Results 21 to 30 of about 1,183,948 (211)

Construction of a Non-Mutually Exclusive Decision Tree for Medication Recommendation of Chronic Heart Failure

Frontiers in Pharmacology, 2022
Objective: Although guidelines have recommended standardized drug treatment for heart failure (HF), there are still many challenges in making the correct clinical decisions due to the complicated clinical situations of HF patients.
Yongyi Bai, Yongyi Bai, Haishen Yao, Xuehan Jiang, Suyan Bian, Suyan Bian, Jinghui Zhou, Xingzhi Sun, Gang Hu, Lan Sun, Guotong Xie, Kunlun He, Kunlun He   +12 more
doaj   +1 more source

Renal effects and associated outcomes during angiotensin-neprilysin inhibition in heart failure [PDF]

, 2018
Objectives: The purpose of this study was to evaluate the renal effects of sacubitril/valsartan in patients with heart failure and reduced ejection fraction.
Claggett, Brian, Damman, Kevin, Desai, Akshay S., Gori, Mauro, Jhund, Pardeep S., Lefkowitz, Martin P., McMurray, John J.V., Packer, Milton, Prescott, Margaret F., Rouleau, Jean L., Senni, Michele, Shi, Victor C., Solomon, Scott D., Swedberg, Karl, Zile, Michael R.   +14 more
core   +9 more sources

Metabolic and cardiac adaptation to chronic pharmacologic blockade of facilitative glucose transport in murine dilated cardiomyopathy and myocardial ischemia [PDF]

, 2018
GLUT transgenic and knockout mice have provided valuable insight into the role of facilitative glucose transporters (GLUTs) in cardiovascular and metabolic disease, but compensatory physiological changes can hinder interpretation of these models.
Heitmeier, Monique R., Hresko, Richard C., Hruz, Paul W., Jay, Patrick Y., Kovacs, Attila, Payne, Maria A., Weinheimer, Carla   +6 more
core   +2 more sources

Activity Theory Analysis of Heart Failure Self-Care [PDF]

, 2017
The management of chronic health conditions such as heart failure is a complex process emerging from the activity of a network of individuals and artifacts.
Cornet, Victor, Holden, Richard J., Voida, Stephen   +2 more
core   +1 more source

Inhibiting Receptor of Advanced Glycation End Products Attenuates Pressure Overload-Induced Cardiac Dysfunction by Preventing Excessive Autophagy

Frontiers in Physiology, 2018
The receptor for advanced glycation end products (RAGE) is involved in heart failure (HF) by mediating diverse pathologic processes, including the promotion of inflammation and autophagy.
Wenbin Gao, Wenbin Gao, Wenbin Gao, Zheng Zhou, Zheng Zhou, Zheng Zhou, Birong Liang, Birong Liang, Birong Liang, Yusheng Huang, Yusheng Huang, Yusheng Huang, Zhongqi Yang, Zhongqi Yang, Zhongqi Yang, Yang Chen, Yang Chen, Lu Zhang, Lu Zhang, Lu Zhang, Cui Yan, Cui Yan, Cui Yan, Jiajia Wang, Jiajia Wang, Jiajia Wang, Lu Lu, Lu Lu, Lu Lu, Zhaorui Wen, Zhaorui Wen, Shaoxiang Xian, Shaoxiang Xian, Shaoxiang Xian, Lingjun Wang, Lingjun Wang, Lingjun Wang   +36 more
doaj   +1 more source

Impact of an interatrial shunt device on survival and heart failure hospitalization in patients with preserved ejection fraction [PDF]

, 2019
Aims: Impaired left ventricular diastolic function leading to elevated left atrial pressures, particularly during exertion, is a key driver of symptoms and outcomes in heart failure with preserved ejection fraction (HFpEF). Insertion of an interatrial
Aytug, H, Bergmann, MW, Doughty, RN, Gustafsson, F, Hasenfuβ, G, Hausleiter, J, Hayward, C, Jondeau, G, Kaye, DM, Kolodziej, A, Lang, I, Malek, F, McKenzie, S, Penicka, M, Petrie, MC, Ponikowski, P, Post, M, Raake, P, REDUCE LAP-HF study investigators,, Rosenberg, M, Spelman, T, Trochu, J-N, Westenfeld, R   +22 more
core   +2 more sources

Novel perspectives in redox biology and pathophysiology of failing myocytes: modulation of the intramyocardial redox milieu for therapeutic interventions - A review article from the Working Group of Cardiac Cell Biology, Italian Society of Cardiology [PDF]

, 2016
The prevalence of heart failure (HF) is still increasing worldwide, with enormous human, social, and economic costs, in spite of huge efforts in understanding pathogeneticmechanisms and in developing effective therapies that have transformed this ...
Angelini, Annalisa, Arcaro, Alessia, Chimenti, Cristina, Crotti, Lia, Giordano, Carla, Mancardi, Daniele, Pirozzi, Flora, Tocchetti, Carlo G., Torella, Daniele   +8 more
core   +9 more sources

Novel Targets in a High-Altitude Pulmonary Hypertension Rat Model Based on RNA-seq and Proteomics

Frontiers in Medicine, 2021
High-altitude pulmonary hypertension (HAPH) is a complication arising from an inability to acclimatize to high altitude and is associated with high morbidity and mortality.
Xiang Xu, Hanlu Li, Qingxia Wei, Xin Li, Xin Li, Yanying Shen, Ge Guo, Yibing Chen, Kunlun He, Kunlun He, Chunlei Liu, Chunlei Liu   +11 more
doaj   +1 more source

‘Hearts and minds’: association, causation and implication of cognitive impairment in heart failure [PDF]

, 2015
The clinical syndrome of heart failure is one of the leading causes of hospitalisation and mortality in older adults. An association between cognitive impairment and heart failure is well described but our understanding of the relationship between the ...
Cannon, Jane A., McMurray, John J.V., Quinn, Terry J.   +2 more
core   +4 more sources

Chronic heart failure and micronutrients

Journal of the American College of Cardiology, 2001
Heart failure (HF) is associated with weight loss, and cachexia is a well-recognized complication. Patients have an increased risk of osteoporosis and lose muscle bulk early in the course of the disease. Basal metabolic rate is increased in HF, but general malnutrition may play a part in the development of cachexia, particularly in an elderly ...
Witte, Klaus K.A., Clark, Andrew L., Cleland, John G.F.   +2 more
openaire   +2 more sources