granulomatous inflammation etiology based on clinical history and ancillary tests. Methods: Children aged
Ummühan Cay, Derya Alabaz, Özlem Özgür Gündeşlioğlu, Aysun Hatice Uguz, Hande Yanar   +4 more
doaj   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

Hepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane   +19 more
wiley   +1 more source