Results 1 to 10 of about 122,325 (212)

Feasibility of anti-HCV reflex HCV Ag screening strategy in an HCV endemic community

Journal of the Formosan Medical Association, 2021
The HCV core antigen (HCV Ag) assay displays high sensitivity and strong correlation with HCV RNA. However, the feasibility of anti-HCV reflex HCV Ag screening in a community-wide setting is rarely discussed.We performed a two-phase community-based hepatitis C screen in an HCV-prone area of central Taiwan.
Wei-Ming Chen, Nien-Tzu Hsu, Mei-Yen Chen   +2 more
exaly   +5 more sources

Screening for HCV [PDF]

Canadian Medical Association Journal, 2014
We applaud Shah and colleagues[1][1] for raising the issue of establishing a Canadian screening program for hepatitis C. We agree that hepatitis C shows the hallmarks of an infectious disease suited to a screening program,[2][2] but we are concerned that the extrapolation of American data into ...
Fiona G, Kouyoumdjian, Aaron, Orkin, Kathleen, Dooling, Michael, Schwandt   +3 more
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HCV and Lymphoproliferation [PDF]

Clinical and Developmental Immunology, 2012
Hepatitis C virus (HCV) infection is a serious public health problem because of its worldwide diffusion and sequelae. It is not only a hepatotropic but also a lymphotropic agent and is responsible not only for liver injury—potentially evolving to cirrhosis and hepatocellular carcinoma—but also for a series of sometimes severely disabling extrahepatic ...
ZIGNEGO, ANNA LINDA, GIANNINI, CARLO, GRAGNANI, LAURA   +2 more
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HCV and the kidney [PDF]

Liver International, 2016
AbstractChronic hepatitis C (CHC) is significantly associated with a risk of renal deterioration over time. Renal impairment, especially stage 4–5 chronic kidney disease, increases the risk of: (i) the prevalence and incidence (in dialysis/transplantation) of hepatitis C virus (HCV) infection; (ii) liver deterioration during kidney transplantation and (
Marion, Corouge, Anaïs, Vallet-Pichard, Stanislas, Pol   +2 more
openaire   +2 more sources

HCV core antigen and HCV-RNA in HIV/HCV co-infected patients with different HCV genotypes [PDF]

BMC Infectious Diseases, 2014
A good correlation between HCV core antigen (HCVAg) and different HCV-RNA assays has been described, but little data are available in HCV/HIV co-infection. We aimed to evaluate HCVAg in comparison with HCV-RNA and to determine their kinetics during antiviral treatment in selected HCV/HIV co-infected patients.355 samples from 286 HCV/HIV co-infected ...
Garbuglia, Anna Rosa, Monachetti, Alessia, Galli, Claudio, Sabatini, Rosella, Ferreri, Monica Lucia, Capobianchi, Maria Rosaria, Bagnarelli, Patrizia   +6 more
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HCV and Oxidative Stress: Implications for HCV Life Cycle and HCV‐Associated Pathogenesis [PDF]

Oxidative Medicine and Cellular Longevity, 2016
HCV (hepatitis C virus) is a member of the Flaviviridae family that contains a single‐stranded positive‐sense RNA genome of approximately 9600 bases. HCV is a major causative agent for chronic liver diseases such as steatosis, fibrosis, cirrhosis, and hepatocellular carcinoma which are caused by multifactorial processes.
Medvedev, Regina, Ploen, Daniela, Hildt, Eberhard   +2 more
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Comparison of HCV core antigen and anti-HCV with HCV RNA results

African Health Sciences, 2015
The measurement of anti-HCV antibodies using immunological methods and the confirmation of viral nuclear acid based on molecular methods is important in diagnosis and follow-up of the HCV infection.In this study, we aimed to analyse HCV core Antigen positivity among anti-HCV antibody positive sera to determine the significance of testing of HCV core Ag
Ayse, Aynali, Emel, Sesli Cetin, Sueleyman, Oenal, Selcuk, Kaya, Buket, Cicioglu Aridogan   +4 more
openaire   +6 more sources

Effect of combined siRNA of HCV E2 gene and HCV receptors against HCV [PDF]

Virology Journal, 2011
Hepatitis C virus (HCV) is a major threat as almost 3% of the world's population (350 million individual) and 10% of the Pakistani population is chronically infected with this virus. RNA interference (RNAi), a sequence-specific degradation process of RNA, has potential to be used as a powerful alternative molecular therapeutic approach in spite of the ...
Ashfaq Usman Alli A, Ahmad Waqar, Khan Mahwish, Ijaz Bushra, Samreen Baila, Khaliq Saba, Jahan Shah, Hassan Sajida   +7 more
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HCV avidity as a tool for detection of recent HCV infection: Sensitivity depends on HCV genotype [PDF]

