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Chronic heart failure (CHF) is a major healthcare problem. CHF is both physically and emotionally disabling and has a major impact on quality of life. Moreover, CHF has a long-term prognosis comparable to or worse than most common malignancies. 1 It is a frequent reason for unplanned hospital admissions, and has a major impact on healthcare resources ...
Mark T. Kearney, Helen Williams
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It is widely recognized that hypertension is one of the major risk factor for disease severity and mortality in patients with coronavirus disease 2019 (COVID‐19). However, type 2 diabetes mellitus (T2DM) and hypertension are frequent comorbid conditions,
Yuhui Sun+7 more
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Objective: Although guidelines have recommended standardized drug treatment for heart failure (HF), there are still many challenges in making the correct clinical decisions due to the complicated clinical situations of HF patients.
Yongyi Bai+12 more
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Background and Aims: Previous work has shown the association between blood-based methylation of coagulation factor II receptor-like 3 gene (F2RL3) and cardiovascular mortality in Caucasians.
Xiaojing Zhao+10 more
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What can we learn from SOCRATES: more questions than answers? [PDF]
This editorial refers to ‘Vericiguat in patients with worsening chronic heart failure and preserved ejection fraction: results of the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED EF (SOCRATES-PRESERVED) Study’, by B ...
Cleland, John G.F., Mueller, Christian
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BackgroundCoronary artery disease (CAD) is a progressive disease of the blood vessels supplying the heart, which leads to coronary artery stenosis or obstruction and is life-threatening.
Xiao Wang+28 more
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Physiological monitoring in the complex multimorbid heart failure patient - Conclusions. [PDF]
Comorbidities are increasingly recognized as crucial components of the heart failure syndrome. Main specific challenges are polypharmacy, poor adherence to treatments, psychological aspects, and the need of monitoring after discharge.
Böhm, M+4 more
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Iron deficiency in chronic heart failure: case-based practical guidance [PDF]
In patients with chronic heart failure, iron deficiency, even in the absence of anaemia, can aggravate the underlying disease and have a negative impact on clinical outcomes and quality of life.
Comín Colet, Josep+3 more
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Renal dysfunction, which is associated with bad clinical outcomes, is one of the most common complications of heart failure (HF). Timely prediction of renal dysfunction can help medical staffs intervene early to avoid catastrophic consequences.
Binhua Wang+9 more
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Risk factors for heart failure in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methyl [PDF]
Background: A phase 3 randomized clinical trial was designed to test whether bardoxolone methyl, a nuclear factor erythroid-2–related factor 2 (Nrf2) activator, slows progression to end-stage renal disease in patients with stage 4 chronic kidney disease
Bakris, George L.+10 more
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