Results 81 to 90 of about 1,109,482 (395)

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao   +6 more
wiley   +1 more source

The Iowa Viral Hepatitis Strategic Plan 2012-2016, August 26, 2014 [PDF]

open access: yes, 2014
Since the creation of the first viral hepatitis plan in 2004 several documents and advancements have been released that help Iowa plan and prioritize this revision of our hepatitis plan.

core  

Liver disease in chelated transfusion-dependent thalassemics: the role of iron overload and chronic hepatitis C. [PDF]

open access: yes, 2008
Iron overload and hepatitis virus C infection cause liver fibrosis in thalassemics. In a monocentric retrospective analysis of liver disease in a cohort of 191 transfusion-dependent thalassemics, in 126 patients who had undergone liver biopsy (mean age ...
ALMASIO, Pier Luigi   +12 more
core   +1 more source

Management of chronic hepatitis C [PDF]

open access: yesPostgraduate Medical Journal, 2005
AbstractHepatitis C virus (HCV) infection is transmitted primarily through percutaneous exposure to blood, and most infections are associated with injection drug use. Progression to chronic HCV occurs in 55% to 86% of infected people, and persistent infection is a major cause of cirrhosis, end stage liver disease, and hepatocellular carcinoma.
V, Lo Re, J R, Kostman
openaire   +2 more sources

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

open access: yesAdvanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi   +18 more
wiley   +1 more source

Fulminant hepatitis B reactivation leading to liver transplantation in a patient with chronic hepatitis C treated with simeprevir and sofosbuvir: a case report

open access: yesJournal of Medical Case Reports, 2015
IntroductionHepatitis B and C coinfection is commonly seen in clinical practice. In coinfected individuals, high levels of hepatitis C viremia are often associated with low levels of serum hepatitis B DNA. Hepatitis B reactivation in hepatitis C-infected
Alexander R. Ende   +4 more
semanticscholar   +1 more source

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

open access: yesAdvanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa   +23 more
wiley   +1 more source

Identification of Histopathologic Criteria to Differentiate Autoimmune Hepatitis (AIH) from Chronic Viral Hepatitis (B, C) in Liver Biopsy Samples

open access: yesمجله دانشکده پزشکی اصفهان, 2017
Background: Chronic hepatitis is a common disease in the community. Differential diagnosis of hepatitis is very important in the treatment of this disease; as applying the wrong treatment method can lead to reinforcement and aggravate.
Mohammadhossein Sanei   +3 more
doaj  

Hepatite crónica: o espectro etiológico. Implicações para o tratamento.

open access: yesActa Médica Portuguesa, 1993
The prevalence of chronic hepatitis and its different aetiologies was studied in all patients above 10 years of age seen in the specialised outpatient clinic of our hospital over a 3 year period.
J Velosa   +4 more
doaj   +1 more source

Evaluation of an enzyme immunoassay for hepatitis C virus antibody detection using a recombinant protein derived from the core region of hepatitis C virus genome [PDF]

open access: yes, 2000
This study was undertaken to evaluate an enzyme immunoassay (EIA) for hepatitis C virus antibody detection (anti-HCV), using just one antigen. Anti-HCV EIA was designed to detect anti-HCV IgG using on the solid-phase a recombinant C22 antigen localized ...
Ferraz, Maria Lucia Cardoso Gomes   +7 more
core   +4 more sources

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