Results 41 to 50 of about 326,926 (265)

Cross-sectional study of changes in physical activity behavior during the COVID-19 pandemic among US adults

International Journal of Behavioral Nutrition and Physical Activity, 2021
Background Physical activity (PA) provides numerous health benefits relevant to the COVID-19 pandemic. However, concerns exist that PA levels may have decreased during the pandemic thus exacerbating health disparities.
Kathleen B. Watson, Geoffrey P. Whitfield, George Huntzicker, John D. Omura, Emily Ussery, Tiffany J. Chen, Robyn Neblett Fanfair   +6 more
doaj   +1 more source

Autoimmune Hepatitis Leading to Liver Cirrhosis: A Case Report

Journal of Nepal Medical Association, 2022
Autoimmune hepatitis is a rare form of chronic liver inflammation that begins as acute hepatitis and progresses to chronic liver disease. It presents with varied clinical features from acute hepatitis to chronic liver diseases like chronic viral ...
Moon Shrestha, Sudip Chandra Subedi, Sangam Shah, Jeny Acharya, Milan Regmi, Neha Mehta   +5 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Estimation of Thyroid Gland and Pancreatic Functioning in Patients with Chronic Hepatitis B and C Combined with Autoimmune Thyroiditis and without it

Mìžnarodnij Endokrinologìčnij Žurnal, 2012
Chronic viral hepatitis is one of the most urgent problems of the healthcare. Viral hepatitis is not restricted with liver damage; they are like systemic disease proceeding with obligate development of extrahepatic manifestations.
Kh.T. Rustamova, M.P. Mirakhmedova, Kh.N. Abdullayeva   +2 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Costs of Treatment, Follow-Up, and Complications of Chronic Hepatitis B and Hepatitis C Infections

Balkan Medical Journal, 2013
Background: Few studies have addressed the indirect costs of chronic hepatitis B and C, and none has assessed the real costs of these conditions, including indirect costs caused by loss of work, in Turkey. Aims: This study therefore analysed the costs of
Fatma Banu Karahasanoğlu, Ali Asan, Suzan Sacar, Hüseyin Turgut   +3 more
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Interferon-α for Immune Modulation in Chronic Hepatitis B Toward Functional Cure

Viruses
Chronic hepatitis B (CHB) remains a major global health challenge, largely due to the persistence of covalently closed circular DNA (cccDNA) and impaired host immunity.
Asha Ashuo, Jia Liu, Zhenghong Yuan, Jieliang Chen   +3 more
doaj   +1 more source

Health-related quality of life in patients with autoimmune hepatitis: A questionnaire survey. [PDF]

PLoS ONE, 2018
AIM:Health-related quality of life is impaired in patients with autoimmune hepatitis, but the association between health-related quality of life and patients' backgrounds remains unknown.
Atsushi Takahashi, Kei Moriya, Hiromasa Ohira, Teruko Arinaga-Hino, Mikio Zeniya, Takuji Torimura, Masanori Abe, Akinobu Takaki, Jong-Hon Kang, Ayano Inui, Tomoo Fujisawa, Kaname Yoshizawa, Yoshiyuki Suzuki, Nobuhiro Nakamoto, Kazuhiko Koike, Hitoshi Yoshiji, Aya Goto, Atsushi Tanaka, Zobair M Younossi, Hajime Takikawa, Japan AIH Study Group   +20 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source