Results 41 to 50 of about 210,178 (301)
Response prediction in chronic hepatitis C by assessment of IP-10 and IL28B-related single nucleotide polymorphisms [PDF]
, 2011 Background: High baseline levels of IP-10 predict a slower first phase decline in HCV RNA and a poor outcome following interferon/ribavirin therapy in patients with chronic hepatitis C.Askarieh Galia, Neumann, A.U. (Avidan), Söderholm, Jonas,, Magnus Lindh, Avidan U Neumann, Stephanie Bibert, Soderholm, J, Askarieh, Galia,, Romero, A. (Ana), Group, DITTO-HCV Study, Jean-Michel Pawlotsky, Lindh, M., Negro, F, Söderholm, J., Lindh, M, Missale, Gabriele, Lagging, Martin,, Askarieh, G., Haagmans, Bart L, Romero, Ana, Hellstrand, K. (Kristoffer), Bochud Pierre-Yves, Lagging, Martin, Romero, A, null null, Söderholm Jonas, Haagmans, Bart L., Neumann, AU (Avidan), Gabriele Missale, Ferrari, C., Negro, F., Pawlotsky, J.M., Lindh Magnus, Negro Francesco, Avidan U. Neumann, Pierre-Yves Bochud, Lindh, Magnus, Johan Westin, Zeuzem Stefan, Lindh, M. (Magnus), Missale Gabriele, Bochud, Pierre Yves, Bibert, S., Bochud, P.Y., Galia Askarieh, Lagging Martin, Ferrari Carlo, Bibert, Stephanie, Hellstrand, Kristoffer, Zeuzem, S., Neumann, Avidan U., Haagmans, B.L., DITTO-HCV Study Group, Neumann, A.U., Lindh, Magnus,, Francesco Negro, Westin, J., Söderholm, J. (Jonas), Zeuzem, S. (Stefan), Söderholm, Jonas, Ferrari, Carlo, Martin Lagging, Neumann Avidan U., Zeuzem, Stefan, Neumann, Avidan U, Zeuzem, S, Hellstrand Kristoffer, Westin, Johan, Bart L Haagmans, Romero, A., Lagging, M. (Martin), Hellstrand, K., Haagmans, Bart, Bibert Stephanie, Hellstrand, K, Bart L. Haagmans, Missale, G. (Gabriele), Pawlotsky, Jean Michel, Pawlotsky, Jean-Michel, Ferrari, C. (Carlo), Carlo Ferrari, Bochud, P-Y. (Pierre-Yves), Haagmans Bart L., Askarieh, G, Lagging, M., Missale, G., Stefan Zeuzem, Kristoffer Hellstrand, Ferrari, C, Westin, J. (Johan), Askarieh, Galia, Bibert, S, Lagging, M, Westin, Johan,, Hellstrand, Kristoffer,, Westin, J, Haagmans, B.L. (Bart), Romero Ana, Jonas Söderholm, Pawlotsky Jean-Michel, Westin Johan, Askarieh, G. (Galia), Negro, Francesco, Bochud, PY, Bochud, Pierre-Yves, Pawlotsky, JM, Pawlotsky, J-M. (Jean-Michel), Missale, G, Romero, Ana,, Ana Romero +109 morecore +1 more sourceMitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis
Hepatology, EarlyView., 2022 Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims
Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah +17 morewiley +1 more sourceSox4 represses host innate immunity to facilitate pathogen infection by hijacking the TLR signaling networks
Virulence, 2021 Toll-like receptors (TLRs) are essential for the protection of the host from pathogen infections by initiating the integration of contextual cues to regulate inflammation and immunity.Jian Shang, Yuan Zheng, Jiayin Mo, Wenbiao Wang, Zhen Luo, Yongkui Li, Xulin Chen, Qiwei Zhang, Kailang Wu, Weiyong Liu, Jianguo Wu +10 moredoaj +1 more sourceHCV reinfection after HCV therapy among HIV/HCV‐coinfected individuals in Europe
HIV Medicine, 2021 AbstractObjectivesAlthough direct‐acting antivirals (DAAs) can clear HCV in nearly all HIV/HCV‐coinfected individuals, high rates of reinfection may hamper efforts to eliminate HCV in this population. We investigated reinfection after sustained virological response (SVR) in HIV/HCV‐coinfected individuals in Europe.MethodsFactors associated with odds of Amele S., Sandri A. K., Rodger A., Vandekerckhove L., Benfield T., Milinkovic A., Duvivier C., Stellbrink H. -J., Sambatakou H., Chkhartishvili N., Caldeira L., Laguno M., Domingo P., Wandeler