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Hepatitis C Virus [PDF]

Trends in Microbiology, 2019
Hepatitis C virus (HCV) is an enveloped, RNA virus transmitted through blood-to-blood contact. It infects humans only and primarily targets liver cells. HCV evades innate and adaptive immunity and establishes chronic infections in 70% of cases. If untreated, 20% of patients develop liver cirrhosis, and a fraction of these progress to hepatocellular ...
Pietschmann, Thomas, Brown, Richard J P
openaire   +3 more sources

Strong correlation by ultrasonography of hepatomegaly and the presence of co-infection in HIV/HCV cirrhotic patients

Brazilian Journal of Infectious Diseases, 2013
Objectives: Progression of hepatic fibrosis is accelerated in patients co-infected with human immunodeficiency virus and hepatitis C virus compared to hepatitis C virus mono-infected patients.
Denise Cerqueira Paranaguá Vezozzo, Maria Cassia Mendes-Correa, Marlone Cunha-Silva, Mónica Viviana Alvarado-Mora, João Ítalo Dias França, José Luiz Sebba, Antonio Carlos Nicodemo, Claudia P.M.S. Oliveira, Flair José Carrilho   +8 more
doaj   +5 more sources

Awareness and prevalence of hepatitis C virus infection among pregnant women in Nigeria: A national pilot cross-sectional study

Women's Health, 2021
Background: There are no national data on hepatitis C virus awareness and burden among pregnant women to justify its routine screening. Objectives: To investigate awareness, seroprevalence and risk factors for hepatitis C virus infection among pregnant ...
George Uchenna Eleje, Ayyuba Rabiu, Ikechukwu Innocent Mbachu, Godwin Otuodichinma Akaba, Olabisi Morebise Loto, Hadiza Abdullahi Usman, Preye Owen Fiebai, Rebecca Chinyelu Chukwuanukwu, Ngozi Nneka Joe-Ikechebelu, Chike Henry Nwankwo, Stephen Okoroafor Kalu, Chinyere Ukamaka Onubogu, Chukwuanugo Nkemakonam Ogbuagu, Shirley Nneka Chukwurah, Chinwe Elizabeth Uzochukwu, Samuel Oluwagbenga Inuyomi, Bukola Abimbola Adesoji, Uchenna Chukwunonso Ogwaluonye, Ekene Agatha Emeka, Richard Obinwanne Egeonu, Odion Emmanuel Igue, Chiamaka Henrietta Jibuaku, Ogbonna Dennis Okoro, Prince Ogbonnia Aja, Chiamaka Perpetua Chidozie, Hadiza Sani Ibrahim, Fatima Ele Aliyu, Aisha Ismaila Numan, Solace Amechi Omoruyi, Ijeoma Chioma Oppah, Ubong Inyang Anyang, Aishat Ahmed, Osita Samuel Umeononihu, Eric Okechukwu Umeh, Sussan Ifeyinwa Nweje, Ifeoma Clara Ajuba, Chukwuemeka Chukwubuikem Okoro, Arinze Anthony Onwuegbuna, Emeka Philip Igbodike, Ifeanyi Kingsley Nwaeju, Ibrahim Adamu Yakasai, Oliver Chukwujekwu Ezechi, Joseph Ifeanyichukwu Ikechebelu   +42 more
doaj   +1 more source

Seroprevalence of hepatitis A virus, hepatitis B virus, hepatitis C virus, and syphilis among human immunodeficiency virus-infected people at a university hospital, Turkey

Archives of Medical Science, 2020
Introduction Infections such as viral hepatitis and syphilis that share similar transmission routes with human immunodeficiency virus (HIV) may adversely affect the course of the disease.
Heval Can Bilek, Aydın Deveci, Esra Aksakal Tanyel   +2 more
doaj   +1 more source

Hepatitis C virus core antigen assay: can we think beyond convention in resource limited settings?

Brazilian Journal of Infectious Diseases, 2013
Hepatitis C virus infects over 15 million patients from India and 2.86 million from Brazil. Detection of anti-hepatitis C virus antibodies has limited sensitivity during acute phase: the pre-seroconversion window period.
Anita Chakravarti, Mayank S. Chauhan, Gaurav Dogra, Sayantan Banerjee   +3 more
doaj   +5 more sources

Hepatitis C Virus and Hepatitis B Virus Co-Infection

Viruses, 2020
Hepatitis C virus (HCV) and hepatitis B virus (HBV) co-infection can be encountered in either virus endemic countries. Co-infection can also be found in populations at risk of parenteral transmission.
Yi-Fen Shih, Chun-Jen Liu
doaj   +1 more source

Hepatitis C virus [PDF]

Archives of Virology, 1991
HepCV is the major cause of NANB PT hepatitis and is also implicated as the cause in a large proportion of sporadic cases of NANBH. Chronic infection with HepCV has also been linked to the development of hepatocellular carcinoma. Chimpanzees and marmosets are the only animals found to be experimentally infectable and the virus has not been propagated ...
openaire   +2 more sources

Rad51 Interacts with Non-structural 3 Protein of Hepatitis C Virus and Regulates Viral Production

Frontiers in Microbiology, 2017
Hepatitis C virus (HCV) is a leading cause of chronic liver disease affecting over 170 million people worldwide. Chronic infection with HCV progresses to liver fibrosis, cirrhosis, and hepatocellular carcinoma.
Kidong Son, Kidong Son, Kidong Son, Tram T. T. Nguyen, Tram T. T. Nguyen, Jae-Woong Choi, Jae-Woong Choi, Long V. Pham, Long V. Pham, Trang T. D. Luong, Trang T. D. Luong, Yun-Sook Lim, Soon B. Hwang, Soon B. Hwang   +13 more
doaj   +1 more source

Abl Tyrosine Kinase Regulates Hepatitis C Virus Entry

Frontiers in Microbiology, 2017
Abl is a central regulator of multiple cellular processes controlling actin dynamics, proliferation, and differentiation. Here, we showed that knockdown of Abl impaired hepatitis C virus (HCV) propagation.
Saehong Min, Saehong Min, Yun-Sook Lim, Dongjo Shin, Dongjo Shin, Chorong Park, Chorong Park, Jae-Bong Park, Seungtaek Kim, Marc P. Windisch, Soon B. Hwang, Soon B. Hwang   +11 more
doaj   +1 more source

Hepatitis B and C virus infections and associated factors among HIV-positive and HIV-negative tuberculosis patients in public health facilities, Northeast Ethiopia: A comparative cross-sectional study

SAGE Open Medicine, 2023
Objective: Viral hepatitis, particularly hepatitis B virus and hepatitis C virus, is the leading cause of global liver-related morbidity and mortality.
Alemu Gedefie, Abdurahaman Seid, Genet Molla Fenta, Mihret Tilahun, Agumas Shibabaw, Abdurrahman Ali   +5 more
doaj   +1 more source