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HCV reinfection after HCV therapy among HIV/HCV‐coinfected individuals in Europe [PDF]

open access: yesHIV Medicine, 2021
AbstractObjectivesAlthough direct‐acting antivirals (DAAs) can clear HCV in nearly all HIV/HCV‐coinfected individuals, high rates of reinfection may hamper efforts to eliminate HCV in this population. We investigated reinfection after sustained virological response (SVR) in HIV/HCV‐coinfected individuals in Europe.MethodsFactors associated with odds of
Amele S.   +199 more
openaire   +7 more sources

Interference between miR-21/PTEN/E-Cadherin and Epithelial-Mesenchymal Transition in Various Stages of Chronic HCV Infection [PDF]

open access: yesJournal of Bioscience and Applied Research, 2022
Hepatocellular carcinoma (HCC) is a major complication associated with hepatitis C viral infection (HCV). The epithelial-mesenchymal transition (EMT) is critical in HCC invasion and metastasis.
Yasser Ali   +5 more
doaj   +1 more source

Comparative study on anti-HCV testing using plasma, dried plasma spots (DPS), and dried blood spots (DBS)Highlights

open access: yesBiosafety and Health, 2021
The aim of this study was to evaluate the performance of an assay using dried plasma spot (DPS) and dried blood spot (DBS) samples for the serological detection of anti-hepatitis C virus (HCV) antibodies.
Jieqiong Ma   +6 more
doaj   +1 more source

HCV and Lymphoproliferation [PDF]

open access: yesClinical and Developmental Immunology, 2012
Hepatitis C virus (HCV) infection is a serious public health problem because of its worldwide diffusion and sequelae. It is not only a hepatotropic but also a lymphotropic agent and is responsible not only for liver injury—potentially evolving to cirrhosis and hepatocellular carcinoma—but also for a series of sometimes severely disabling extrahepatic ...
ZIGNEGO, ANNA LINDA   +2 more
openaire   +6 more sources

Development and evaluation of serological screening based on one dried plasma spot for HIV, syphilis, and HCV

open access: yesVirology Journal, 2023
Background In the effort to prevent and control HIV/AIDS, China has established a national sentinel surveillance system. However, some sentinel sites face limitations in environmental resources and accessibility, prompting the exploration of alternative ...
Jie-qiong Ma   +5 more
doaj   +1 more source

HCV core antigen and HCV-RNA in HIV/HCV co-infected patients with different HCV genotypes [PDF]

open access: yesBMC Infectious Diseases, 2014
A good correlation between HCV core antigen (HCVAg) and different HCV-RNA assays has been described, but little data are available in HCV/HIV co-infection. We aimed to evaluate HCVAg in comparison with HCV-RNA and to determine their kinetics during antiviral treatment in selected HCV/HIV co-infected patients.355 samples from 286 HCV/HIV co-infected ...
Garbuglia, Anna Rosa   +6 more
openaire   +2 more sources

Recommendations for Implementing Hepatitis C Virus Care in Homeless Shelters: The Stakeholder Perspective. [PDF]

open access: yes, 2020
Compared with the general population, homeless individuals are at higher risk of hepatitis C infection (HCV) and may face unique barriers in receipt of HCV care.
Anderson, August   +8 more
core   +1 more source

Changes in DNA methylation profile in liver tissue during progression of HCV-induced fibrosis to hepatocellular carcinoma

open access: yesВавиловский журнал генетики и селекции, 2023
In this study we compared methylation levels of 27,578 CpG sites between paired samples of the tumor and surrounding liver tissues with various degrees of damage (fibrosis, cirrhosis) in HCV-induced hepatocellular carcinoma (HCC) patients, as well as ...
I. A. Goncharova   +4 more
doaj   +1 more source

miRNA-122 from Laboratory biomarker to the treatment of HCV [PDF]

open access: yesJournal of Bioscience and Applied Research, 2017
Hepatitis C virus (HCV) is an important human pathogen that infects as many as 185 million persons worldwide, In the long-term, this can lead to advanced liver fibrosis, cirrhosis, and hepatocellular carcinoma HCC, there is currently no vaccine for ...
Ahmed Yameny
doaj   +1 more source

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