Results 31 to 40 of about 215,114 (209)

Gender as a factor affecting NK cell activity in patients successfully treated for chronic hepatitis C with direct-acting antivirals

open access: yesCentral European Journal of Immunology, 2021
Chronic hepatitis C (CHC) affects the activity of natural killer (NK) cells, but successful interferon- free treatment partially restores it. The goal of this study was to assess whether gender influences NK functionality.
Agata Zientarska   +8 more
doaj   +1 more source

OE-Abiodun/HIV-HCV-COINFECTION-SIM-CODE: HIV-HCV Co-infection

open access: yes, 2022
MAPLE SIMULATION CODE FOR HIV-HCV MODEL.zip Full Changelog: https://github.com/OE-Abiodun/HIV-HCV-COINFECTION-SIM-CODE/commits/v3.0.
Oluwakemi Elizabeth Abiodun
core   +1 more source

Antiviral therapy of chronic hepatitis C: 30 years success story [PDF]

open access: yesТерапевтический архив, 2019
Exactly 30 years ago, hepatitis C virus was identified. Over the years, tremendous success has been achieved in the treatment of hepatitis C, which is currently considered to be an almost completely curable disease. The review presents the main stages in
D T Abdurakhmanov   +9 more
doaj   +1 more source

HCV treatment for prevention among people who inject drugs: Modeling treatment scale-up in the age of direct-acting antivirals. [PDF]

open access: yes, 2013
UNLABELLED: Substantial reductions in hepatitis C virus (HCV) prevalence among people who inject drugs (PWID) cannot be achieved by harm reduction interventions such as needle exchange and opiate substitution therapy (OST) alone. Current HCV treatment is
Dillon, John   +40 more
core   +1 more source

Effect of combined siRNA of HCV E2 gene and HCV receptors against HCV [PDF]

open access: yesVirology Journal, 2011
Hepatitis C virus (HCV) is a major threat as almost 3% of the world's population (350 million individual) and 10% of the Pakistani population is chronically infected with this virus. RNA interference (RNAi), a sequence-specific degradation process of RNA, has potential to be used as a powerful alternative molecular therapeutic approach in spite of the ...
Ashfaq Usman Alli A   +7 more
openaire   +3 more sources

Association Between DEPDC5 and PNPLA3 Variants and the Risk of Hepatocellular Carcinoma in HCV-Infected Patients in Egypt [PDF]

open access: yesJournal of Bioscience and Applied Research
Hepatocellular carcinoma (HCC) is the most prevalent and life-threatening form of liver cancer worldwide. In Egypt, HCC ranks as the second most common cancer in men and the sixth most common in women.
Osama Roshdy   +4 more
doaj   +1 more source

Accelerated cardiovascular risk after viral clearance in hepatitis C patients with the NAMPT-rs61330082 TT genotype: An 8-year prospective cohort study

open access: yesVirulence, 2021
Involvement of extracellular nicotinamide phosphoribosyltransferase (eNAMPT, i.e., visfatin or pre-B-cell colony-enhancing factor), a cancer metabokine, in chronically hepatitis C virus (HCV)-infected (CHC) patients with sustained virological responses ...
Ming-Ling Chang   +5 more
doaj   +1 more source

Sox4 represses host innate immunity to facilitate pathogen infection by hijacking the TLR signaling networks

open access: yesVirulence, 2021
Toll-like receptors (TLRs) are essential for the protection of the host from pathogen infections by initiating the integration of contextual cues to regulate inflammation and immunity.
Jian Shang   +10 more
doaj   +1 more source

HCV reinfection after HCV therapy among HIV/HCV‐coinfected individuals in Europe

open access: yesHIV Medicine, 2021
AbstractObjectivesAlthough direct‐acting antivirals (DAAs) can clear HCV in nearly all HIV/HCV‐coinfected individuals, high rates of reinfection may hamper efforts to eliminate HCV in this population. We investigated reinfection after sustained virological response (SVR) in HIV/HCV‐coinfected individuals in Europe.MethodsFactors associated with odds of
Amele S.   +199 more
openaire   +7 more sources

Response prediction in chronic hepatitis C by assessment of IP-10 and IL28B-related single nucleotide polymorphisms [PDF]

open access: yes, 2011
Background: High baseline levels of IP-10 predict a slower first phase decline in HCV RNA and a poor outcome following interferon/ribavirin therapy in patients with chronic hepatitis C.
Askarieh Galia   +109 more
core   +1 more source

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