Results 41 to 50 of about 616,613 (359)

The Natural History of Hepatitis C Virus Infection and Disease in the Era of Curative Therapy with Direct-Acting Antivirals

Viruses
The availability of highly effective direct-acting antivirals (DAAs) that cure individuals infected with HCV has changed completely the natural history of HCV infection and chronic hepatitis C.
Maurizia Rossana Brunetto, Ferruccio Bonino   +1 more
doaj   +1 more source

КЛИНИКО-ЛАБОРАТОРНАЯ ХАРАКТЕРИСТИКА ХРОНИЧЕСКИХ ГЕПАТИТОВ И ЦИРРОЗОВ ПЕЧЕНИ РАЗЛИЧНОЙ ЭТИОЛОГИИ

Архивъ внутренней медицины, 2015
The review of literature discusses the clinical and biochemical changes in patients with chronic hepatitis C, chronic hepatitis of alcoholic etiology, chronic hepatitis combined genesis (HCV + alcohol) and cirrhosis in the outcome of hepatitis, liver ...
А. Р. Билалова, В. В. Макашова   +1 more
doaj   +1 more source

Cross-sectional study of changes in physical activity behavior during the COVID-19 pandemic among US adults

International Journal of Behavioral Nutrition and Physical Activity, 2021
Background Physical activity (PA) provides numerous health benefits relevant to the COVID-19 pandemic. However, concerns exist that PA levels may have decreased during the pandemic thus exacerbating health disparities.
Kathleen B. Watson, Geoffrey P. Whitfield, George Huntzicker, John D. Omura, Emily Ussery, Tiffany J. Chen, Robyn Neblett Fanfair   +6 more
doaj   +1 more source

The prevalence of hepatitis B surface antigen and anti-hepatitis B core antibody in Iran: A population-based study [PDF]

, 2009
Background: Hepatitis B virus infection is a very common cause of chronic liver disease worldwide. It is estimated that 3 of Iranians are chronically infected with hepatitis B virus.
Abolghasemi, H., Amini-Kafiabad, S., Assari, S., Hosseini, M.R., Jamali, J., Maghsudlu, M., Malekzadeh, R., Merat, S., Nouraie, M., Pourshams, A., Radmard, A.R., Rezvan, H., Zaer-Rezaii, H., Zeid-Abadi-Nejhad, M.   +13 more
core  

Icteric flare of chronic hepatitis B in a 95-year old patient [PDF]

, 2003
A 95-year old gentleman developed fatal icteric flare of chronic hepatitis B despite lamivudine treatment. This article highlights the atypical presentations of chronic hepatitis B in elderly patient and the need to consider this possibility for acute ...
Chan, HLY, Leung, WK, Wong, WS
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

An extracellular humanized IFNAR immunocompetent mouse model for analyses of human interferon alpha and subtypes

Emerging Microbes and Infections
Type I interferons (IFN-Is) have key roles in immune defense and treatments for various diseases, including chronic hepatitis B virus (HBV) infection.
Yumeng Li, Asha Ashuo, Menghan Hao, Yaming Li, Jianyu Ye, Jiangxia Liu, Ting Hua, Zhong Fang, Jianhua Li, Zhenghong Yuan, Jieliang Chen   +10 more
doaj   +1 more source

Costs of Treatment, Follow-Up, and Complications of Chronic Hepatitis B and Hepatitis C Infections

Balkan Medical Journal, 2013
Background: Few studies have addressed the indirect costs of chronic hepatitis B and C, and none has assessed the real costs of these conditions, including indirect costs caused by loss of work, in Turkey. Aims: This study therefore analysed the costs of
Fatma Banu Karahasanoğlu, Ali Asan, Suzan Sacar, Hüseyin Turgut   +3 more
doaj   +1 more source

Response to combination therapy with interferon alfa-2a and ribavirin in chronic hepatitis C according to a TNF-alpha promoter polymorphism [PDF]

, 2003
Background. Tumor necrosis factor-alpha (TNF-alpha) is involved in the pathogenesis of chronic active hepatitis C. Polymorphisms in the promoter region of the TNF-alpha gene can alter the TNF-alpha expression and modify the host immune response.
Folwaczny, Christian, Glas, J., Konig, A., Martin, K., Schaefer, M., Schiemann, Uwe, Schmidt, F., Simperl, C., Torok, P.   +8 more
core   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source