G., Gisinger M., Kuzovatova E., Dragovic G., Knysz B., Matulionyte R., Rockstroh J. K., Lundgren J. D., Mocroft A., Peters L., Harxhi A., Losso M., Kundro M., Schmied B., Zangerle R., Karpov I., Vassilenko A., Mitsura V. M., Paduto D., Clumeck N., Wit S. D., Delforge M., Florence E., Vandekerckhove L., Hadziosmanovic V., Begovac J., Machala L., Jilich D., Sedlacek D., Kronborg G., Benfield T., Gerstoft J., Katzenstein T., Pedersen C., Johansen I. S., Ostergaard L., Wiese L., Moller N. F., Nielsen L. N., Zilmer K., Smidt J., Aho I., Viard J. -P., Girard P. -M., Pradier C., Fontas E., Duvivier C., Rockstroh J., Behrens G., Degen O., Stellbrink H. J., Stefan C., Bogner J., Fatkenheuer G., Chkhartishvili N., Sambatakou H., Adamis G., Paissios N., Szlavik J., Gottfredsson M., Devitt E., Tau L., Turner D., Burke M., Shahar E., Hassoun G., Elinav H., Haouzi M., Elbirt D., D'Arminio Monforte A., Esposito R., Mazeu I., Mussini C., Mazzotta F., Gabbuti A., Lazzarin A., Castagna A., Gianotti N., Galli M., Ridolfo A., Sacco L., Uzdaviniene V., Matulionyte R., Staub T., Hemmer R., Dragas S., Stevanovic M., Reiss P., Trajanovska J., Reikvam D. H., Maeland A., Bruun J., Knysz B., Gasiorowski J., Inglot M., Bakowska E., Flisiak R., Grzeszczuk A., Parczewski M., Maciejewska K., Aksak-Was B., Beniowski M., Mularska E., Jablonowska E., Kamerys J., Wojcik K., Mozer-Lisewska I., Rozplochowski B., Zagalo A., Mansinho K., Maltez F., Radoi R., Oprea C., Davila C., Yakovlev A., Trofimora T., Khromova I., Kuzovatova E., Blokhina I. N., Novogrod N., Borodulina E., Vdoushkina E., Ranin J., Tomazic J., Miro J. M., Miro J. M., Martinez E., Garcia F., Blanco J. L., Martinez-Rebollar M., Mallolas J., Callau P., Rojas J., Inciarta A., Moreno S., del Campo S., Clotet B., Jou A., Paredes R., Puig J., Llibre J. M., Santos J. R., Domingo P., Gutierrez M., Mateo G., Sambeat M. A., Laporte J. M., Falconer K., Thalme A., Sonnerborg A., Brannstrom J., Flamholc L., Scherrer A., Weber R., Cavassini M., Calmy A., Furrer H., Battegay M., Schmid P., Kuznetsova A., Mikhalik J., Sluzhynska M., Milinkovic A., Johnson A. M., Simons E., Edwards S., Phillips A., Johnson M. A., Mocroft A., Orkin C., Winston A., Clarke A., Leen C., Karpov I., Losso M., Lundgren J., Rockstroh J., Aho I., Rasmussen L. D., Svedhem V., Wandeler G., Pradier C., Chkhartishvili N., Matulionyte R., Oprea C., Kowalska J. D., Begovac J. +199 moreopenaire +7 more sourcesAttacking the public health crisis of hepatocellular carcinoma at its roots
Hepatology, EarlyView., 2022 Abstract
As the third most common cause of cancer‐related death worldwide with significant mortality rates in the United States, hepatocellular carcinoma has strong association with cirrhosis and chronic hepatitis B virus (HBV) with a growing at‐risk population from the rise in chronic liver disease from alcohol use and nonalcoholic fatty liver disease.Hannah M. Lee, Steven D. Lidofsky, Tamar H. Taddei, Lisa J. Townshend‐Bulson +3 morewiley +1 more sourceHCV avidity as a tool for detection of recent HCV infection: Sensitivity depends on HCV genotype [PDF]
Journal of Medical Virology, 2017 Accurate detection of incident hepatitis C virus (HCV) infection is required to target and evaluate public health interventions, but acute infection is largely asymptomatic and difficult to detect using traditional methods. Our aim was to evaluate a previously developed HCV avidity assay to distinguish acute from chronic HCV infection.Samantha J. Shepherd, Scott A. McDonald, Norah E. Palmateer, Rory N. Gunson, Celia Aitken, Gregory J. Dore, David J. Goldberg, Tanya L. Applegate, Andrew R. Lloyd, Behzad Hajarizadeh, Jason Grebely, Sharon J. Hutchinson +11 moreopenaire +3 more sourcesHealth disparities in chronic liver disease
