Results 41 to 50 of about 210,178 (301)

Response prediction in chronic hepatitis C by assessment of IP-10 and IL28B-related single nucleotide polymorphisms [PDF]

open access: yes, 2011
Background: High baseline levels of IP-10 predict a slower first phase decline in HCV RNA and a poor outcome following interferon/ribavirin therapy in patients with chronic hepatitis C.
Askarieh Galia   +109 more
core   +1 more source

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

open access: yesHepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro   +17 more
wiley   +1 more source

Sox4 represses host innate immunity to facilitate pathogen infection by hijacking the TLR signaling networks

open access: yesVirulence, 2021
Toll-like receptors (TLRs) are essential for the protection of the host from pathogen infections by initiating the integration of contextual cues to regulate inflammation and immunity.
Jian Shang   +10 more
doaj   +1 more source

HCV reinfection after HCV therapy among HIV/HCV‐coinfected individuals in Europe

open access: yesHIV Medicine, 2021
AbstractObjectivesAlthough direct‐acting antivirals (DAAs) can clear HCV in nearly all HIV/HCV‐coinfected individuals, high rates of reinfection may hamper efforts to eliminate HCV in this population. We investigated reinfection after sustained virological response (SVR) in HIV/HCV‐coinfected individuals in Europe.MethodsFactors associated with odds of
Amele S.   +199 more
openaire   +7 more sources

Attacking the public health crisis of hepatocellular carcinoma at its roots

open access: yesHepatology, EarlyView., 2022
Abstract As the third most common cause of cancer‐related death worldwide with significant mortality rates in the United States, hepatocellular carcinoma has strong association with cirrhosis and chronic hepatitis B virus (HBV) with a growing at‐risk population from the rise in chronic liver disease from alcohol use and nonalcoholic fatty liver disease.
Hannah M. Lee   +3 more
wiley   +1 more source

HCV avidity as a tool for detection of recent HCV infection: Sensitivity depends on HCV genotype [PDF]

open access: yesJournal of Medical Virology, 2017
Accurate detection of incident hepatitis C virus (HCV) infection is required to target and evaluate public health interventions, but acute infection is largely asymptomatic and difficult to detect using traditional methods. Our aim was to evaluate a previously developed HCV avidity assay to distinguish acute from chronic HCV infection.
Samantha J. Shepherd   +11 more
openaire   +3 more sources

Health disparities in chronic liver disease

open access: yesHepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian   +3 more
wiley   +1 more source

Molecular Evaluation of Viral load and Genotype of HCV in Acute and Chronic HCV Patients in Kirkuk City [PDF]

open access: yesKirkuk Journal of Science, 2019
The study aimed at detection of HCV load and genotypes in acute and chronic HCV patients. A cross sectional study was carried out in Kirkuk city from 15th of March 2017 to 15th of November 2017.
Israa Saadoon   +2 more
doaj   +1 more source

Excluding hepatitis C virus (HCV) infection by serology in young infants of HCV infected mothers

open access: yes, 2005
Aim: To identify the age at which HCV infection can be accurately excluded by serology in young children born to HCV-infected mothers and to determine an appropriate schedule of antibody testing, most informative to clinical practice.
FALDELLA, GIACOMO   +7 more
core   +1 more source

Genetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development [PDF]

open access: yes, 2013
Background: Vitamin D insufficiency has been associated with the occurrence of various types of cancer, but causal relationships remain elusive. We therefore aimed to determine the relationship between genetic determinants of vitamin D serum levels and ...
Jörg Bojunga   +127 more
core   +3 more sources

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