Results 31 to 40 of about 607,319 (267)

Creation of registers as one of the mechanisms for improving medical care for patients with chronic heart failure. Problem state

Терапевтический архив, 2023
The annual mortality of patients with clinically pronounced symptoms of chronic heart failure in the Russian Federation reaches 2629%, i.e., from 880 to 986 thousand patients with heart failure die in the country in one year, which is comparable to the ...
Oleg M. Reitblat, Anna A. Airapetian, Natalia V. Lazareva, Evgeny M. Mezhonov, Evgeny V. Sorokin, Iuliia Sh. Prints, Zoya N. Blankova, Olga N. Svirida, Fail T. Ageev, Igor V. Zhirov, Sergey N. Tereshchenko, Sergey A. Boytsov   +11 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Chronic heart failure

South African Family Practice, 2015
Heart failure is a global problem. It is estimated that approximately 38 million people worldwide experience heart failure, and this number is growing because of the ageing of nations’ populations, but also because patients are rescued from death during ...
J. A. Ker
doaj   +1 more source

Cardiorenal relationships in patients with chronic heart failure with preserved ejection fraction

Лечащий Врач, 2023
The combination of heart and kidney diseases caused by chronic heart failure and aggravated by kidney damage, called cardiorenal syndrome, is increasingly recognized as a critical pathological unit, leading to a worsening of the prognosis in patients ...
Yu. N. Panina, V. I. Vishnevsky
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Oridonin as a novel KDM5C inhibitor alleviates clonal hematopoiesis-induced cardiac aging via H3K4me3-dependent SASP suppression

Acta Pharmaceutica Sinica B
TET2-mediated clonal hematopoiesis of indeterminate potential (CHIP) is a known cardiovascular risk factor, but its role in cardiac aging and potential for pharmacological intervention remain unclear.
Xingling Chen, Qiangqiang Zhao, Linhuang Chen, Shengrong Lin, Bin Mai, Xingling He, Xiaojiao Zhang, Jiahui Chen, Sijing Li, Ziru Li, Hua Zhang, Yuehui Zhou, Xiaofang Li, Huili Liao, Taochun Ye, Shuning Sun, Zhongqi Yang, Shihao Ni, Lu Lu   +18 more
doaj   +1 more source

Signaling cascades in the failing heart and emerging therapeutic strategies

Signal Transduction and Targeted Therapy, 2022
Chronic heart failure is the end stage of cardiac diseases. With a high prevalence and a high mortality rate worldwide, chronic heart failure is one of the heaviest health-related burdens.
Xin He, Tailai Du, Tianxin Long, Xinxue Liao, Yugang Dong, Zhan-Peng Huang   +5 more
doaj   +1 more source

Periodontitis in Chronic Heart Failure [PDF]

Texas Heart Institute Journal, 2016
Periodontal disease has been associated with an increased risk of cardiovascular events. The purpose of our study was to investigate whether a correlation between periodontitis and chronic heart failure exists, as well as the nature of the underlying cause.
Fröhlich, Hanna, Herrmann, Kristina, Franke, Jennifer, Karimi, Alamara, Täger, Tobias, Cebola, Rita, Katus, Hugo A, Zugck, Christian, Frankenstein, Lutz   +8 more
openaire   +3 more sources