Hepatology, EarlyView., 2022 Abstract
The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.Ani Kardashian, Marina Serper, Norah Terrault, Lauren D. Nephew +3 morewiley +1 more sourceExcluding hepatitis C virus (HCV) infection by serology in young infants of HCV infected mothers
, 2005 Aim: To identify the age at which HCV infection can be accurately excluded by serology in young children born to HCV-infected mothers and to determine an appropriate schedule of antibody testing, most informative to clinical practice.FALDELLA, GIACOMO, England, K, . . . ], LANARI, MARCELLO, Pembrey, L, European Paediatric HCV Network [. . ., Tovo, PA, Newell, ML +7 morecore +1 more sourceGenetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development [PDF]
, 2013 Background: Vitamin D insufficiency has been associated with the occurrence of various types of cancer, but causal relationships remain elusive. We therefore aimed to determine the relationship between genetic determinants of vitamin D serum levels and ...Jörg Bojunga, Stéphanie Bibert (3279381), Lange, Christian M., Mullhaupt, B., Ochi Hidenori, Thomas Berg (186372), Müller Tobias, Ochi, H., David Semela (416437), Gouttenoire, J., Müllhaupt, Beat, Kenichi Morikawa (416434), Nischalke, Hans-Dieter, Ulrich Spengler (205545), Ochi, Hidenori, Lange, Christian M, Dufour, J. F., David Semela, Malinverni Raffaele, Meri Gorgievski-Hrisoho (416435), Bochud Pierre-Yves, Francesco Negro (205592), Semela, David, Beat Müllhaupt (416436), Nischalke, H. D., Chayama, Kazuaki, Bochud, P. Y., Gouttenoire Jérôme, Negro, F., Cerny, A., Zoltan Kutalik, Kazuaki Chayama (128675), Lange, Christian, Negro Francesco, Pierre-Yves Bochud, Morikawa, Kenichi, Bibert, S., Malinverni, R., Spengler, U., Bibert, Stéphanie, Moradpour, Darius, Darius Moradpour (15815), Bochud, P.Y., Dufour, J.F., Hans-Dieter Nischalke (416433), Heim Markus H., Raffaele Malinverni (316140), Jean-François Dufour, Meri Gorgievski-Hrisoho, Berg Thomas, Miki, D., Vinciguerra, Manlio, Hidenori Ochi (128649), Gorgievski-Hrisoho, M., Andreas Cerny, Dufour, Jean-François, Kazuaki Chayama, Ulrich Spengler, Heim, M. H., Muller, T., Hans-Dieter Nischalke, Francesco Negro, Gorgievski-Hrisoho, Meri, Berg, Thomas, Markus H Heim, Darius Moradpour, Chayama, K., Kenichi Morikawa, Miki Daiki, Dufour Jean-François, Pierre-Yves Bochud (205597), Daiki Miki (128628), Miki, Daiki, Raffaele Malinverni, Bojunga Jörg, Jérôme Gouttenoire, Spengler Ulrich, Berg, T., Nischalke, H.D., Hidenori Ochi, Spengler, Ulrich, Cerny Andreas, Kutalik, Z., Zoltan Kutalik (3965672), Andreas Cerny (189787), Christian M Lange, Gouttenoire, Jérôme, Dufour, Jean-François Jacques, Gorgievski, Meri, Thomas Berg, Malinverni, Raffaele, Moradpour Darius, Beat Müllhaupt, Semela David, Daiki Miki, Chayama Kazuaki, Bojunga, Jörg, Stéphanie Bibert, Gorgievski-Hrisoho Meri, Tobias Müller (163591), Swiss Hepatitis C Cohort Study Group, Christian M. Lange (316130), Bojunga, J., Kutalik Zoltan, Tobias Müller, Lange, C. M., Lange Christian M., Cerny, Andreas, Markus H. Heim (237987), Lange, C.M., Kutalik, Zoltán, Heim, M.H., Nischalke Hans-Dieter, Moradpour, D., Morikawa, K., Semela, D., Jörg Bojunga (316147), Morikawa Kenichi, Negro, Francesco, Müller, Tobias, Hiroshima Liver Study Group, Bochud, Pierre-Yves, Bibert Stéphanie, Heim, Markus H., Müllhaupt Beat, Heim, Markus H, Jérôme Gouttenoire (235184), Jean-François Dufour (5654965) +127 morecore +3 more sources