Results 41 to 50 of about 215,114 (209)

HCV avidity as a tool for detection of recent HCV infection: Sensitivity depends on HCV genotype [PDF]

open access: yesJournal of Medical Virology, 2017
Accurate detection of incident hepatitis C virus (HCV) infection is required to target and evaluate public health interventions, but acute infection is largely asymptomatic and difficult to detect using traditional methods. Our aim was to evaluate a previously developed HCV avidity assay to distinguish acute from chronic HCV infection.
Samantha J. Shepherd   +11 more
openaire   +3 more sources

Molecular Evaluation of Viral load and Genotype of HCV in Acute and Chronic HCV Patients in Kirkuk City [PDF]

open access: yesKirkuk Journal of Science, 2019
The study aimed at detection of HCV load and genotypes in acute and chronic HCV patients. A cross sectional study was carried out in Kirkuk city from 15th of March 2017 to 15th of November 2017.
Israa Saadoon   +2 more
doaj   +1 more source

A multi-variant, viral dynamic model of genotype 1 HCV to assess the in vivo evolution of protease-inhibitor resistant variants [PDF]

open access: yes, 2010
Variants resistant to compounds specifically targeting HCV are observed in clinical trials. A multi-variant viral dynamic model was developed to quantify the evolution and in vivo fitness of variants in subjects dosed with monotherapy of an HCV protease ...
Stefan Zeuzem   +36 more
core   +2 more sources

Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation [PDF]

open access: yes, 2010
End-stage liver disease caused by chronic hepatitis C virus (HCV) infection is a leading cause for liver transplantation (LT). Due to viral evasion from host immune responses and the absence of preventive antiviral strategies, reinfection of the graft is
Pessaux, Patrick   +38 more
core   +1 more source

Cryoglobulinemia and hepatitis C virus

open access: yesЖурнал инфектологии, 2014
The review presents recent data on cryoglobulinemiaassociated with a hepatitis C virus: prevalence, pathogenesis, clinical manifestations, laboratory diagnostics, approaches to therapy.
N. V. Dunaeva, E. V. Esaulenko
doaj   +1 more source

Genetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development [PDF]

open access: yes, 2013
Background: Vitamin D insufficiency has been associated with the occurrence of various types of cancer, but causal relationships remain elusive. We therefore aimed to determine the relationship between genetic determinants of vitamin D serum levels and ...
Jörg Bojunga   +150 more
core   +3 more sources

Evaluating the utility of public-facing jail registers to inform public health practice, Washington state 2023

open access: yesBMC Public Health
Background Data on criminal justice system involvement can support public health efforts in ways that have been recognized for decades, but data protections and jurisdictional boundaries can make data sharing difficult.
Steven Erly   +6 more
doaj   +1 more source

Prevalence of transfusion-transmitted infections among blood donors in Koforidua, Ghana, 2016

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: Transfusion-transmitted infections (TTIs) are infections of public health concern since they have the potential to be transferred from person to person through blood transfusion. This study determined the prevalence of HIV, HBV, HCV, and
Holy Alomatu   +6 more
doaj   +1 more source

Sustained virological response 12 versus sustained virological response 24 as evaluation endpoints in chronic hepatitis C virus Egyptian patients treated with sofosbuvir-based regimens

open access: yesThe Egyptian Journal of Internal Medicine, 2019
Background The recommended reliance on 12 weeks posttreatment sustained virological response (SVR12) instead of SVR24 was validated for treatment evaluation. Aim Judging claimed concordance between SVR12 and SVR24.
Maha M Elsabaawy   +9 more
doaj   +1 more source

Reduction of Liver Fibrosis After Treatment with Elbasvir/Grazoprevir in Patients with Hepatitis C Infection in Chronic Kidney Disease on Hemodialysis, a Quasi-Experimental Study

open access: yesThe Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2021
Background: Approximately 5-60% of hemodialysis patients have comorbid of hepatitis C virus (HCV) infection. The survival rate of hemodialysis patients HCV is lower than those without HCV due to the risk of liver fibrosis and cardiovascular disease.
Bayu Laksono   +4 more
doaj   +1 more source

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