Novel Targets in a High-Altitude Pulmonary Hypertension Rat Model Based on RNA-seq and Proteomics
High-altitude pulmonary hypertension (HAPH) is a complication arising from an inability to acclimatize to high altitude and is associated with high morbidity and mortality.
Xiang Xu+11 more
doaj +1 more source
Duration of heart failure and the risk of atrial fibrillation: different mechanisms at different times? [PDF]
Chronic heart failure increases the risk of atrial fibrillation (AF), with the prevalence of AF paralleling the severity of heart failure.1 Factors that underlie this increased susceptibility to AF may include electrical, structural, and neurohumoral ...
A. C. Rankin+10 more
core +1 more source
Chronic heart failure and micronutrients
Heart failure (HF) is associated with weight loss, and cachexia is a well-recognized complication. Patients have an increased risk of osteoporosis and lose muscle bulk early in the course of the disease. Basal metabolic rate is increased in HF, but general malnutrition may play a part in the development of cachexia, particularly in an elderly ...
Klaus K. Witte+2 more
openaire +3 more sources
The receptor for advanced glycation end products (RAGE) is involved in heart failure (HF) by mediating diverse pathologic processes, including the promotion of inflammation and autophagy.
Wenbin Gao+36 more
doaj +1 more source
Health-related quality of life in elderly patients hospitalized with chronic heart failure [PDF]
Background: Chronic heart failure is a very common condition in the elderly, characterized not only by high mortality rates, but also by a strong impact on health-related quality of life (HRQOL).
Bojovic, Ognjen+11 more
core +4 more sources
Impact of an interatrial shunt device on survival and heart failure hospitalization in patients with preserved ejection fraction [PDF]
Aims: Impaired left ventricular diastolic function leading to elevated left atrial pressures, particularly during exertion, is a key driver of symptoms and outcomes in heart failure with preserved ejection fraction (HFpEF). Insertion of an interatrial
Aytug, H+22 more
core +2 more sources
Pharmacotherapy for chronic heart failure
Heart failure is a chronic and progressive disorder which results due to inability of the heart to pump adequate blood to meet up the metabolic demands of the body. Detecting patients with heart failure could be simple but rather complex of clinical decisions as presentation could be classical or non-specific with minimal symptoms and orsigns ...
Jalal-Eddeen Abubakar Saleh+2 more
openaire +4 more sources
Phosphoproteomic and proteomic profiling in post-infarction chronic heart failure
Background: Post-infarction chronic heart failure is the most common type of heart failure. Patients with chronic heart failure show elevated morbidity and mortality with limited evidence-based therapies.
Jiayue Wang+7 more
doaj +1 more source
‘Hearts and minds’: association, causation and implication of cognitive impairment in heart failure [PDF]
The clinical syndrome of heart failure is one of the leading causes of hospitalisation and mortality in older adults. An association between cognitive impairment and heart failure is well described but our understanding of the relationship between the ...
Cannon, Jane A.+2 more
core +4 more sources
Randomised controlled trial of specialist nurse intervention in heart failure [PDF]
<p>Objectives. To determine whether specialist nurse intervention improves outcome in patients with chronic heart failure.</p> <p>Design. Randomised controlled trial.</p> <p>Setting.
Blue, L.+11 more
core +2 more sources