Journal of Medical Virology, 2017
Accurate detection of incident hepatitis C virus (HCV) infection is required to target and evaluate public health interventions, but acute infection is largely asymptomatic and difficult to detect using traditional methods. Our aim was to evaluate a previously developed HCV avidity assay to distinguish acute from chronic HCV infection.
Samantha J. Shepherd, Scott A. McDonald, Norah E. Palmateer, Rory N. Gunson, Celia Aitken, Gregory J. Dore, David J. Goldberg, Tanya L. Applegate, Andrew R. Lloyd, Behzad Hajarizadeh, Jason Grebely, Sharon J. Hutchinson   +11 more
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HCV reinfection after HCV therapy among HIV/HCV‐coinfected individuals in Europe

HIV Medicine, 2021
AbstractObjectivesAlthough direct‐acting antivirals (DAAs) can clear HCV in nearly all HIV/HCV‐coinfected individuals, high rates of reinfection may hamper efforts to eliminate HCV in this population. We investigated reinfection after sustained virological response (SVR) in HIV/HCV‐coinfected individuals in Europe.MethodsFactors associated with odds of
Amele S., Sandri A. K., Rodger A., Vandekerckhove L., Benfield T., Milinkovic A., Duvivier C., Stellbrink H. -J., Sambatakou H., Chkhartishvili N., Caldeira L., Laguno M., Domingo P., Wandeler G., Gisinger M., Kuzovatova E., Dragovic G., Knysz B., Matulionyte R., Rockstroh J. K., Lundgren J. D., Mocroft A., Peters L., Harxhi A., Losso M., Kundro M., Schmied B., Zangerle R., Karpov I., Vassilenko A., Mitsura V. M., Paduto D., Clumeck N., Wit S. D., Delforge M., Florence E., Vandekerckhove L., Hadziosmanovic V., Begovac J., Machala L., Jilich D., Sedlacek D., Kronborg G., Benfield T., Gerstoft J., Katzenstein T., Pedersen C., Johansen I. S., Ostergaard L., Wiese L., Moller N. F., Nielsen L. N., Zilmer K., Smidt J., Aho I., Viard J. -P., Girard P. -M., Pradier C., Fontas E., Duvivier C., Rockstroh J., Behrens G., Degen O., Stellbrink H. J., Stefan C., Bogner J., Fatkenheuer G., Chkhartishvili N., Sambatakou H., Adamis G., Paissios N., Szlavik J., Gottfredsson M., Devitt E., Tau L., Turner D., Burke M., Shahar E., Hassoun G., Elinav H., Haouzi M., Elbirt D., D'Arminio Monforte A., Esposito R., Mazeu I., Mussini C., Mazzotta F., Gabbuti A., Lazzarin A., Castagna A., Gianotti N., Galli M., Ridolfo A., Sacco L., Uzdaviniene V., Matulionyte R., Staub T., Hemmer R., Dragas S., Stevanovic M., Reiss P., Trajanovska J., Reikvam D. H., Maeland A., Bruun J., Knysz B., Gasiorowski J., Inglot M., Bakowska E., Flisiak R., Grzeszczuk A., Parczewski M., Maciejewska K., Aksak-Was B., Beniowski M., Mularska E., Jablonowska E., Kamerys J., Wojcik K., Mozer-Lisewska I., Rozplochowski B., Zagalo A., Mansinho K., Maltez F., Radoi R., Oprea C., Davila C., Yakovlev A., Trofimora T., Khromova I., Kuzovatova E., Blokhina I. N., Novogrod N., Borodulina E., Vdoushkina E., Ranin J., Tomazic J., Miro J. M., Miro J. M., Martinez E., Garcia F., Blanco J. L., Martinez-Rebollar M., Mallolas J., Callau P., Rojas J., Inciarta A., Moreno S., del Campo S., Clotet B., Jou A., Paredes R., Puig J., Llibre J. M., Santos J. R., Domingo P., Gutierrez M., Mateo G., Sambeat M. A., Laporte J. M., Falconer K., Thalme A., Sonnerborg A., Brannstrom J., Flamholc L., Scherrer A., Weber R., Cavassini M., Calmy A., Furrer H., Battegay M., Schmid P., Kuznetsova A., Mikhalik J., Sluzhynska M., Milinkovic A., Johnson A. M., Simons E., Edwards S., Phillips A., Johnson M. A., Mocroft A., Orkin C., Winston A., Clarke A., Leen C., Karpov I., Losso M., Lundgren J., Rockstroh J., Aho I., Rasmussen L. D., Svedhem V., Wandeler G., Pradier C., Chkhartishvili N., Matulionyte R., Oprea C., Kowalska J. D., Begovac J.   +199 more
openaire   +7 more sources