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ETIOLOGICAL CHARACTERISTICS OF CHRONIC VIRAL HEPATITIS IN THE KHOREZM REGION OF UZBEKISTAN
A study of the etiological structure of chronic viral hepatitis is presented, taking into account the assessment of the stage of the pathological process and the genotypic affiliation of pathogens in the Khorezm region of the Republic of Uzbekistan.
Shavkat R. Yusupov +4 more
doaj +1 more source
Clinical and psychopathological features of the course and outcome of the first psychotic episode.
Recently it has been established that cytokines are involved in the regulation of the body’s defense reactions in response to a pathogen and form an independent system for regulating homeostasis.
Yuri Bazhora +4 more
doaj +1 more source
Chronic hepatitis B affects more than 250 million individuals worldwide, putting them at risk of developing liver cirrhosis and liver cancer. While antiviral immune responses are key to eliminating hepatitis B virus (HBV) infections, insufficient ...
Percy A. Knolle +4 more
doaj +1 more source
Background Hepatitis E virus infection usually causes an acute and self-resolving hepatitis. In areas where chronic hepatitis B virus infection is prevalent, acute hepatitis E virus superinfection on chronic hepatitis B virus infection occurs ...
Chau-Ting Yeh +3 more
doaj +1 more source
The term chronic hepatitis is used to include prolonged inflammation of the liver following an attack of acute viral hepatitis, either icteric or anicteric, or chronic active hepatitis, of unknown aetiology. We accept the Fogarty proceedings definition of chronic hepatitis as inflammation of the liver for six months or more, although the duration of ...
openaire +4 more sources
Background/Purpose: Effective antiviral-therapy can reduce the risk of liver cirrhosis related hepatocellular carcinoma in patients with chronic hepatitis B and hepatitis C. Yet, the difference of hepatocellular carcinoma development in chronic hepatitis
Ming-Tsung Lin +8 more
doaj +1 more source
The persistence of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) is a key obstacle for HBV cure. This study aims to comprehensively assess the effect of interferon (IFN) and small-interfering RNA (siRNA) combination on the cccDNA ...
Kongying Hu +10 more
doaj +1 more source
Summary: Chronic hepatitis is major health problem that affect liver function with high morbidity and mortality in developing countries. Macerated liquorice root used since several decades as one of traditional drink in Egypt.
H.A. Abdel Maksoud +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

