Results 11 to 20 of about 326,926 (265)
Management and Treatment of Patients with Chronic Hepatitis B: Towards Personalized Medicine
Viruses, 2022 The currently available antiviral treatments (Peg-Interferon-α and Nucleos(t)ide Analogues, NA) for chronic hepatitis B (CHB) achieve a functional cure (serum HBsAg and HDV-DNA clearance) of HBV infection in a limited number of patients.
Piero Colombatto +3 more
doaj +1 more source
OBESITY AND DYSLIPIDEMIA IN CHILDREN WITH CHRONIC HEPATITIS [PDF]
Romanian Journal of Pediatrics, 2016 Chronic hepatitis association with various types of dyslipidemia is a reality not only for the obese pediatric patient, in which we expect to find hypercholesterolemia and / or hypertriglyceridemias, but also for normal weight children with hepatitis ...
Alice N. Azoicai +7 more
doaj +1 more source
Different profiles of neurocognitive impairment in patients with hepatitis B and C virus infections
Scientific Reports, 2022 The direct impact of chronic hepatitis B and hepatitis C on neurocognition remains elusive due to the frequent comorbidities, and the domains of the neurocognitive functions affected have rarely been investigated comprehensively.
Chun-Hsiang Tan +9 more
doaj +1 more source
Viruses and miRNAs: More Friends than Foes
Frontiers in Microbiology, 2017 There is evidence that eukaryotic miRNAs (hereafter called host miRNAs) play a role in the replication and propagation of viruses. Expression or targeting of host miRNAs can be involved in cellular antiviral responses.
Patrice Bruscella +5 more
doaj +1 more source
Postgraduate Medicine, 1974 Chronic hepatitis may be viral or "lupoid" or may be related to drug use, alcoholism, or Wilson's disease. This article outlines the routine and special laboratory investigations that are indicated when the presence of chronic hepatitis is suspected from symptoms referable to the liver or from biochemical or physical abnormalities in an asymptomatic ...
openaire +5 more sources
A deep learning model to predict RNA-Seq expression of tumours from whole slide images
Nature Communications, 2020 RNA-sequencing of tumour tissue can provide important diagnostic and prognostic information but this is costly and not routinely performed in all clinical settings. Here, the authors show that whole slide histology slides—part of routine care—can be used
Benoît Schmauch +13 more
doaj +1 more source
Quality of life in patients with chronic hepatitis C [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2011 Introduction. Hepatitis C virus often causes chronic liver disease reducing physical, mental and social functions in these patients. Objective. The aim of this investigation was analysis of the quality of life in chronic hepatitis C patients compared ...
Pavić Slađana +3 more
doaj +1 more source
Gut and Liver, 2011 The goal of antiviral therapy for patients with chronic hepatitis C virus (HCV) infection is to attain a sustained virologic response (SVR), which is defined as undetectable serum HCV-RNA levels at 6 months after the cessation of treatment. Major improvements in antiviral therapy for chronic hepatitis C have occurred in the past decade. The addition of
Jang, Jae Young, Chung, Raymond T.
openaire +3 more sources
Nature Communications, 2016 Cyclophilins play a key role in the life cycle of many viruses and represent important drug targets for broad-spectrum antiviral therapies. Here, the authors use fragment-based drug discovery to develop non-peptidic inhibitors of human cyclophilins with ...
Abdelhakim Ahmed-Belkacem +12 more
doaj +1 more source
Lipoprotein Receptors and Lipid Enzymes in Hepatitis C Virus Entry and Early Steps of Infection
Scientifica, 2012 Viruses are obligate intracellular agents that depend on host cells for successful propagation, hijacking cellular machineries to their own profit. The molecular interplay between host factors and invading viruses is a continuous coevolutionary process ...
Eve-Isabelle Pécheur
doaj +1 more source