Results 81 to 90 of about 5,872,061 (285)

Dedifferentiation in endometrial cancer is associated with HLA‐I silencing that may be restored by IFN‐γ

The Journal of Pathology, EarlyView.
Abstract Dedifferentiated endometrial carcinoma occurs when a prognostically favorable low‐grade endometrial carcinoma transforms into a highly aggressive undifferentiated carcinoma following genomic inactivation of core SWItch/Sucrose Non‐Fermentable (SWI/SNF) complex protein(s).
Antonio De Leo, Madison Wickenberg, Marco Grillini, Camelia Alexandra Coadǎ, Pooja Praveen Kumar, Annie Tong, James Key, Hannah Kim, Felix Kommoss, Mark Carey, Yangxin Fu, Claudio Ceccarelli, Giovanni Tallini, Paul LaPointe, Martin Köbel, Cheng‐Han Lee   +15 more
wiley   +1 more source

A Case Diagnosed with Chronic Granulomatous Disease Presenting with Dactylitis

Bagcilar Medical Bulletin
Chronic granulomatous disease is a rare primary immunodeficiency seen in 1/70,000-1/200,000 births. It is a monogenetic disease caused by defects in the nicotinamideadenine-dinucleotide-phosphate oxidase enzyme complex.
Selami Ulaş, Işılay Turan, Mehmet Halil Çeliksoy, Gözde Kurşun, Sezin Naiboğlu, Çiğdem Aydoğmuş   +5 more
doaj   +1 more source

Chronic Granulomatous Disease with Disseminated Trichosporonosis : A Case Report

Siriraj Medical Journal, 2020
A case of a two year and three month old Thai boy with a history of recurrent bacterial infections since aged 2 months. A definite absence of superoxide activity in the patient' s granulocytes detected by nitroblue tetrazolium test indicated the ...
Samonmars Kanngurn, Paisal Parichatikanond, Visanu Pootong, Pakit Vichyanond   +3 more
doaj  

Granulomatous Mastitis Concurrence with Breast Cancer

European Journal of Breast Health, 2018
Idiopathic Granulomatous Mastitis (IGM) is a rare, chronic, non-malignant and non-life-threatening breast disease. IGM may mimic carcinoma of the breast. This case report is about concurrence of chronic granulomatous mastitis with breast cancer.
Hasan Çalış, Asuman Kilitçi
doaj   +1 more source

Enlarging Fingertip Nodule Mimicking a Pyogenic Granuloma in a Man in his 60's

JEADV Clinical Practice, EarlyView.
Avery H. Seward, Jocelyn H. LaRocque, Stephen M. Hughes   +2 more
wiley   +1 more source

Immunomodulatory Properties of Withania somnifera: Regulation of Innate Immune Cells and Clinical Implications

Phytotherapy Research, EarlyView.
ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta, Sonalika Gupta, Gagandeep Kaur, Partha Sarathi Mondal, Milirani Das, Anagha Ranade, Alok Kumar Srivastava, Sachin Kumar, Manoj Kumar Barthwal, Madhu Dikshit   +9 more
wiley   +1 more source

Role of clinical questionnaires in optimizing everyday care of chronic obstructive pulmonary disease. [PDF]

, 2011
: Chronic obstructive pulmonary disease (COPD) is a leading cause of disability in all its stages, and death in patients with moderate or severe obstruction.
van der Molen, T, Jones PW, Jones, P., van der Molen, T., Price, D, Price, David, Jones, PW, van der Molen, Thys, Jones, Paul W., Price D, van der Molen T, Price, D.   +11 more
core   +2 more sources

Infection risk in rheumatoid arthritis patients treated with biologic and targeted therapies

Rheumatology &Autoimmunity, EarlyView.
In this context, infections associated with each biologic and targeted drug are summarized to inform the stratification of RA patients, including the characteristics of the susceptible patients and their concomitant therapy. We aim to provide a benefit‐risk analysis for clinical decision, and vital indications for the prevention of highly correlated ...
Lujing Wang, Jieshi Lin, Jie Qian
wiley   +1 more source

Chronic Granulomatous Disease; Experience of a Rare Primary Immunodeficiency from a Tertiary Care Center in Pakistan

Pakistan Armed Forces Medical Journal
Objective: To determine the clinical parameters, consanguinity of parents, previous family history of primary immunodeficiency (PID) and Neutrophil oxidative index (NOI) of Dihydrorhodamine (DHR) assay in chronic granulomatous disease (CGD).
Muhammad Hussain, Hamid Nawaz Tipu, Dawood Ahmad, Mustajab Alam, Yumna Ijaz, Ehsan Qadir   +5 more
doaj   +1 more source

Driving Drugs Deeper: Force‐Driven Microneedle Systems for Active Therapy and Their Road Towards Clinical Implementation

Small, EarlyView.
Force‐driven microneedles are presented as active therapeutic microdevices that overcome the diffusion limits of conventional patches. By integrating gas generation, magnetic actuation, cavitation, or iontophoresis, these systems drive payloads deeper into tissue, enabling faster, more controlled delivery and highlighting key design principles and ...
Majed Amini, Phoebe Li, Hamed Shahsavan, Mahla Poudineh   +3 more
wiley   +1 more source